PF-06860932

Product Name: PF-06860932
CAS No.: 2226970-01-8
Chemical Name: PF-06860932
Synonyms: PF-06860932;CFTR corrector 6;7H-Pyrrolo[2,3-d]pyrimidine-6-carbonitrile, 4-amino-7-[[1-(2-fluorophenyl)-1H-pyrazol-4-yl]methyl]-5-[2-(trifluoromethyl)-5-pyrimidinyl]-
CBNumber: CB54667293
Molecular Formula: C22H13F4N9
Formula Weight: 479.39
MOL File: 2226970-01-8.mol

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PF-06860932 Property

Boiling point:: 697.4±55.0 °C(Predicted)
Density: 1.60±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
pka: 3.23±0.30(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0135420
Product name: CFTRcorrector6
Packaging: 5mg
Price: $480
Updated: 2021/12/16

ChemScene

Product number: CS-0135420
Product name: CFTRcorrector6
Packaging: 10mg
Price: $800
Updated: 2021/12/16

ChemScene

Product number: CS-0135420
Product name: CFTRcorrector6
Packaging: 25mg
Price: $1550
Updated: 2021/12/16

ChemScene

Product number: CS-0135420
Product name: CFTRcorrector6
Packaging: 50mg
Price: $2400
Updated: 2021/12/16

ChemScene

Product number: CS-0135420
Product name: CFTRcorrector6
Packaging: 100mg
Price: $3600
Updated: 2021/12/16

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PF-06860932 Chemical Properties,Usage,Production

Biological Activity

CFTR corrector 6 is a potent potentiator of Cystic Fibrosis Transmembrane conductance Regulator (CFTR). CFTR corrector 6 has the potential for cystic fibrosis (CF) and other CFTR associated disorders research[1]. CFTR corrector 6 (Example 27) has EC50s of 1.25 nM and 1.27 nM for primary cystic fibrosis human bronchial epithelial (CF hBE) cells and fischer rat thyroid (FRT) cell lines[1].

References

[1]. Joseph Walter Strohbach, et al. Pyrrolopyrimidines as cftr potentiators. WO2018094137A1

PF-06860932 Preparation Products And Raw materials

Raw materials

Preparation Products

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PF-06860932 Suppliers

China 7 United States 2 Global 9

TargetMol Chemicals Inc.

Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Country: United States
ProdList: 19863
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 52925
Advantage: 58

2226970-01-8, PF-06860932Related Search:

PF-06860932

CFTR corrector 6

7H-Pyrrolo[2,3-d]pyrimidine-6-carbonitrile, 4-amino-7-[[1-(2-fluorophenyl)-1H-pyrazol-4-yl]methyl]-5-[2-(trifluoromethyl)-5-pyrimidinyl]-

2226970-01-8