ChemicalBook > CAS DataBase List > 5-METHOXY-2-METHYL-3-INDOLEACETIC ACID

5-METHOXY-2-METHYL-3-INDOLEACETIC ACID

Product Name
5-METHOXY-2-METHYL-3-INDOLEACETIC ACID
CAS No.
2882-15-7
Chemical Name
5-METHOXY-2-METHYL-3-INDOLEACETIC ACID
Synonyms
NSC 97026;5-MeO,2-Me-IAA;VITAS-BB TBB000392;TIMTEC-BB SBB003362;Indomethacin USP RC A;Acemetacin Impurity 3;Indomethacin Impurity 13;Indometacin EP Impurity B;Indomethacin EP Impurity B;De(chlorobenzoyl)indomethacin.
CBNumber
CB5488768
Molecular Formula
C12H13NO3
Formula Weight
219.24
MOL File
2882-15-7.mol
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5-METHOXY-2-METHYL-3-INDOLEACETIC ACID Property

Melting point:
161-163 °C (lit.)
Boiling point:
360.05°C (rough estimate)
Density 
1.1825 (rough estimate)
refractive index 
1.5270 (estimate)
storage temp. 
2-8°C
solubility 
methanol: soluble
pka
4.22±0.30(Predicted)
form 
Crystalline Powder
color 
Off-white to light yellow or light beige
CAS DataBase Reference
2882-15-7(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2770
Product name
Indomethacin Related Compound A
Purity
Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 50?mg
Packaging
50MG
Price
$621.3
Updated
2025/07/31
Sigma-Aldrich
Product number
105171
Product name
5-Methoxy-2-methyl-3-indoleacetic acid
Purity
98%
Packaging
1g
Price
$110
Updated
2025/07/31
Sigma-Aldrich
Product number
105171
Product name
5-Methoxy-2-methyl-3-indoleacetic acid
Purity
98%
Packaging
5g
Price
$228.2
Updated
2025/07/31
Sigma-Aldrich
Product number
1417113
Product name
Indomethacin Related Compound A
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
25mg
Price
$1300
Updated
2025/07/31
TRC
Product number
D288845
Product name
N-DeschlorobenzoylIndomethacin
Packaging
1g
Price
$120
Updated
2021/12/16
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5-METHOXY-2-METHYL-3-INDOLEACETIC ACID Chemical Properties,Usage,Production

Chemical Properties

slightly yellow fine crystalline powder

Uses

  • Reactant for preparation of antimalarial agents
  • Reactant for preparation of ndomethacin analogs as cyclooxygenase and lipoxygenase inhibitors with antiinflammatory activity
  • Reactant for preparation of [123I]-indomethacin derivatives as COX-2 targeted imaging agents
  • Reactant for preparation of histone deacetylase inhibitors
  • Reactant for preparation of 2,N6,5′-substituted adenosine derivatives as ligands for A2B adenosine receptor
  • Reactant for preparation of prostaglandin D2 receptor antagonist

Uses

5-Methoxy-2-methyl-3-indoleacetic acid was used for quantitative determination of indomethacin and its major impurities in suppository and capsule formulations by HPLC. 5-Methoxy-2-methyl-3-indoleacetic acid was used in a study to develop fast, sensitive and simultaneous determination of metabolites of serotonin using liquid chromatography with mass spectrometric detection.

Uses

A metabolite of Indomethacin.

Definition

ChEBI: N-Deschlorobenzoyl indomethacin is a member of indole-3-acetic acids.

General Description

5-Methoxy-2-methyl-3-indoleacetic acid is hydrolysis product of indomethacin.

