5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY
- Product Name
- 5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY
- CAS No.
- 681281-88-9
- Chemical Name
- 5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY
- Synonyms
- 5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY;Akt Inhibitor IV - CAS 681281-88-9 - Calbiochem;6-(2-Benzothiazolyl)-1-ethyl-2-[2-(methylphenylamino)ethenyl]-3-phenyl-1H-benzimidazolium iodide;6-benzothiazol-2-yl-1-ethyl-2-[2-(methyl-phenyl-amino)-vinyl]-3-phenyl-3H-benzoimidazol-1-ium iodide;5-(Benzo[d]thiazol-2-yl)-3-ethyl-2-(2-(methyl(phenyl)amino)vinyl)-1-phenyl-1H-benzo[d]imidazol-3-ium iodide;(E)-5-(benzo[d]thiazol-2-yl)-3-ethyl-2-(2-(methyl(phenyl)amino)vinyl)-1-phenyl-1H-benzo[d]imidazol-3-ium iodide
- CBNumber
- CB5497911
- Molecular Formula
- C31H27N4S.I
- Formula Weight
- 614.548
- MOL File
- 681281-88-9.mol
5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY Property
- storage temp.
- 2-8°C
- solubility
- DMSO: ≥10 mg/mL
- form
- solid
- color
- orange
- InChIKey
- NAYRELMNTQSBIN-UHFFFAOYSA-M
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- 124011
- Product name
- Akt Inhibitor IV
- Packaging
- 1mg
- Price
- $172
- Updated
- 2024/03/01
- Product number
- 124011
- Product name
- Akt Inhibitor IV
- Packaging
- 5mg
- Price
- $619
- Updated
- 2024/03/01
- Product number
- 15569
- Product name
- Akt Inhibitor IV
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $40
- Updated
- 2024/03/01
- Product number
- 15569
- Product name
- Akt Inhibitor IV
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $177
- Updated
- 2024/03/01
- Product number
- B2311
- Product name
- 5-(2-Benzothiazolyl)-3-ethyl-2-[2-(methylphenylamino)ethenyl]-1-phenyl-1H-benzimidazolium iodide
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $205
- Updated
- 2024/03/01
5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY Chemical Properties,Usage,Production
Uses
Akt Inhibitor IV is an Inhibitor of Akt protein kinase
Biological Activity
akt inhibitor iv is an inhibitor of akt activation that inhibits akt-mediated nuclear export of forkhead box class o transcription factor 1a (foxo1a; ic50 = 625 nm) and reduces phosphorylation of akt at ser473 and thr308 in a dose-dependent manner. akt inhibitor iv inhibits replication of parainfluenza virus 5 (piv5) in hela cells (ic50 = 520 nm). it also reduces the growth of cancer cells (ic50 = 0.3 μm for both jurkat and hela cells) via a reduction in mitochondrial polarization and increased production of reactive oxygen species (ros).
5-(2-BENZOTHIAZOLYL)-3-ETHYL-2-(-(METHY Preparation Products And Raw materials
Raw materials
Preparation Products
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