PORPHOBILINOGEN
- Product Name
- PORPHOBILINOGEN
- CAS No.
- 487-90-1
- Chemical Name
- PORPHOBILINOGEN
- Synonyms
- PBG;PORPHOBILINOGEN;porphobilinogen (synth.);5-(Aminomethyl)-4-(carboxymethyl)pyrrole-3-propionic acid;5-(aminomethyl)-4-(carboxymethyl)-1h-pyrrole-3-propanoicaci;5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propionic acid;5-[AMINOMETHYL]-4-[CARBOXYMETHYL]-1H-PYRROLE-3-PROPANOIC ACID;1H-Pyrrole-3-propanoic acid, 5-(aminomethyl)-4-(carboxymethyl)-;3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propionic acid;3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid
- CBNumber
- CB5481219
- Molecular Formula
- C10H14N2O4
- Formula Weight
- 226.23
- MOL File
- 487-90-1.mol
PORPHOBILINOGEN Property
- Melting point:
- 174-177℃
- Boiling point:
- 479℃
- Density
- 1.421
- Flash point:
- 243℃
- storage temp.
- -20°C
- solubility
- Aqueous Base (Slightly), Acetonitrile (Slightly), DMSO (Slightly)
- pka
- 4.22±0.10(Predicted)
- form
- powder
- color
- light yellow to pink
- Merck
- 13,7681
- BRN
- 220051
- EPA Substance Registry System
- Porphobilinogen (487-90-1)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P1134
- Product name
- Porphobilinogen
- Purity
- powder
- Packaging
- 1mg
- Price
- $110
- Updated
- 2024/03/01
- Product number
- P1134
- Product name
- Porphobilinogen
- Purity
- powder
- Packaging
- 5mg
- Price
- $365
- Updated
- 2024/03/01
- Product number
- P1134
- Product name
- Porphobilinogen
- Purity
- powder
- Packaging
- 10mg
- Price
- $688
- Updated
- 2024/03/01
- Product number
- P1134
- Product name
- Porphobilinogen
- Purity
- powder
- Packaging
- 50mg
- Price
- $2130
- Updated
- 2024/03/01
- Product number
- 287240
- Product name
- Porphobilinogen
- Packaging
- 25mg
- Price
- $955
- Updated
- 2021/12/16
PORPHOBILINOGEN Chemical Properties,Usage,Production
Uses
An intermediate in the biosynthesis of Heme, found in the urine of patients with acute porphyria.
Definition
ChEBI: Porphobilinogen is a dicarboxylic acid that is pyrole bearing aminomethyl, carboxymethyl and 2-carboxyethyl substituents at positions 2, 3 and 4 respectively. It has a role as a metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a member of pyrroles, a dicarboxylic acid and an aralkylamino compound. It is a conjugate acid of a porphobilinogen(1-).
Biochem/physiol Actions
Intermediate in the biosynthesis of heme.
Purification Methods
Porphobilinogen recrystallises as the monohydrate (pink crystals) from dilute NH4 OAc solutions of pH 4, and is dried in vacuo. The hydrochloride monohydrate has m 165-170o(dec) (from dilute HCl). [Jackson & MacDonald Can J Chem 35 715 1957, Westall Nature 170 614 1952, Bogarad J Am Chem Soc 75 3610 1953, Beilstein 22/14 V 210.]