ChemicalBook > CAS DataBase List > GAK inhibitor 49

GAK inhibitor 49

Product Name
GAK inhibitor 49
CAS No.
319492-82-5
Chemical Name
GAK inhibitor 49
Synonyms
AK inhibitor 49;GAK inhibitor 49;GAK inhibitor 49, 10 mM in DMSO;6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine;4-Quinolinamine, 6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)-;NAK,selective,GAK inhibitor-49,GAK inhibitor49,GAK inhibitor 49,Inhibitor,inhibit,ATP-competitive,family
CBNumber
CB54667925
Molecular Formula
C20H22N2O5
Formula Weight
370.4
MOL File
319492-82-5.mol
More
Less

GAK inhibitor 49 Property

Boiling point:
494.8±45.0 °C(Predicted)
Density 
1.223±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 50 mg/mL (134.99 mM; ultrasonic and warming and heat to 80°C)
form 
Solid
pka
7+-.0.50(Predicted)
color 
White to off-white
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Ambeed
Product number
A1359459
Product name
6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
Purity
98%
Packaging
1mg
Price
$39
Updated
2021/12/16
Ambeed
Product number
A1359459
Product name
6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
Purity
98%
Packaging
5mg
Price
$55
Updated
2021/12/16
Ambeed
Product number
A1359459
Product name
6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
Purity
98%
Packaging
10mg
Price
$100
Updated
2021/12/16
Ambeed
Product number
A1359459
Product name
6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
Purity
98%
Packaging
25mg
Price
$170
Updated
2021/12/16
Ambeed
Product number
A1359459
Product name
6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
Purity
98%
Packaging
50mg
Price
$290
Updated
2021/12/16
More
Less

GAK inhibitor 49 Chemical Properties,Usage,Production

Uses

GAK inhibitor 49 is a potent, ATP-competitive and highly selective cyclin G associated kinase (GAK) inhibitor with a Ki of 0.54 nM and a cell IC50 of 56 nM. GAK inhibitor 49 also shows binding to RIPK2[1].

References

[1] Asquith CRM, et al. Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase. ChemMedChem. 2018;13(1):48-66. DOI:10.1002/cmdc.201700663

GAK inhibitor 49 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

GAK inhibitor 49 Suppliers

Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4817
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
86249
Advantage
60
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
9675
Advantage
55
Shanghai SuperLan Chemcial Technique Centre
Tel
0-2022843681 15618226720
Fax
+86-21-51601218
Email
chaolaichem@foxmail.com
Country
China
ProdList
9955
Advantage
58
Zhengzhou Convergence Chemical Co. LTD
Tel
0371-0371-53736046 13393710386
Fax
QQ:2853979814
Email
3941078109@qq.com
Country
China
ProdList
9779
Advantage
58
Jinan Jiuli Biotechnology Co. , Ltd.
Tel
15865264761
Email
486064515@qq.com
Country
China
ProdList
4885
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
Hefei Mokai Pharmaceutical Technology Co., Ltd
Tel
18130062233
Email
690231469@qq.com
Country
China
ProdList
8100
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
59936
Advantage
58

319492-82-5, GAK inhibitor 49Related Search:


  • GAK inhibitor 49
  • 4-Quinolinamine, 6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)-
  • 6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
  • NAK,selective,GAK inhibitor-49,GAK inhibitor49,GAK inhibitor 49,Inhibitor,inhibit,ATP-competitive,family
  • AK inhibitor 49
  • GAK inhibitor 49, 10 mM in DMSO
  • 319492-82-5