Description Supplements Mechanism of Action Shipping & Storage Condition
ChemicalBook > CAS DataBase List > 5-Methyltetrahydrofolic acid

5-Methyltetrahydrofolic acid

Description Supplements Mechanism of Action Shipping & Storage Condition
Product Name
5-Methyltetrahydrofolic acid
CAS No.
134-35-0
Chemical Name
5-Methyltetrahydrofolic acid
Synonyms
MethylFolate;5-methyltetrahydrofolate;methyl-THF;5-METHYL-THF;5-Methyl-5,6,7,8-tetrahydrofolic acid;5-Methyltetrahydrofolic Acid CalciuM Salt Trihydrate;Prefolic A;methyl-H4F;n5-CH3-THF;methyl acid
CBNumber
CB5500949
Molecular Formula
C20H25N7O6
Formula Weight
459.46
MOL File
134-35-0.mol
More
Less

5-Methyltetrahydrofolic acid Property

Melting point:
>300°C (dec.)
Density 
1.62±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Aqueous Base (Slightly, Sonicated)
form 
Solid
pka
3.51±0.10(Predicted)
color 
Pale Beige
Stability:
Hygroscopic
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
16159
Product name
5-Methyltetrahydrofolic Acid
Purity
≥98%
Packaging
5mg
Price
$158
Updated
2021/12/16
Cayman Chemical
Product number
16159
Product name
5-Methyltetrahydrofolic Acid
Purity
≥98%
Packaging
1mg
Price
$35
Updated
2021/12/16
Cayman Chemical
Product number
16159
Product name
5-Methyltetrahydrofolic Acid
Purity
≥98%
Packaging
10mg
Price
$263
Updated
2021/12/16
Usbiological
Product number
017430
Product name
5-Methyltetrahydrofolic Acid Calcium Salt Trihydrate
Packaging
10mg
Price
$446
Updated
2021/12/16
TRC
Product number
M338145
Product name
N-MethyltetrahydrofolicAcid
Packaging
1g
Price
$85
Updated
2021/12/16
More
Less

5-Methyltetrahydrofolic acid Chemical Properties,Usage,Production

Description

5-Methyltetrahydrofolic acid (5-MTHF) is an active folate metabolite. It plays an important role in the synthesis of methionine from homocysteine by donating methyl group. 5-Methyltetrahydrofolic acid-(glutamic acid-13C5) is an isotope of vitamin B9 wherein all the five glutamate carbons are replaced by 13C6 carbon.

Supplements

5-Methyltetrahydrofolic acid is a biologically active form of folic acid. 5-Methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. 5-Methyltetrahydrofolic acid is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid.

Mechanism of Action

Prefolic A, also known as 5-Methyltetrahydrofolate, is a biologically active form of folic acid that functions, in conjunction with vitamin B12, as a methyl-group donor involved in the conversion of homocysteine to methionine. Methyl folate is an active metabolite of folic acid. Vitamin supplement in health care products.

Shipping & Storage Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. Stored in dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Shelf Life can be more than 2 years if stored properly.

Chemical Properties

Off-White Solid

Uses

5-Methyltetrahydrofolic acid-(glutamic acid-13C5) can be used as a stable isotope internal standard for accurate data interpretation in citrus juice samples by LC-MS.

Uses

5-Methyltetrahydrofolic acid is a metabolite of Folic acid; inhibits photosensitization reactions and strand breaks in DNA. 5-Methyltetrahydrofolic acid-(glutamic acid-13C5) can be used as a stable isotope internal standard for accurate data interpretation in citrus juice samples by LC-MS.

General Description

5-Methyltetrahydrofolic acid (5-MTHF) is an active folate metabolite. It plays an important role in the synthesis of methionine from homocysteine by donating methyl group.
5-Methyltetrahydrofolic acid-(glutamic acid-13C5) is an isotope of vitamin B9 wherein all the five glutamate carbons are replaced by 13C6 carbon.

