ChemicalBook > CAS DataBase List > 8-Bromotheophylline

8-Bromotheophylline

Product Name
8-Bromotheophylline
CAS No.
10381-75-6
Chemical Name
8-Bromotheophylline
Synonyms
Nsc164940;AKOS NCG-0005;bromotheophylline;8-Bromotheophyline;8-BROMOTHEOPHYLLINE;LABOTEST-BB LT00134545;Theophylline, 8-bromo-;8-BROMOTHEOPHYLLINE 97%;8-Bromotheophylline >8-Bromotheophylline ,97%
CBNumber
CB0105862
Molecular Formula
C7H7BrN4O2
Formula Weight
259.06
MOL File
10381-75-6.mol
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8-Bromotheophylline Property

Melting point:
295-297°C
Boiling point:
469.5±55.0 °C(Predicted)
Density 
1.862±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
pka
pKa 5.45±0.1(H2O t=24) (Uncertain)
form 
Solid
color 
White to Off-White
BRN 
203069
CAS DataBase Reference
10381-75-6
EPA Substance Registry System
1H-Purine-2,6-dione, 8-bromo-3,7-dihydro-1,3-dimethyl- (10381-75-6)
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Safety

Risk Statements 
20/21/22
Safety Statements 
24/25-36/37
RIDADR 
2811
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29395900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S168378
Product name
8-BROMO-1,3-DIMETHYL-3,7-DIHYDRO-PURINE-2,6-DIONE
Purity
Aldrich
Packaging
50mg
Price
$110
Updated
2024/03/01
Sigma-Aldrich
Product number
1077708
Product name
8-BROMO-1,3-DIMETHYL-3,7-DIHYDRO-PURINE-2,6-DIONE
Packaging
400mg
Price
$1310
Updated
2024/03/01
TCI Chemical
Product number
B3456
Product name
8-Bromotheophylline
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$148
Updated
2024/03/01
TCI Chemical
Product number
B3456
Product name
8-Bromotheophylline
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$509
Updated
2024/03/01
TRC
Product number
B688150
Product name
8-Bromotheophylline
Packaging
10g
Price
$690
Updated
2021/12/16
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8-Bromotheophylline Chemical Properties,Usage,Production

Description

Bromotheophylline is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline. From this mixture, bromotheophylline acts as a weak diuretic that has been used along with some analgesics to relieve the symptoms of premenstrual syndrome. Bromotheophylline is categorized on the FDA as a drug substance with an inactive state since March, 1980. It is also approved by Health Canada to be used alone or in combination with [DB00316] in OTC products.

Chemical Properties

White Crystalline Powder

Uses

The active component in the diuretic Diurex.

Purification Methods

It is purified by dissolving in the minimum volume of dilute NaOH (charcoal), filtering and acidifying to pH ca 3.5-4. The solid that separates is collected, dried in vacuo at 100o and stored in a dark container. It has also been recrystallised from EtOH or AcOH. [Blitz & Beck J Prakt Chem [2] 118 158 1928, Fischer & Ach Chem Ber 28 3142 1895, Beilstein 26 H 476, 26 II 227, 26 III/IV 2447.]

8-Bromotheophylline Preparation Products And Raw materials

Raw materials

Preparation Products

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8-Bromotheophylline Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
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View Lastest Price from 8-Bromotheophylline manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
8-Bromotheophylline 10381-75-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
8-BROMOTHEOPHYLLINE 10381-75-6
Price
US $1.00/KG
Min. Order
1KG
Purity
98%HPLC
Supply Ability
10tons
Release date
2020-01-20

10381-75-6, 8-BromotheophyllineRelated Search:


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  • 8-Bromotheophylline (1077708)
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  • Pharmaceutical Raw Materials
  • Nucleotides and Nucleosides
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  • Nucleotides