(-)-10-(3-[DIMETHYLAMINO]-2-METHYLPROPYL)-2-METHOXY-PHENOTHIAZINE MALEATE SALT

Product Name: (-)-10-(3-[DIMETHYLAMINO]-2-METHYLPROPYL)-2-METHOXY-PHENOTHIAZINE MALEATE SALT
CAS No.: 60-99-1
Chemical Name: (-)-10-(3-[DIMETHYLAMINO]-2-METHYLPROPYL)-2-METHOXY-PHENOTHIAZINE MALEATE SALT
Synonyms: XP 03;rp7044;C07192;Nirvan;skf5116;Sinogan;cl36467;cl39743;cl53212;dedoran
CBNumber: CB5488571
Molecular Formula: C19H24N2OS
Formula Weight: 328.47
MOL File: 60-99-1.mol

More

Less

(-)-10-(3-[DIMETHYLAMINO]-2-METHYLPROPYL)-2-METHOXY-PHENOTHIAZINE MALEATE SALT Property

Melting point:: 117°C
Boiling point:: 468.0±45.0 °C(Predicted)
Density: 1.0897 (rough estimate)
refractive index: 1.5950 (estimate)
storage temp.: Store at -20°C
solubility: Chloroform (Slightly), Methanol (Very Slightly)
form: Solid
pka: 9.32±0.28(Predicted)
color: White to Off-White
Water Solubility: 20mg/L(25 ºC)

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 20/21/22
Safety Statements: 36
RIDADR: 3249
RTECS: SO6125000
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 2934302300
Toxicity: LD50 oral in rat: 1100mg/kg

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 1415006
Product name: Methotrimeprazine maleate salt
Packaging: 200mg
Price: $276
Updated: 2024/03/01

TRC

Product number: M260770
Product name: (R)-Methotrimeprazine
Packaging: 10mg
Price: $1470
Updated: 2021/12/16

ChemScene

Product number: CS-0013678
Product name: Levomepromazine
Purity: 99.98%
Packaging: 10mg
Price: $85
Updated: 2021/12/16

ChemScene

Product number: CS-0013678
Product name: Levomepromazine
Purity: 99.98%
Packaging: 50mg
Price: $250
Updated: 2021/12/16

ChemScene

Product number: CS-0013678
Product name: Levomepromazine
Purity: 99.98%
Packaging: 100mg
Price: $420
Updated: 2021/12/16

More

Less

(-)-10-(3-[DIMETHYLAMINO]-2-METHYLPROPYL)-2-METHOXY-PHENOTHIAZINE MALEATE SALT Chemical Properties,Usage,Production

Originator

Levoprome ,Lederle,US,1966

Uses

(R)-Methotrimeprazine acts as an analgesic agent.

Definition

ChEBI: A member of the class of phenothiazines that is 10H-phenothiazine substituted by a (2R)-3-(dimethylamino)-2-methylpropyl group and a methoxy group at positions 10 and 2 respectively.

Manufacturing Process

95% sodamide (2.33 g) is added to a boiling solution of 3- methoxyphenthiazine (12 g) in anhydrous xylene (150 cc) and the mixture is heated with agitation under reflux for 1? hours. A solution of 1- dimethylamino-2-methyl-3-chloropropane (8.2 g) in anhydrous xylene (90 cc) is then run in over a period of 45 minutes while the reaction temperature is maintained and heating under reflux is continued for 18 hours.
After cooling, the reaction mixture is agitated with a mixture of water (40 cc) and a normal solution of methanesulfonic acid (70 cc), the xylene layer is removed and the acid liquors are washed with ether (200 cc). The aqueous phase is then made alkaline with sodium hydroxide (d = 1.33; 10 cc) and the liberated base is extracted with ether. The ethereal solution is dried over anhydrous potassium carbonate and concentrated at normal pressure. On distillation of the residue under reduced pressure 3-(3-methoxy-10- phenthiazinyl)-2-methyl-1-dimethylaminopropane (11.3 g) is obtained, MP 103°C, BP 182° to 191°C/0.15 mm Hg. The hydrochloride prepared in isopropanol melts at about 90°C.

brand name

Levoprome (Immunex).

Therapeutic Function

Analgesic

(-)-10-(3-[DIMETHYLAMINO]-2-METHYLPROPYL)-2-METHOXY-PHENOTHIAZINE MALEATE SALT Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(-)-10-(3-[DIMETHYLAMINO]-2-METHYLPROPYL)-2-METHOXY-PHENOTHIAZINE MALEATE SALT Suppliers

Canada 1 China 29 France 1 Germany 1 India 2 Italy 1 South Korea 1 Switzerland 2 United Kingdom 1 United States 14 Global 53

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9823
Advantage: 79

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3421
Advantage: 58

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9911
Advantage: 50

Chizhou Kailong Import and Export Trade Co., Ltd.

Tel
Fax: -
Email: xg01_gj@163.com
Country: China
ProdList: 9503
Advantage: 50

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 29118
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: 571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: CHINA
ProdList: 52867
Advantage: 58

AFINE CHEMICALS LIMITED

Tel: 0571-85134551
Fax: 008657185134895
Email: info@afinechem.com
Country: CHINA
ProdList: 15377
Advantage: 58

Hubei Jusheng Technology Co.,Ltd.

