UAMC-3203
- Product Name
- UAMC-3203
- CAS No.
- 2271358-64-4
- Chemical Name
- UAMC-3203
- Synonyms
- UAMC-3203;(S)-L-Cystine-;UAMC3203;UAMC 3203;inhibit,Ferroptosis,Inhibitor,UAMC-3203;4-(cyclohexylamino)-3-[(phenylmethyl)amino]-N-[2-(1-piperazinyl)ethyl]-benzene;Benzenesulfonamide, 4-(cyclohexylamino)-3-[(phenylmethyl)amino]-N-[2-(1-piperazinyl)ethyl]-
- CBNumber
- CB54843929
- Molecular Formula
- C25H37N5O2S
- Formula Weight
- 471.66
- MOL File
- 2271358-64-4.mol
UAMC-3203 Property
- Boiling point:
- 668.3±65.0 °C(Predicted)
- Density
- 1.214±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Ethanol: Soluble
- form
- A crystalline solid
- pka
- 12.27±0.50(Predicted)
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 26525
- Product name
- UAMC-3203
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 26525
- Product name
- UAMC-3203
- Packaging
- 5mg
- Price
- $109
- Updated
- 2024/03/01
- Product number
- 26525
- Product name
- UAMC-3203
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $153
- Updated
- 2024/03/01
- Product number
- 26525
- Product name
- UAMC-3203
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $305
- Updated
- 2024/03/01
- Product number
- 26525
- Product name
- UAMC-3203
- Packaging
- 500μg
- Price
- $27
- Updated
- 2021/12/16
UAMC-3203 Chemical Properties,Usage,Production
Biological Activity
UAMC-3203 is a ferroptosis inhibitor with IC50 of 10 nM in IMR-32 neuroblastoma cells.
in vitro
UAMC-3203 was incubated with human microsomes or rat microsomes, and the T 1/2 were 20.5 h and 16.5 h, respectively. When co-incubated with mouse microsomes, UAMC-3203 showed relatively poor stability, with a T 1/2 of 3.46 h.
in vivo
In mice, UAMC-3203 can significantly reduce the plasma concentration of lactate dehydrogenase. After administration, it is rapidly removed from the blood and enters various tissues. Significant levels of UAMC-3203 were detected in the tissues tested, such as liver, kidney and lung.
target
| Target | Value |
| Ferroptosis (IMR-32 neuroblastoma cells) | < td style="border-bottom: 1px dotted #ccc;padding: 5px;"> 10 nM
UAMC-3203 Preparation Products And Raw materials
Raw materials
Preparation Products
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