ChemicalBook > CAS DataBase List > CP-424,174
CP-424,174
- Product Name
- CP-424,174
- CAS No.
- 210825-31-3
- Chemical Name
- CP-424,174
- Synonyms
- CP-424,174;CP-424,174 >=98% (HPLC);N-((4-Chloro-2,6-diisopropylphenyl)carbamoyl)-3-(2-hydroxypropan-2-yl)benzenesulfonamide;CP424174,IL-1β,NLRP3,Inhibitor,CP 424174,CP-424174,Inflammasome,inhibit,NOD-like Receptor (NLR);N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide;Benzenesulfonamide, N-[[[4-chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)-
- CBNumber
- CB54741315
- Molecular Formula
- C22H29ClN2O4S
- Formula Weight
- 452.99
- MOL File
- 210825-31-3.mol
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CP-424,174 Property
- Density
- 1?+-.0.06 g/cm3(Predicted)
- storage temp.
- room temp
- solubility
- DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:5): 0.16 mg/ml
- form
- powder
- pka
- 4.67±0.10(Predicted)
- color
- white to beige
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- PZ0347
- Product name
- CP-424,174
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $114
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- PZ0347
- Product name
- CP-424,174
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $464
- Updated
- 2024/03/01
Tocris
- Product number
- 6107
- Product name
- CP424174
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $117
- Updated
- 2021/12/16
Tocris
- Product number
- 6107
- Product name
- CP424174
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $393
- Updated
- 2021/12/16
TRC
- Product number
- C781493
- Product name
- CP424174
- Packaging
- 1mg
- Price
- $75
- Updated
- 2021/12/16
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CP-424,174 Chemical Properties,Usage,Production
Biochem/physiol Actions
CP-424,174 is a cytokine release inhibitory drugs (CRID) that inhibits the post-translational processing and secretion of IL-1b in response to LPS and ATP in human monocytes. It is quite possible that similarly to CP-456,773 (termed CRID3), CP-424,174 inhibits both NLRP3 and AIM2 inflammasomes by preventing ASC oligomerisation.
CP-424,174 Preparation Products And Raw materials
Raw materials
Preparation Products
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