6,7-DIHYDRO-5H-1-PYRIDIN-5-ONE
- Product Name
- 6,7-DIHYDRO-5H-1-PYRIDIN-5-ONE
- CAS No.
- 28566-14-5
- Chemical Name
- 6,7-DIHYDRO-5H-1-PYRIDIN-5-ONE
- Synonyms
- 6,7-DIHYDRO-5H-CYCLOPENTA[B]PYRIDIN-5-ONE;112208;6,7-DIHYDRO-5H-1-PYRIDIN-5-ONE;6,7-DIHYDRO-5H-[1]PYRINDIN-5-ONE;6H,7H-cyclopenta[b]pyridin-5-one;5H,6H,7H-cyclopenta[b]pyridin-5-one;6,7-dihydrocyclopenta[b]pyridin-5-one;6,7-Dihydro-5-oxo-5H-cyclopenta[b]pyridine;5H-cyclopenta[b]pyridine-5-one,6,7-dihydro-;5H-Cyclopenta[b]pyridin-5-one, 6,7-dihydro-
- CBNumber
- CB5495694
- Molecular Formula
- C8H7NO
- Formula Weight
- 133.15
- MOL File
- 28566-14-5.mol
6,7-DIHYDRO-5H-1-PYRIDIN-5-ONE Property
- Melting point:
- 64-66 °C
- Boiling point:
- 125 °C(Press: 9 Torr)
- Density
- 1.230±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 3.47±0.20(Predicted)
- Appearance
- Gray to brown Solid
- InChI
- InChI=1S/C8H7NO/c10-8-4-3-7-6(8)2-1-5-9-7/h1-2,5H,3-4H2
- InChIKey
- LMEREVKJVWUGJI-UHFFFAOYSA-N
- SMILES
- C12CCC(=O)C1=CC=CN=2
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D679750
- Product name
- 6,7-Dihydro-5H-cyclopenta[b]pyridin-5-one
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- D679750
- Product name
- 6,7-Dihydro-5H-cyclopenta[b]pyridin-5-one
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FD52106
- Product name
- 6,7-Dihydro-5H-1-pyridin-5-one
- Packaging
- 100mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- FD52106
- Product name
- 6,7-Dihydro-5H-1-pyridin-5-one
- Packaging
- 250mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- FD52106
- Product name
- 6,7-Dihydro-5H-1-pyridin-5-one
- Packaging
- 500mg
- Price
- $200
- Updated
- 2021/12/16
6,7-DIHYDRO-5H-1-PYRIDIN-5-ONE Chemical Properties,Usage,Production
Synthesis
533-37-9
28566-14-5
The general procedure for the synthesis of 6,7-dihydrocyclopenta[b]pyridin-5-one using 2,3-cyclopentenopyridine as starting material was as follows: 0.883 mg of Mn(OTf)2 (0.5 mol%), 60 mg of 2,3-cyclopentenopyridine, 0.35 g of 65% aqueous TBHP and 2.5 mL of water were added sequentially to 25 mL of a round bottomed flask. The reaction system was stirred in air at room temperature for 24 hours. Upon completion of the reaction, the reaction mixture was extracted with ethyl acetate (3 × 5 mL), the organic phases were combined and dried over anhydrous sodium sulfate. After filtration, the solvent was removed by distillation under reduced pressure. The crude product was purified by silica gel column chromatography using petroleum ether and ethyl acetate (5:1, v/v) as eluent to afford 60.5 mg of 6,7-dihydro-5H-cyclopentadieno[b]pyridin-5-one as a light yellow solid in 91% yield.
References
[1] Patent: CN105669548, 2016, A. Location in patent: Paragraph 0027; 0028
[2] Angewandte Chemie - International Edition, 2018, vol. 57, # 15, p. 4078 - 4082
[3] Angew. Chem., 2018, vol. 130, # 15, p. 4142 - 4146,5
[4] Chinese Journal of Catalysis, 2016, vol. 37, # 8, p. 1216 - 1221
[5] Organic Letters, 2018, vol. 20, # 7, p. 1987 - 1990
6,7-DIHYDRO-5H-1-PYRIDIN-5-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6,7-DIHYDRO-5H-1-PYRIDIN-5-ONE manufacturers
- Product
- 6,7-Dihydro-5H-cyclopenta[b]pyridin-5-one 28566-14-5
- Price
- US $2.20-8.80/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-17
- Product
- 6,7-DIHYDRO-5H-1-PYRIDIN-5-ONE 28566-14-5
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-13
- Product
- 5H-Cyclopenta[b]pyridin-5-one,6,7-dihydro- 28566-14-5
- Price
- US $0.00/Kg/Drum
- Min. Order
- 20Kg/Drum
- Purity
- 97%
- Supply Ability
- 10 Metric Ton/Month
- Release date
- 2020-04-17