5-Methyltetrahydrofolic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-Methyltetrahydrofolic acid Suppliers

Canada 2 China 122 France 1 Germany 1 India 10 Switzerland 1 United States 10 USA 1 Global 148
Shaanxi Pioneer Biotech Co.,Ltd
Tel
029-029-84385017-8001-8001 18220517932
Fax
QQ3340501466
Email
sales5@pioneerbiotech.com
Country
China
ProdList
474
Advantage
58
Manhag Testing Technology Co., Ltd
Tel
020-020-3846236 17688849268
Email
2443244976@qq.com
Country
China
ProdList
7775
Advantage
58
Tongchuan Boliante Chemical Co. LTD
Tel
17719597442
Email
642232259@qq.com
Country
China
ProdList
92
Advantage
58
SU ZHOU EVOL BIO-TECH CO.,LTD
Tel
15706135552
Email
sales@evol-biotech.com
Country
China
ProdList
20
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9648
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
11481
Advantage
59
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Shanghai Synchem Pharma Co., ltd
Tel
21-619849051-1 18521059765
Email
synchempharma@aliyun.com
Country
China
ProdList
6463
Advantage
55
Artis Biotech Co. Ltd.
Tel
0575-18780151478 18582380095
Fax
0575-89298961
Email
sales@artisbio.com
Country
China
ProdList
2964
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9923
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Wuhan Netcom Electronic Commerce Limited
Tel
18064670521
Fax
0757-88210752
Email
2355935187@ycphar.com
Country
China
ProdList
4879
Advantage
58
Xi'an boliante Chemical Co., Ltd.
Tel
17719597442
Fax
-
Email
642232259@qq.com
Country
China
ProdList
449
Advantage
58
Aikon International Limited
Tel
025-66113011 18112977050
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
16027
Advantage
58
Shaanxi Pioneer Biotech Co., Ltd.
Tel
029-029-86629612 18202932191
Email
sales3@pioneerbiotech.com
Country
China
ProdList
336
Advantage
55
Nanjing Daqin Pharmaceutical Technology Co., Ltd.
Tel
025-58470199 18351831988
Fax
025-58470199
Email
sales@daqinpharma.com
Country
China
ProdList
312
Advantage
58
Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.
Tel
027-51831887 15337167856
Fax
027-51837635 QQ1165326703
Email
hubeixinyuanshun@163.com
Country
China
ProdList
10295
Advantage
58
Nanjing crow LuNing pharmaceutical technology co., LTD
Tel
13382066392
Country
CHINA
ProdList
4877
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2815688 13927872512
Fax
0751-8963795
Email
3007421951@qq.com
Country
China
ProdList
10057
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57412
Advantage
58
Finetech Industry Limited
Tel
+86-27-87465837 +8618971612321
Fax
86 27 87772287
Email
info@finetechnology-ind.com
Country
China
ProdList
9639
Advantage
58
Hebei Mojin Biotechnology Co., Ltd
Tel
+86 13288715578 +8613288715578
Email
sales@hbmojin.com
Country
China
ProdList
12839
Advantage
58
Shandong Zhishang New Material Co., Ltd.
Tel
+8617653113209
Email
sales002@sdzschem.com
Country
China
ProdList
3049
Advantage
58
Guangzhou TongYi biochemistry technology Co.,LTD
Tel
+8613073028829
Email
mack@tongyon.com
Country
China
ProdList
2994
Advantage
58
Hubei Ipure Biology Co., Ltd
Tel
+8613367258412
Fax
18062427325
Email
ada@ipurechemical.com
Country
China
ProdList
10319
Advantage
58
Zhuoer Chemical Co., Ltd
Tel
02120970332; +8613524231522
Fax
+86-21-58816016
Email
sales@zhuoerchem.com
Country
China
ProdList
2904
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52849
Advantage
58
AFINE CHEMICALS LIMITED
Tel
+86-0571-85134551
Fax
008657185134895
Email
sales@afinechem.com
Country
China
ProdList
15354
Advantage
58
HONG KONG IPURE BIOLOGY CO.,LIMITED
Tel
86 18062405514 18062405514
Email
ada@ipurechemical.com
Country
CHINA
ProdList
3461
Advantage
58
Hubei Xingcheng Biotechnology Co., Ltd
Tel
19171210221
Fax
QQ:3505191060
Email
3371991952@qq.com
Country
China
ProdList
958
Advantage
58
Hebei Weibang Biotechnology Co., Ltd
Tel
+8615531157085
Fax
whatapp+8619930503282
Email
abby@weibangbio.com
Country
China
ProdList
8811
Advantage
58
Guangdong Wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2886766 13927870850
Fax
0751-2886756
Email
3001267247@qq.com
Country
China
ProdList
9974
Advantage
58
Shaanxi Pioneer Biotech Co., Ltd .
Tel
+8613259417953
Fax
029-84385017
Email
sales@pioneerbiotech.com
Country
China
ProdList
3000
Advantage
58
Shandong chuangyingchemical Co., Ltd.
Tel
18853181302
Email
sale@chuangyingchem.com
Country
CHINA
ProdList
5906
Advantage
58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49312
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29811
Advantage
58
Wuhan lanabai Pharmaceutical Chemical Co., Ltd
Tel
15307151931
Fax
QQ-2355680
Email
2355680@qq.com
Country
China
ProdList
5547
Advantage
58
Beijing Aomi Jiade Pharmaceutical Technology Co., Ltd
Tel
+86-13522808617 +86-13522808617
Email
omichem@126.com
Country
China
ProdList
9211
Advantage
58
Xi 'an Xinlu Biological Technology Co. LTD
Tel
13259841664
Email
xaxlbio@vip.163.com
Country
China
ProdList
510
Advantage
58
Wuhan plov Biotechnology Co., Ltd
Tel
17612776928
Fax
17612776928
Email
17612776928@qq.com
Country
China
ProdList
4971
Advantage
58
Shaanxi Pioneer Biotech Co.,Ltd
Tel
18629309720 18629309720
Email
sales@pioneerbiotech.com
Country
China
ProdList
328
Advantage
58
Hubei Longxin Chemical Industry Co., Ltd.
Tel
15271551270
Email
ycwlb056@yeah.net
Country
China
ProdList
2086
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 13675144456
Fax
025-85563444
Email
sean.lv@synzest.com
Country
China
ProdList
11438
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44808
Advantage
58
More
Less

