ChemicalBook > CAS DataBase List > PKB ALPHA
PKB ALPHA
- Product Name
- PKB ALPHA
- Chemical Name
- PKB ALPHA
- Synonyms
- AKT1;PKB ALPHA;AKT1 ACTIVE HUMAN;PROTEIN KINASE B-ALPHA;Human AKT1 Protein, His Tag;PKB α, Protein KinaseB-α
- CBNumber
- CB5471807
- Formula Weight
- 0
- MOL File
- Mol file
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PKB ALPHA Property
- storage temp.
- −70°C
- form
- aqueous glycerol solution
- biological source
- human
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Safety
- WGK Germany
- 1
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SRP0353
- Product name
- Akt1 active human
- Purity
- recombinant, expressed in baculovirus infected <I>Sf</I>9 cells, ≥75% (SDS-PAGE)
- Packaging
- 10 μg
- Price
- $563
- Updated
- 2025/07/31
Usbiological
- Product number
- A1125A
- Product name
- Akt1
- Packaging
- 50ul
- Price
- $488
- Updated
- 2021/12/16
Usbiological
- Product number
- A1125-05C
- Product name
- Akt1
- Packaging
- 50ug
- Price
- $631
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb528473
- Product name
- AKT1
- Packaging
- 10μg
- Price
- $290.7
- Updated
- 2021/12/16
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PKB ALPHA Chemical Properties,Usage,Production
Uses
Akt1 active human has been used for the testing of recombinant mouse p21 proteins as its substrates using in vitro protein kinase assay.
Biological Activity
AKT1 (v-akt murine thymoma viral oncogene homolog 1) is responsible for the phosphorylation and cytoplasmic localization of CKDN1A (cyclin-dependent kinase (CDK) inhibitor 1, also referred to as p21). However, p21 is one of the CDKNs which normally resides in the nucleus and its cytoplasmic localization, mediated by AKT1, is common to various cancers where it suppresses proteins essential for apoptosis. Studies show th at up-regulation of AKT1 serves as a poor prognostic marker in breast cancer, which however, depends upon factors including population, hormone receptor status, and hormonal or trastuzumab therapy status.
PKB ALPHA Preparation Products And Raw materials
Raw materials
Preparation Products
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