ChemicalBook > CAS DataBase List > 8-Bromotheophylline

8-Bromotheophylline

Product Name
8-Bromotheophylline
CAS No.
10381-75-6
Chemical Name
8-Bromotheophylline
Synonyms
Nsc164940;AKOS NCG-0005;bromotheophylline;8-Bromotheophyline;8-BROMOTHEOPHYLLINE;LABOTEST-BB LT00134545;Theophylline, 8-bromo-;8-BROMOTHEOPHYLLINE 97%;8-Bromotheophylline >8-Bromotheophylline ,97%
CBNumber
CB0105862
Molecular Formula
C7H7BrN4O2
Formula Weight
259.06
MOL File
10381-75-6.mol
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8-Bromotheophylline Property

Melting point:
295-297°C
Boiling point:
469.5±55.0 °C(Predicted)
Density 
1.862±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
pka
pKa 5.45±0.1(H2O t=24) (Uncertain)
form 
Solid
color 
White to Off-White
BRN 
203069
CAS DataBase Reference
10381-75-6
EPA Substance Registry System
1H-Purine-2,6-dione, 8-bromo-3,7-dihydro-1,3-dimethyl- (10381-75-6)
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Safety

Risk Statements 
20/21/22
Safety Statements 
24/25-36/37
RIDADR 
2811
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29395900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S168378
Product name
8-BROMO-1,3-DIMETHYL-3,7-DIHYDRO-PURINE-2,6-DIONE
Purity
Aldrich
Packaging
50mg
Price
$110
Updated
2024/03/01
Sigma-Aldrich
Product number
1077708
Product name
8-BROMO-1,3-DIMETHYL-3,7-DIHYDRO-PURINE-2,6-DIONE
Packaging
400mg
Price
$1310
Updated
2024/03/01
TCI Chemical
Product number
B3456
Product name
8-Bromotheophylline
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$148
Updated
2024/03/01
TCI Chemical
Product number
B3456
Product name
8-Bromotheophylline
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$509
Updated
2024/03/01
TRC
Product number
B688150
Product name
8-Bromotheophylline
Packaging
10g
Price
$690
Updated
2021/12/16
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8-Bromotheophylline Chemical Properties,Usage,Production

Description

Bromotheophylline is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline. From this mixture, bromotheophylline acts as a weak diuretic that has been used along with some analgesics to relieve the symptoms of premenstrual syndrome. Bromotheophylline is categorized on the FDA as a drug substance with an inactive state since March, 1980. It is also approved by Health Canada to be used alone or in combination with [DB00316] in OTC products.

Chemical Properties

White Crystalline Powder

Uses

The active component in the diuretic Diurex.

Purification Methods

It is purified by dissolving in the minimum volume of dilute NaOH (charcoal), filtering and acidifying to pH ca 3.5-4. The solid that separates is collected, dried in vacuo at 100o and stored in a dark container. It has also been recrystallised from EtOH or AcOH. [Blitz & Beck J Prakt Chem [2] 118 158 1928, Fischer & Ach Chem Ber 28 3142 1895, Beilstein 26 H 476, 26 II 227, 26 III/IV 2447.]

8-Bromotheophylline Preparation Products And Raw materials

Raw materials

Acetic anhydride Theophylline Hydrogen bromide Nitric acid

Preparation Products

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8-Bromotheophylline Suppliers

Americas 1 Canada 1 China 81 Europe 1 Germany 3 India 15 Japan 1 Russia 1 South Africa 1 Turkey 1 United Kingdom 8 United States 13 Global 127
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28398
Advantage
80
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View Lastest Price from 8-Bromotheophylline manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
8-Bromotheophylline 10381-75-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
8-BROMOTHEOPHYLLINE 10381-75-6
Price
US $1.00/KG
Min. Order
1KG
Purity
98%HPLC
Supply Ability
10tons
Release date
2020-01-20

10381-75-6, 8-BromotheophyllineRelated Search:

8-Bromotheophylline 8-BROMOXANTHINE 8-BROMO-7-ETHYL-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE 8-BROMO-7-(3-CHLOROPROPYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE 8-BROMO-7-(2-BROMOPROPYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE ETHYL 2-(8-BROMO-1,3-DIMETHYL-2,6-DIOXO-2,3,6,7-TETRAHYDRO-1H-PURIN-7-YL)ACETATE 8-BROMO-1,3-DIMETHYL-7-(2-OXO-2-PHENYLETHYL)-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE 8-BROMO-7-(3-CHLORO-2-HYDROXYPROPYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE 8-BROMO-7-(2-HYDROXYPROPYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE AKOS BC-1749 ETHYL 4-(8-BROMO-1,3-DIMETHYL-2,6-DIOXO-2,3,6,7-TETRAHYDRO-1H-PURIN-7-YL)BUTANOATE 8-BROMO-1,3,7-TRIMETHYL-3,7-DIHYDRO-PURINE-2,6-DIONE 8-BROMO-1,3-DIMETHYL-7-(2-OXOPROPYL)-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE 8-BROMO-7-(2-BROMOBUTYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE 8-BROMO-1,3-DIMETHYL-7-PHENETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE 8-BROMO-7-(2-CHLOROBUTYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE 8-BROMO-7-(2-CHLOROPROPYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE 8-BROMO-7-(2-HYDROXYBUTYL)-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE

  • 8-bromo-3,7-dihydro-1,3-dimethyl-1h-purine-6-dione
  • AKOS NCG-0005
  • 8-BROMOTHEOPHYLLINE
  • 8-BROMO-3,7-DIHYDRO-1,3-DIMETHYL-1H-PURINE-2,6-DIONE
  • 8-BROMO-1,3-DIMETHYL-3,7-DIHYDRO-PURINE-2,6-DIONE
  • LABOTEST-BB LT00134545
  • 8-BROMOTHEOPHYLLINE 97%
  • 1,3-Dimethyl-8-bromoxanthine
  • bromotheophylline
  • 8-Bromotheophylline ,97%
  • 8-bromo-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
  • 8-Bromotheophylline, ≥98%
  • 1H-Purine-2,6-dione, 8-bromo-3,7-dihydro-1,3-dimethyl-
  • 8-Bromotheophyline
  • Nsc164940
  • Theophylline, 8-bromo-
  • 8-bromo-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione(SALTDATA: FREE)
  • 8-Bromotheophylline (400 mg)
  • 8-BroMo-1,3-diMethyl-1H-purine-2,6(3H,9H)-dione
  • 8-broMo-1,3-diMethyl-1H-purine-2,6(3H,7H)-dione
  • 8-Bromo-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
  • 8-Bromotheophylline &gt
  • 1H-Purine-2,6-dione, 8-bromo-3,9-dihydro-1,3-dimethyl-
  • 8-Bromotheophylline (1077708)
  • 10381-75-6
  • C7H7BrN4O2
  • Pharmaceutical Raw Materials
  • Nucleotides and Nucleosides
  • Bases & Related Reagents
  • Nucleotides