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HC≡C-CH2-PEG3-SH

Product Name
HC≡C-CH2-PEG3-SH
CAS No.
1412905-18-0
Chemical Name
HC≡C-CH2-PEG3-SH
Synonyms
HC≡C-CH2-PEG3-SH;Propargyl-PEG3-SH;Ethanethiol, 2-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-
CBNumber
CB54868344
Molecular Formula
C9H16O3S
Formula Weight
204.29
MOL File
1412905-18-0.mol
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HC≡C-CH2-PEG3-SH Property

Boiling point:
286.2±30.0 °C(Predicted)
Density 
1.053±0.06 g/cm3(Predicted)
pka
9?+-.0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

purepeg
Product number
437903
Product name
HS-PEG3-Propyne
Purity
min.95%
Packaging
250mg
Price
$127
Updated
2021/12/16
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HC≡C-CH2-PEG3-SH Chemical Properties,Usage,Production

Biological Activity

Propargyl-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

HC≡C-CH2-PEG3-SH Preparation Products And Raw materials

Raw materials

Preparation Products

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HC≡C-CH2-PEG3-SH Suppliers

Xi'an Confluore Biological Technology Co., Ltd.
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+86-156-80926068 +86-15680926068
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1924344760@qq.com
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China
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Alfa Chemistry
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TargetMol Chemicals Inc.
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+1-781-999-5354 +1-00000000000
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marketing@targetmol.com
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840 15801484223;
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psaitong@jm-bio.com
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China
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Affinity(Wuhan)Ltd.
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15841022315
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sales@affinitytech.cn
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China
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Zhengzhou Converging Chemical Co. LTD
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0371-0371-53399770 18037166334
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2853031800@qq.com
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Shochem (Shanghai) Co.,Ltd
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meijia.sun@zheng-tuo.com
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1412905-18-0, HC≡C-CH2-PEG3-SHRelated Search:


  • HC≡C-CH2-PEG3-SH
  • Propargyl-PEG3-SH
  • Ethanethiol, 2-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-
  • 1412905-18-0