1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid

Product Name: 1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid
CAS No.: 1869118-25-1
Chemical Name: 1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid
Synonyms: Upatinib impurity 41;Upadacitinib Impurity 41;Impurities in Upatinib 17;1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid;1H-Pyrrole-1,3-dicarboxylic acid, 4-ethyl-2,5-dihydro-, 1-(phenylmethyl) ester;8-((3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidin-3-yl)-6- ethyl-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-6-ium iodide
CBNumber: CB54747852
Molecular Formula: C15H17NO4
Formula Weight: 275.3
MOL File: 1869118-25-1.mol

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1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid Property

Boiling point:: 452.3±45.0 °C(Predicted)
Density: 1.267±0.06 g/cm3(Predicted)
pka: 4.28±0.20(Predicted)
InChI: InChI=1S/C15H17NO4/c1-2-12-8-16(9-13(12)14(17)18)15(19)20-10-11-6-4-3-5-7-11/h3-7H,2,8-10H2,1H3,(H,17,18)
InChIKey: HFBYGZWWAMZBID-UHFFFAOYSA-N
SMILES: N1(C(OCC2=CC=CC=C2)=O)CC(CC)=C(C(O)=O)C1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid Chemical Properties,Usage,Production

Uses

1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid is a pharmaceutical intermediate compound used in the synthesis of Upadacitinib, a Janus kinase (JAK) inhibitor approved by the FDA for the treatment of various chronic inflammatory conditions such as moderate-to-severe rheumatoid arthritis (RA), psoriatic arthritis, atopic dermatitis, ankylosing spondylitis, Crohn's disease, and ulcerative colitis.

1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid Suppliers

China 56 Global 56

Zibo Biopolar Rongchuang Pharmaceutical Co. Ltd.

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Jinan XuanDe Chemical Co., Ltd.

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View Lastest Price from 1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid manufacturers

Anhui Dexinjia Biopharm Co., Ltd

Product: 1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid 1869118-25-1
Price: US $100.00-10.00/KG
Min. Order: 1KG
Purity: less more than 98%
Supply Ability: 20tons
Release date: 2024-05-13

S&Y Biochem Co.,Ltd

Product: 1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid 1869118-25-1
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 100
Release date: 2024-08-01

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: Upadacitinib Impurity 41 1869118-25-1
Price: US $0.00/mg
Min. Order: 10mg
Purity: 0.98
Supply Ability: 10g
Release date: 2024-03-28

1869118-25-1, 1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acidRelated Search:

1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid

1H-Pyrrole-1,3-dicarboxylic acid, 4-ethyl-2,5-dihydro-, 1-(phenylmethyl) ester

Impurities in Upatinib 17

Upadacitinib Impurity 41

Upatinib impurity 41

8-((3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidin-3-yl)-6- ethyl-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-6-ium iodide

1869118-25-1