NCT-505

Product Name: NCT-505
CAS No.: 2231079-74-4
Chemical Name: NCT-505
Synonyms: NCT-505 free base;NCT-505, 10 mM in DMSO;inhibit,Aldehyde Dehydrogenase (ALDH),NCT-505,Inhibitor,NCT505,NCT 505;1-(6-Fluoro-3-(4-(methylsulfonyl)piperazine-1-carbonyl)quinolin-4-yl)-4-phenylpiperidine-4-carbonitrile;4-Piperidinecarbonitrile, 1-[6-fluoro-3-[[4-(methylsulfonyl)-1-piperazinyl]carbonyl]-4-quinolinyl]-4-phenyl-;1-(6-Fluoro-3-(4-(methylsulfonyl)piperazine-1-carbonyl)quinolin-4-yl)-4-phenylpiperidine-4-carbonitrile , NCT-505
CBNumber: CB54672251
Molecular Formula: C27H28FN5O3S
Formula Weight: 521.61
MOL File: 2231079-74-4.mol

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NCT-505 Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

A1 Biochem Labs

Product number: 6586436
Product name: 1-(6-Fluoro-3-(4-(methylsulfonyl)piperazine-1-carbonyl)quinolin-4-yl)-4-phenylpiperidine-4-carbonitrile
Purity: 95%
Packaging: 1g
Price: $1500
Updated: 2021/12/16

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NCT-505 Chemical Properties,Usage,Production

Description

NCT-505 is an Orally Bioavailable aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitor with Potent Cellular Activity (IC50 = 7 nM). NCT-505 demonstrated target engagement in a cellular thermal shift assay (CETSA), inhibited the formation of 3D spheroid cultures of OV-90 cancer cells, and potentiated the cytotoxicity of paclitaxel in SKOV-3-TR, a paclitaxel resistant ovarian cancer cell line. NCT-505 also exhibit high specificity over other ALDH isozymes and unrelated dehydrogenases.

NCT-505 Preparation Products And Raw materials

Raw materials

Preparation Products

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NCT-505 Suppliers

China 9 United States 3 Global 12

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 52924
Advantage: 58

2231079-74-4, NCT-505Related Search:

NCT-505 free base

4-Piperidinecarbonitrile, 1-[6-fluoro-3-[[4-(methylsulfonyl)-1-piperazinyl]carbonyl]-4-quinolinyl]-4-phenyl-

1-(6-Fluoro-3-(4-(methylsulfonyl)piperazine-1-carbonyl)quinolin-4-yl)-4-phenylpiperidine-4-carbonitrile

inhibit,Aldehyde Dehydrogenase (ALDH),NCT-505,Inhibitor,NCT505,NCT 505

1-(6-Fluoro-3-(4-(methylsulfonyl)piperazine-1-carbonyl)quinolin-4-yl)-4-phenylpiperidine-4-carbonitrile , NCT-505

NCT-505, 10 mM in DMSO

2231079-74-4

C27H28FN5O3S