PORPHOBILINOGEN

Product Name: PORPHOBILINOGEN
CAS No.: 487-90-1
Chemical Name: PORPHOBILINOGEN
Synonyms: PBG;PORPHOBILINOGEN;porphobilinogen (synth.);5-(Aminomethyl)-4-(carboxymethyl)pyrrole-3-propionic acid;5-(aminomethyl)-4-(carboxymethyl)-1h-pyrrole-3-propanoicaci;5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propionic acid;5-[AMINOMETHYL]-4-[CARBOXYMETHYL]-1H-PYRROLE-3-PROPANOIC ACID;1H-Pyrrole-3-propanoic acid, 5-(aminomethyl)-4-(carboxymethyl)-;3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propionic acid;3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid
CBNumber: CB5481219
Molecular Formula: C10H14N2O4
Formula Weight: 226.23
MOL File: 487-90-1.mol

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PORPHOBILINOGEN Property

Melting point:: 174-177℃
Boiling point:: 479℃
Density: 1.421
Flash point:: 243℃
storage temp.: -20°C
solubility: Aqueous Base (Slightly), Acetonitrile (Slightly), DMSO (Slightly)
pka: 4.22±0.10(Predicted)
form: powder
color: light yellow to pink
Merck: 13,7681
BRN: 220051
EPA Substance Registry System: Porphobilinogen (487-90-1)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
F: 8-10

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P1134
Product name: Porphobilinogen
Purity: powder
Packaging: 1mg
Price: $110
Updated: 2024/03/01

Sigma-Aldrich

Product number: P1134
Product name: Porphobilinogen
Purity: powder
Packaging: 5mg
Price: $365
Updated: 2024/03/01

Sigma-Aldrich

Product number: P1134
Product name: Porphobilinogen
Purity: powder
Packaging: 10mg
Price: $688
Updated: 2024/03/01

Sigma-Aldrich

Product number: P1134
Product name: Porphobilinogen
Purity: powder
Packaging: 50mg
Price: $2130
Updated: 2024/03/01

TRC

Product number: P689500
Product name: Porphobilinogen
Packaging: 10mg
Price: $525
Updated: 2021/12/16

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PORPHOBILINOGEN Chemical Properties,Usage,Production

Uses

An intermediate in the biosynthesis of Heme, found in the urine of patients with acute porphyria.

Definition

ChEBI: Porphobilinogen is a dicarboxylic acid that is pyrole bearing aminomethyl, carboxymethyl and 2-carboxyethyl substituents at positions 2, 3 and 4 respectively. It has a role as a metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a member of pyrroles, a dicarboxylic acid and an aralkylamino compound. It is a conjugate acid of a porphobilinogen(1-).

Biochem/physiol Actions

Intermediate in the biosynthesis of heme.

Purification Methods

Porphobilinogen recrystallises as the monohydrate (pink crystals) from dilute NH4 OAc solutions of pH 4, and is dried in vacuo. The hydrochloride monohydrate has m 165-170o(dec) (from dilute HCl). [Jackson & MacDonald Can J Chem 35 715 1957, Westall Nature 170 614 1952, Bogarad J Am Chem Soc 75 3610 1953, Beilstein 22/14 V 210.]

PORPHOBILINOGEN Preparation Products And Raw materials

Raw materials

Preparation Products

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487-90-1, PORPHOBILINOGENRelated Search:

porphobilinogen oxygenase Porphobilinogen synthase, 5-Aminolevulinate Hydrolyase (adding 5-aminolevulinate and cyclizing),PORPHOBILINOGEN SYNTHASE 3-ETHYL-1H-PYRROLE (1H-PYRROL-2-YL)METHANAMINE 2,4-Dimethyl-3-ethyl-1H-pyrrole 3,4-DIETHYLPYRROLE PORPHOBILINOGEN 2,4-Dimethylpyrrole 3-(PYRROL-3-YL)-PROPIONIC ACID 3-METHYLPYRROLE 5-Methyl-pyrrole-3-propionic acid (PYRROL-3-YL)-ACETIC ACID 3,4-DIMETHYLPYRROLE

PBG

5-(aminomethyl)-4-(carboxymethyl)-1h-pyrrole-3-propanoicaci

PORPHOBILINOGEN

porphobilinogen (synth.)

5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propionic acid

3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid

5-[AMINOMETHYL]-4-[CARBOXYMETHYL]-1H-PYRROLE-3-PROPANOIC ACID

5-(Aminomethyl)-4-(carboxymethyl)pyrrole-3-propionic acid

3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propionic acid

1H-Pyrrole-3-propanoic acid, 5-(aminomethyl)-4-(carboxymethyl)-

487-90-1

C10H14N2O4xH2O

Biochemicals and Reagents

BioChemical

Porphobilinogen deaminase

Porphyrin

Substrates by Enzyme

Metabolomics

Metabolic Pathways

Metabolites and Cofactors on the Metabolic Pathways Chart

Enzymes, Inhibitors, and Substrates

Enzyme Substrates

organic building block

Porphyrins

Precursers

Amines

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals

Elisa Kit-plant ELISA Kit