ChemicalBook > CAS DataBase List > (6R,S)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE

(6R,S)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE

Product Name: (6R,S)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE
CAS No.: 62989-33-7
Chemical Name: (6R,S)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE
Synonyms: sapropterin;BPH4;(6R)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE;R-THBP;Dapropterin;(6R,S)-BH4 2HCL;Sapropterin free base;Tetrahydro-6-biopterin;Sapropterin Impurity 24;(6R)-Tetrahydrobiopterin
CBNumber: CB5479898
Molecular Formula: C9H15N5O3
Formula Weight: 241.25
MOL File: 62989-33-7.mol

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(6R,S)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE Property

Boiling point:: 506.6±60.0 °C(Predicted)
Density: 1.89±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,2-8°C
pka: 5.05(at 25℃)

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
RTECS: UO3516500
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: CCH0008091
Product name: (R)-2-AMINO-6-((1R,2S)-1,2-DIHYDROXY-PROPYL)-5,6,7,8-TETRAHYDRO-1H-PTERIDIN-4-ONE
Purity: 98.00%
Packaging: 5G
Price: $1256.64
Updated: 2021/12/16

Crysdot

Product number: CD11084310
Product name: Sapropterin
Purity: 97%
Packaging: 1g
Price: $980
Updated: 2021/12/16

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(6R,S)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

Pk'5.05. UV maximum absorption (0.1 mol/L hydrochloric acid): 265 nm (ε14000). Sapropterin Dihydrochloride: C9H15N5O3?2HCl.[69056-38-8]. White crystal or crystalline powder, odorless, slightly acidic taste. Extremely soluble in water, more difficult to dissolve in methanol, very difficult to dissolve in ethanol, a few insoluble in ether. Melting point 245～246°C (decomposition). [α]D25-6.81.(C=0.665, 0.1mol/L hydrochloric acid).UV max absorption(2mol/L hydrochloric acid): 264nm(ε16770).

Uses

Treatment of mild-to-moderate phenylketonuria (PKU).

Definition

ChEBI: Sapropterin is a tetrahydropterin that is 2-amino-5,6,7,8-tetrahydropteridin-4(3H)-one in which a hydrogen at position 6 is substituted by a 1,2-dihydroxypropyl group (6R,1'R,2'S-enantiomer). It has a role as a coenzyme, a diagnostic agent, a human metabolite and a cofactor.

IC 50

Human Endogenous Metabolite

(6R,S)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Platinum balck 2-Amino-4-hydroxy-1H-pteridine

Preparation Products

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View Lastest Price from (6R,S)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Sapropterin 62989-33-7
Price: US $0.00-0.00/KG
Min. Order: 5g
Purity: 99%+
Supply Ability: 100 tons
Release date: 2019-12-25

Career Henan Chemical Co

Product: (6R,S)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE 62989-33-7
Price: US $0.10/KG
Min. Order: 1KG
Purity: 95%-99%
Supply Ability: 1kg; 50kg; 500kg
Release date: 2019-12-24

62989-33-7, (6R,S)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDERelated Search:

Benzoic acid Aprepitant Sapropterin Hydrochloride 4-AMINO-(6R)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE,4-AMINO-(6R)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE 4,5-Diamino-6-hydroxypyrimidine Tetrahydrobiopterin 2,4-Diamino-6-hydroxypyrimidine (6R,S)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE

4(1H)-PTERIDINONE, 2-AMINO-6-[(1R,2S)-1,2-DIHYDROXYPROPYL]-5,6,7,8-TETRAHYDRO-, (6R)-

2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-4(1H)-Pteridinone

(6R)-5,6,7,8-Tetrahydrobiopterin

sapropterin

(6R)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE

(6R,S)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE

(6R,S)-BH4 2HCL

(6R)-L-erythro-5,6,7,8-Tetrahydrobiopterin

(6R)-L-erythro-Tetrahydrobiopterin

(6R)-Tetrahydrobiopterin

4(1H)-Pteridinone, 2-amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-, [6R-[6R*(1R*,2S*)]]-

4(1H)-Pteridinone, 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-, (6R)- (9CI)

6b-5,6,7,8-Tetrahydro-L-biopterin

6R-Tetrahydro-L-biopterin

R-THBP

4(1H)-PTERIDINONE,2-AMINO-6-[(1R,2S)-1,2-DIHYDROXYPROPYL]-5,6,7,8-TETRAHYDRO

[6R-[6R^<*>^(1R^<*>^，2S^<*>^)]]-2-Amino-6-(1，2-dihydroxypropyl)-5，6，7，8-tetrahydro-4(1H)-ptefidinone

Tetrahydro-L-Biopterin free base

Dapropterin

(R)-2-amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydropteridin-4(3H)-one

(6R,S)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN

(6R,S)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE ISO 9001：2015 REACH

Sapropterin D3Q: What is Sapropterin D3 Q: What is the CAS Number of Sapropterin D3

SapropterinQ: What is Sapropterin Q: What is the CAS Number of Sapropterin Q: What is the storage condition of Sapropterin Q: What are the applications of Sapropterin

BPH4

Sapropterin free base

Tetrahydro-6-biopterin

Sapropterin dihydrchloride

Sapropterin Impurity 24

(6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-3,4,5,6,7,8-hexahydropteridin-4-one

62989-33-7