ChemicalBook > CAS DataBase List > GLX351322

GLX351322

Product Name
GLX351322
CAS No.
835598-94-2
Chemical Name
GLX351322
Synonyms
CS-2871;GLX 351322;GLX-351322;GLX351322,GLX-351322,GLX 351322,NADPH Oxidase,NOX,Inhibitor,inhibit;Ethyl 2-(2-(4-(furan-2-carbonyl)piperazin-1-yl)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate;Ethyl 2-(2-(4-(furan-2-carbonyl)piperazin-1-yl)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate , GLX351322;4H-Cyclopenta[b]thiophene-3-carboxylic acid, 2-[[2-[4-(2-furanylcarbonyl)-1-piperazinyl]acetyl]amino]-5,6-dihydro-, ethyl ester
CBNumber
CB54672882
Molecular Formula
C21H25N3O5S
Formula Weight
431.51
MOL File
835598-94-2.mol
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GLX351322 Property

solubility 
DMSO:20.0(Max Conc. mg/mL);46.35(Max Conc. mM)
DMF:1.0(Max Conc. mg/mL);2.32(Max Conc. mM)
DMF:PBS (pH 7.2) (1:2):0.33(Max Conc. mg/mL);0.76(Max Conc. mM)
Ethanol:4.0(Max Conc. mg/mL);9.27(Max Conc. mM)
form 
A crystalline solid
color 
White to off-white
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Safety

HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2546
Product name
GLX351322
Purity
≥98% (HPLC)
Packaging
5MG
Price
$95.3
Updated
2023/06/20
Sigma-Aldrich
Product number
SML2546
Product name
GLX351322
Purity
≥98% (HPLC)
Packaging
25MG
Price
$385
Updated
2023/06/20
ChemScene
Product number
CS-0018088
Product name
GLX351322
Purity
99.48%
Packaging
25mg
Price
$500
Updated
2021/12/16
ChemScene
Product number
CS-0018088
Product name
GLX351322
Purity
99.48%
Packaging
5mg
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-0018088
Product name
GLX351322
Purity
99.48%
Packaging
50mg
Price
$850
Updated
2021/12/16
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GLX351322 Chemical Properties,Usage,Production

Biological Activity

GLX351322 is an inhibitor of NADPH oxidase 4 (NOX4). It can inhibits tetracycline-induced hydrogen peroxide production in NOX4-overexpressing cells with IC50 of 5 μM.

in vitro

GLX351322 is an inhibitor of NADPH oxidase 4, and inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC 50 of 5 μM. GLX351322 shows weak activity against NOX2 in hPBMC cells ( IC 50 , 40 μM).

in vivo

GLX351322 (3.8 mg/kg/day, po) ameliorates HFD-induced hyperglycemia in mice.

target

TargetValue
NOX4
(Cell-free assay)		 5 μM

GLX351322 Preparation Products And Raw materials

Raw materials

Preparation Products

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GLX351322 Suppliers

China 36 India 1 United States 7 Global 44
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
Cckinase, Inc.
Tel
+1 (732)236-3202
Email
sales@cckinase.com
Country
United States
ProdList
2738
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58

835598-94-2, GLX351322Related Search:


  • CS-2871
  • GLX 351322;GLX-351322
  • 4H-Cyclopenta[b]thiophene-3-carboxylic acid, 2-[[2-[4-(2-furanylcarbonyl)-1-piperazinyl]acetyl]amino]-5,6-dihydro-, ethyl ester
  • GLX351322,GLX-351322,GLX 351322,NADPH Oxidase,NOX,Inhibitor,inhibit
  • Ethyl 2-(2-(4-(furan-2-carbonyl)piperazin-1-yl)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate
  • Ethyl 2-(2-(4-(furan-2-carbonyl)piperazin-1-yl)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate , GLX351322
  • 835598-94-2