3,3-DIMETHYL-1-BUTANOL

Product Name: 3,3-DIMETHYL-1-BUTANOL
CAS No.: 624-95-3
Chemical Name: 3,3-DIMETHYL-1-BUTANOL
Synonyms: 3,3-dimethylbutan-1-ol;1-Butanol, 3,3-dimethyl-;NEOHEXANOL;Dimethylbutanol;Neotame Impurity 2;3,3-Dimethylbutanol;3,3-dimethyl-1-butano;3,3-DIMETHYL-1-BUTANOL;Neohexanol|||DMB|||DMB;3,3-dimethyl-butan-1-ol
CBNumber: CB5496686
Molecular Formula: C6H14O
Formula Weight: 102.17
MOL File: 624-95-3.mol

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3,3-DIMETHYL-1-BUTANOL Property

Melting point:: −60 °C(lit.)
Boiling point:: 143 °C(lit.)
Density: 0.844 g/mL at 25 °C(lit.)
refractive index: n20/D 1.414(lit.)
Flash point:: 118 °F
storage temp.: 2-8°C
form: clear liquid
pka: 15.17±0.10(Predicted)
color: Colorless to Almost colorless
Water Solubility: Slightly soluble in water.
BRN: 1731466
InChI: 1S/C6H14O/c1-6(2,3)4-5-7/h7H,4-5H2,1-3H3
InChIKey: DUXCSEISVMREAX-UHFFFAOYSA-N
SMILES: CC(C)(C)CCO
CAS DataBase Reference: 624-95-3(CAS DataBase Reference)
NIST Chemistry Reference: 1-Butanol, 3,3-dimethyl-(624-95-3)
EPA Substance Registry System: 3,3-Dimethyl-1-butanol (624-95-3)

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Safety

Risk Statements: 10
Safety Statements: 23-24/25-23/24/25
RIDADR: UN 1987 3/PG 3
WGK Germany: 3
TSCA: TSCA listed
HazardClass: 3.2
PackingGroup: III
HS Code: 29051990
Storage Class: 3 - Flammable liquids
Hazard Classifications: Flam. Liq. 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 183105
Product name: 3,3-Dimethyl-1-butanol
Purity: 98%
Packaging: 10g
Price: $132.05
Updated: 2025/07/31

Sigma-Aldrich

Product number: 183105
Product name: 3,3-Dimethyl-1-butanol
Purity: 98%
Packaging: 50g
Price: $349.6
Updated: 2025/07/31

TCI Chemical

Product number: D1333
Product name: 3,3-Dimethyl-1-butanol
Purity: >95.0%(GC)
Packaging: 5mL
Price: $36
Updated: 2025/07/31

TCI Chemical

Product number: D1333
Product name: 3,3-Dimethyl-1-butanol
Purity: >95.0%(GC)
Packaging: 25mL
Price: $114
Updated: 2025/07/31

GFS CHEMICALS

Product number: 11071
Product name: 3,3-DIMETHYL-1-BUTANOL
Packaging: 10g
Price: $92.86
Updated: 2021/12/16

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3,3-DIMETHYL-1-BUTANOL Chemical Properties,Usage,Production

Chemical Properties

colorless liqui

Uses

3,3-Dimethyl-1-butanol, is an organic building block used for the synthesis of various pharmaceutical compounds. It is an important intermediate in the synthesis of Neotame, an enhanced sweetening agent.

General Description

3,3-Dimethyl-1-butanol is a glass forming material. The molecular dynamics of 3,3-dimethyl-1-butanol was studied.

Synthesis

3,3-Dimethyl-1-butyrate can be obtained by first preparing 3,3-dimethylbutyl sulfate from tert-butanol and ethylene, and then reacting it with sodium hydroxide.

in vivo

3,3-Dimethyl-1-butanol (1% DMB soluble in water; p.o.; 6 weeks) significantly reduces the cardiac hypertrophy and fibrosis in heart failure (HF) mice^[1].
3,3-Dimethyl-1-butanol (0.2% and 1.0% DMB soluble in water; p.o.; 21 d) increases the serum TMAO level with dose-dependent manner in ICR mice. 3,3-Dimethyl-1-butanol has been proved that the interaction between the gut and the brain has a regulatory effect on social behavior^[2].
3,3-Dimethyl-1-butanol (1.0% DMB soluble in water; p.o.; gestation period and suckling period) prevents the 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced hypertension in offspring of pregnant Sprague-Dawley rats^[3].