5-METHOXY-2-METHYL-3-INDOLEACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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5-METHOXY-2-METHYL-3-INDOLEACETIC ACID Suppliers

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View Lastest Price from 5-METHOXY-2-METHYL-3-INDOLEACETIC ACID manufacturers

Career Henan Chemical Co
Product
5-METHOXY-2-METHYL-3-INDOLEACETIC ACID 2882-15-7
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2019-12-30

2882-15-7, 5-METHOXY-2-METHYL-3-INDOLEACETIC ACIDRelated Search:

1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYL-3-INDOLEACETIC ACID 2-Methylindole 4-Chloro-N-(4-Methoxyphenyl)benzaMide, 97% 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-hydroxypropyl ester 4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid 4-Chlorobenzoic acid Benzoic acid, 4-chloro-, 2,3-dihydroxypropyl ester 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-Methoxy-2-Methyl-, ethyl ester 1H-INDOLE-3-ACETICACID,1-(3-CHLOROBENZOYL)-5-METHOXY-2-METHYL 2-(4-METHOXYPHENYL)HYDRAZINESULFONIC ACID SODIUM SALT MONOHYDRATE IndoMethacin DiaMide methyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-,2,3-d ihydroxypropyl ester Indometacin EP Impurity G Indometacin EP Impurity D Indometacin Impurity 17 Methanone, (4-chlorophenyl)[2,6-dichloro-4-(hydroxymethyl)phenyl]- Indometacin Impurity 18

  • 5-METHOXY-2-METHYL INDOLE ACETIC ACID
  • Indomethacin impurity 1/5-methoxy-2-methyl-1H-Indole-3-acetic acid
  • Indomethacin EP Impurity B
  • Indometacin Impurit Ⅰ:5-Methoxy-2-Methyl-3-IndoleaceticAcid
  • Indomethacin USP RC A
  • 5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID
  • (5-METHOXY-2-METHYL-1H-INDOL-3-YL)-ACETIC ACID
  • 5-METHOXY-2-METHYL-3-INDOLEACETIC ACID
  • 5-methoxy-2-methylindol-3-ylacetic acid
  • De(chlorobenzoyl)indomethacin.
  • 5-methoxy-methylindoleacetic acid
  • 5-METHOXY-2-METHYL-3-INDOLEACETIC ACID 98%
  • 5-MeO,2-Me-IAA
  • (2-Methyl-5-methoxy-1H-indole-3-yl)acetic acid
  • 5-Methoxy-2-methyl-1H-indole-3-acetic acid
  • N-Deschlorobenzoylindomethacin
  • 5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID (5MeO2MeIAA)
  • 5-Methoxy-2-methyl-3-indoleacetic acid,98%
  • TIMTEC-BB SBB003362
  • VITAS-BB TBB000392
  • 1H-Indole-3-aceticacid, 5-Methoxy-2-Methyl-
  • 5-Methoxy-2-Methyl-3-indoleacetic acid, 98% 1GR
  • 2-Methyl-5-Methoxy-3-indolylacetic Acid
  • N-Des(4-chlorobenzoyl)indoMethacin
  • NSC 97026
  • IndoMethacin Related CoMpound A
  • Indometacin EP Impurity B
  • N-deschlorobenzyl Indomethacin
  • Acemetacin Impurity 3
  • Indomethacin Impurity 13
  • Indomethacin EP Impurity B/ Indomethacin Related Compound A (Indomethacin N-Deschlorobenzoyl Impurity)
  • Indomethacin Related Compound A (2-(5-methoxy-2-methyl-1H-indol-3-yl)acetic acid) (1417113)
  • Acemetacin Impurity 2/Indomethacin EP impurity B
  • 5-Methoxy-2-methyl-3-indolylacetic Acid
  • Indomethacin (Indometacin) EP Impurity B (Indomethacin USP Related Compound A)
  • 2-(5-methoxy-2-methyl-1H-indol-3-yl)acetic acid - [M72478]
  • Indometacin Imp.B (EP): (5-methoxy-2-Methyl-1H-indol-2-yl) acetic acid
  • 2882-15-7
  • 21924
  • Heterocyclic Building Blocks
  • Indoles
  • Building Blocks
  • Heterocycles
  • Indole Derivatives
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Heterocyclic Compounds
  • Building Blocks
  • Heterocyclic Building Blocks
  • Indoles
  • Indoles and derivatives