ChemicalBook > CAS DataBase List > 2-BROMO-4-METHYL-1H-IMIDAZOLE

2-BROMO-4-METHYL-1H-IMIDAZOLE

Product Name
2-BROMO-4-METHYL-1H-IMIDAZOLE
CAS No.
23328-88-3
Chemical Name
2-BROMO-4-METHYL-1H-IMIDAZOLE
Synonyms
2-Bromo-4-methylimidazole;2-bromo-5-methyl-1h-imidazole;2-BROMO-4-METHYL-1H-IMIDAZOLE;4-methyl-2-bromo-1H-imidazole;1H-Imidazole, 2-bromo-5-methyl-
CBNumber
CB5469512
Molecular Formula
C4H5BrN2
Formula Weight
161
MOL File
23328-88-3.mol
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2-BROMO-4-METHYL-1H-IMIDAZOLE Property

Melting point:
110-114
Boiling point:
280.7±33.0 °C(Predicted)
Density 
1.723±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
powder
pka
11.66±0.10(Predicted)
color 
Yellow
InChI
InChI=1S/C4H5BrN2/c1-3-2-6-4(5)7-3/h2H,1H3,(H,6,7)
InChIKey
AYQISCMXBQVMSY-UHFFFAOYSA-N
SMILES
C1(Br)NC(C)=CN=1
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Safety

Hazard Codes 
Xi
Hazard Note 
Irritant
HS Code 
2933299090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC
Product number
B697173
Product name
2-Bromo-4-methyl-1H-imidazole
Packaging
250mg
Price
$65
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB158303
Product name
2-Bromo-4-methyl-1H-imidazole
Packaging
250mg
Price
$75
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB158303
Product name
2-Bromo-4-methyl-1H-imidazole
Packaging
500mg
Price
$120
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB158303
Product name
2-Bromo-4-methyl-1H-imidazole
Packaging
1g
Price
$180
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB158303
Product name
2-Bromo-4-methyl-1H-imidazole
Packaging
2g
Price
$300
Updated
2021/12/16
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2-BROMO-4-METHYL-1H-IMIDAZOLE Chemical Properties,Usage,Production

Synthesis

219814-29-6

23328-88-3

General procedure for the synthesis of 2-bromo-4-methyl-1H-imidazole from 2,5-dibromo-4-methylimidazole: [Example 6]; At room temperature, 23.9 g (100.0 mmol) of 2,5-dibromo-4-methylimidazole, 29.4 g (300.0 mmol) of cyclohexanone, and 23.9 g (259.4 mmol) of toluene were mixed, and during stirring, slow addition of 22.5 g (150.0 mmol) of sodium iodide to prepare the reaction solution. The reaction solution was stirred at 105 °C for 12 h under nitrogen protection, followed by cooling in an ice bath and continued stirring for 1 h. The reaction solution was analyzed by HPLC. Analysis of the reaction solution by HPLC confirmed the formation of 13.7 g (82.3 mmol, conversion: 85.3%) of 2-bromo-4-methyl-1H-imidazole. The reaction solution was concentrated under reduced pressure and purified by silica gel column chromatography (eluent: ethyl acetate/hexane mixed system). The product-containing fractions were collected, and after evaporation to remove volatile components, 2-bromo-4-methyl-1H-imidazole crystals were obtained in a yield of 12.6 g (yield: 78.1%). The obtained crystals were further confirmed to be 2-bromo-4-methyl-1H-imidazole by comparing the NMR spectrum of the product with that of the standard sample.

References

[1] Patent: EP2141151, 2010, A1. Location in patent: Page/Page column 7

2-BROMO-4-METHYL-1H-IMIDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-BROMO-4-METHYL-1H-IMIDAZOLE Suppliers

China 77 India 1 United Kingdom 2 United States 10 Global 90
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
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View Lastest Price from 2-BROMO-4-METHYL-1H-IMIDAZOLE manufacturers

Career Henan Chemical Co
Product
2-Bromo-5-methyl-1H-imidazole 23328-88-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2020-01-09

23328-88-3, 2-BROMO-4-METHYL-1H-IMIDAZOLERelated Search:

8-Bromotheophylline 2-BROMO-1H-IMIDAZOLE-4,5-DICARBONITRILE 2-BROMO-1-METHYL-1H-IMIDAZOLE-4,5-DICARBONITRILE 8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE CHEMBRDG-BB 4023079 8-BROMOGUANINE 8-BROMOGUANOSINE 5'-MONOPHOSPHATE SODIUM SALT 8-BROMO-7-ETHYL-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE 8-BR-CGMP 2',3',5-TRI-O-ACETYL-8-BROMOGUANOSINE AKOS BC-1749 8-BROMO-1,3,7-TRIMETHYL-3,7-DIHYDRO-PURINE-2,6-DIONE 8-BROMOXANTHOSINE 8-BROMO-1,3-DIMETHYL-7-(2-OXO-2-PHENYLETHYL)-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE 2-AMINO-8-BROMO-9-((2R,3R,4S,5R)-3,4-DIHYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-2-YL)-1,9-DIHYDRO-PURIN-6-ONE 7-BENZYL-8-BROMO-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE 2-AMINO-8-BROMO-9-[3,4-DIHYDROXY-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL]-6,9-DIHYDRO-1H-PURIN-6-ONE 8-BROMO-3-METHYL-7-(2-OXO-2-PHENYL-ETHYL)-3,7-DIHYDRO-PURINE-2,6-DIONE

  • 2-Bromo-4-methylimidazole
  • 2-BROMO-4-METHYL-1H-IMIDAZOLE
  • 2-bromo-5-methyl-1h-imidazole
  • 1H-Imidazole, 2-bromo-5-methyl-
  • 4-methyl-2-bromo-1H-imidazole
  • 23328-88-3
  • blocks
  • Bromides
  • Imidazoles