Tel: 18871490254
Fax: 027-59599243
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 28180
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11289
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 15850508050
Fax: 025-85563444
Email: rose.shi@synzest.com
Country: China
ProdList: 9287
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44941
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 13675144456
Fax: 025-85563444
Email: sean.lv@synzest.com
Country: China
ProdList: 10787
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223
Email: psaitong@jm-bio.com
Country: China
ProdList: 29834
Advantage: 58

InvivoChem

Tel: 13549236410
Email: sales@invivochem.cn
Country: China
ProdList: 6712
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 18351873721
Email: helen.zhang@synzest.com
Country: China
ProdList: 8298
Advantage: 58

Shaanxi DIDU pharmaceutical and Chemical Co., Ltd

Tel: 15229059051
Email: 1027@dideu.com
Country: China
ProdList: 9921
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24131
Advantage: 58

Shanghai Saikerui Biotechnology Co. , Ltd.

Tel: 021-58000709 15900491054
Email: info@scrbio.com
Country: China
ProdList: 9260
Advantage: 58

Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd

Tel: 18162595016
Email: 3287908757@qq.com
Country: China
ProdList: 9886
Advantage: 58

Shanghai Acmec Biochemical Technology Co., Ltd.

Tel: +undefined18621343501
Email: product@acmec-e.com
Country: China
ProdList: 33349
Advantage: 58

ZHEJIANG JIUZHOU CHEM CO., LTD

Tel: +86-0576225566889 +86-13454675544
Email: admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com
Country: China
ProdList: 20000
Advantage: 58

Xiamen Wonderful Bio Technology Co., Ltd.

Tel: +8613043004613
Email: Sara@xmwonderfulbio.com
Country: China
ProdList: 305
Advantage: 58

GIHI CHEMICALS CO.,LIMITED

Tel: +8618058761490
Email: info@gihichemicals.com
Country: China
ProdList: 50000
Advantage: 58

Shaanxi Didu New Materials Co. Ltd

Tel: +86-89586680 +86-13289823923
Email: 1026@dideu.com
Country: China
ProdList: 9116
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6846
Advantage: 58

More

Less

View Lastest Price from (-)-10-(3-[DIMETHYLAMINO]-2-METHYLPROPYL)-2-METHOXY-PHENOTHIAZINE MALEATE SALT manufacturers

Xiamen Wonderful Bio Technology Co., Ltd.

Product: Levomepromazine 60-99-1
Price: US $66.00/kg
Min. Order: 1kg
Purity: 99.98%
Supply Ability: 1
Release date: 2023-06-08

Dideu Industries Group Limited

Product: (-)-10-(3-[DIMETHYLAMINO]-2-METHYLPROPYL)-2-METHOXY-PHENOTHIAZINE MALEATE SALT 60-99-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-07-23

60-99-1, (-)-10-(3-[DIMETHYLAMINO]-2-METHYLPROPYL)-2-METHOXY-PHENOTHIAZINE MALEATE SALTRelated Search:

2-Methoxyphenothiazine Phenothiazine (-)-10-(3-[DIMETHYLAMINO]-2-METHYLPROPYL)-2-METHOXY-PHENOTHIAZINE MALEATE SALT Methotrimeprazine Sulfoxide

methotrimeprazine maleate

rp7044

Sinogan

Sinogan-Debil

SK&F 5116

SKF 5116

skf5116

Tisercin

Veractil

(bR)-2-Methoxy-N,N,b-trimethyl-10H-phenothiazine-10-propanamine

Levoprom

10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,.beta.-trimethyl-, (.beta.R)-

10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,b-trimethyl-, (bR)- (9CI)

10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,b-trimethyl-, (R)-

NSC 226516

Phenothiazine, 10-[3-(dimethylamino)-2-methylpropyl]-2-methoxy-, (-)- (8CI)

XP 03

(R)-2-Methoxy-N,N,-trimethyl-10H-phenothiazine-10-propanamine

C07192

Methotrimeprazine-d3 maleate

Methotrimeprazine (200 mg)

10H-Phenothiazine-10-propanaMine, 2-Methoxy-N,N,β-triMethyl-, (βR)-

(2R)-3-(2-methoxyphenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine

(-)-10-(3-[DIMETHYLAMINO]-2-METHYLPROPYL)-2-METHOXY-PHENOTHIAZINE MALEATE SALT

METHOTRIMEPRAZINE MALEATE SALT

(-)-10-(3-(Dimethylamino)-2-methylpropyl)-2-methoxyphenothiazine

(-)-3-(2-Methoxyphenothiazin-10-yl)-2-methylpropyldimethylamine

(-)-phenothiazin

10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,beta-trimethyl-, (-)-

10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,beta-trimethyl-, (R)-

2-Methoxytrimeprazine

3-(2-Methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethyl-1-propanamine

7044 R.P.

arc-vi-c-5

bayer1213

CL 36467

CL 39743

cl36467

cl39743

cl53212

dedoran

Hirnamin

hirnamine

Levomeprazine

Levomepromazin

Levomepromazine

Levomepropazine

Levopromazine

levopromazioni

Levoprome

Levopromethazine

Levotomin

Mepromazine

methotrimeprazine

methoxytrimeprazine

milezin

minozinan

n,beta-trimethyl-2-methoxy-(r)-10h-phenothiazine-10-propanamin