Animal Model:	C57BL6/J male mice (8-10 weeks old) with heart failure^[1].
Dosage:	1% DMB soluble in water.
Administration:	Oral gavage; 6 weeks.
Result:	Reduced the plasma trimethylamine N-oxide (TMAO) levels, the cross-sectional area of LV cardiomyocytes, and the area of LV interstitial fibrosis. Decreased the expression of ANP, BNP, β-MHC, collagen Iα, collagen III and CTGF. Inhibited TNF-α, IL-6, IL-1β, p65, TGF-β and Smad3 expression.

Animal Model:	Male and female ICR mice (8-weeks old)^[2].
Dosage:	0.2% and 1.0% DMB soluble in water.
Administration:	Oral gavage; 21 d.
Result:	Showed insignificantly effect on body weight, water intake, food intake, sexual preference, anxiety, depression and memory formation. Weakened the social dominance of mice.

Animal Model:	Pregnant Sprague-Dawley rats^[3].
Dosage:	1.0% DMB soluble in water.
Administration:	Oral gavage; gestation period and suckling period.
Result:	Increased kidney weight, plasma trimethylamine (TMA) level and acetic acid, reduced diastolic. Had significantly effect on gut microbiota composition.

3,3-DIMETHYL-1-BUTANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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3,3-DIMETHYL-1-BUTANOL Suppliers

Americas 1 Canada 1 China 164 Europe 1 Germany 3 India 6 Japan 1 Switzerland 1 United Kingdom 6 United States 31 Global 215

J & K SCIENTIFIC LTD.

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View Lastest Price from 3,3-DIMETHYL-1-BUTANOL manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 3, 3-Dimethyl-1-Butanol 624-95-3
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-12-05

Hebei Chuanghai Biotechnology Co,.LTD

Product: 3, 3-Dimethyl-1-Butanol 624-95-3
Price: US $5.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-23

Henan Fengda Chemical Co., Ltd

Product: 3,3-DIMETHYL-1-BUTANOL 624-95-3
Price: US $10.00-3.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-26

624-95-3, 3,3-DIMETHYL-1-BUTANOLRelated Search:

G-STROPHANTHIN 1,1-Cyclohexanediacetic acid 3,3,3-Triphenylpropionic acid 3,5,5-TRIMETHYL-2-CYCLOHEXEN-1-OL Cyclopentane-1,1-diacetic acid 3,3-Dimethylglutaric acid 3,3,5,5-TETRAMETHYLCYCLOHEXANOL Hyodeoxycholic acid 1-ETHYL-1-METHYLSUCCINIC ACID Estriol 3,3-Dimethylbutyric acid Ethyl chrysanthemumate 5-ALPHA-PREGNAN-3-ALPHA, 20-ALPHA-DIOL D-(+)-Camphoric acid 2,2-Dimethylsuccinic acid 11ALPHA-HYDROXYPROGESTERONE Prednisolone L(-)-Borneol

3,3-DIMETHYL-1-BUTANOL, 98%3,3-DIMETHYL-1-BUTANOL, 98%3,3-DIMETHYL-1-BUTANOL, 98%

Dimethylbutanol

3,3-Dimethylbutanol

3,3-Dimethylbutane-1-ol

3,3-dimethyl-1-butano

3,3-dimethyl-butan-1-ol

3,3-dimethylbutan-1-ol

3,3-DIMETHYL-1-BUTANOL

3,3-Dimethylbutylalcohol

NEOHEXANOL

3,3-Dimethyl-1-butanol &gt

1-Butanol, 3,3-dimethyl-

Neotame Impurity 2

3,3-Dimethyl-1-butanol, ≥ 95.0%

Neohexanol|||DMB|||DMB

624-95-3

CH33CCH2CH2OH

624953

ALCOHOL

C2 to C6

Oxygen Compounds

Organic Building Blocks

Building Blocks

Alcohols

C2 to C6

Oxygen Compounds