View Lastest Price from 5-Methyltetrahydrofolic acid manufacturers

airuikechemical co., ltd.
Product
methyl folate 134-35-0
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-08
Hebei Kingfiner Technology Development Co.Ltd
Product
5-Methyltetrahydrofolic acid 134-35-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
50000kg
Release date
2024-06-17
Hebei Weibang Biotechnology Co., Ltd
Product
5-Methyltetrahydrofolic acid 134-35-0
Price
US $10.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2021-09-28

134-35-0, 5-Methyltetrahydrofolic acidRelated Search:

Folic acid Lipoic acid L-Tetrahydrofolic Acid 2-Methyltetrahydrofuran Whey protein concentrate 2-Methylnaphthalene Hydrogen Imidazolidine ANTIOXIDANT 765 (2S)-2-[[4-[Bis[(2-aMino-4-oxo-1,4-dihydropteridin-6-yl)Methyl]aMino]benzoyl]aMino]pentanedioic Acid Folic Acid Impurity C N-(p-Aminobenzoyl)glutamic acid 6-hydroxymethylpterin Levomefolate calcium 2-Amino-7-(chloromethyl)pteridin-4(1H)-one Folitixorin (Mixture of DiastereoMers) 2-Amino-4-hydroxy-1H-pteridine N-(4-aminobenzoyl)- D-Glutamic acid

  • methyl acid
  • 5-Methyl-5,6,7,8-tetrahydrofolic acid
  • 5-Methyltetrahydropteroyl monoglutamate
  • 5-Methyltetrahydropteroylglutamic acid
  • N5-Methyltetrahydropteroylglutamate
  • N-Methyltetrahydrofolate
  • N-Methyltetrahydrofolic acid
  • Prefolic A
  • L-Methyl Folate
  • (2S)-2-(4-(((2-Amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid
  • 5-Methyltetrahydrofolate (mixture of diastereomers)
  • 5-methyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
  • 5-METHYL-THF
  • methyl-H4F
  • methyl-THF
  • n5-methyltetrahydrofolate
  • N5-methyltetrahydropteroyl mono-L-glutamate
  • N5-methyl-THF
  • 5-Methyltetrahydrofolic Acid Calcium Salt Trihydrate (Mixture of Diastereomers)
  • 5-Methyltetrahydrofolic Acid CalciuM Salt Trihydrate
  • 5-Methyltetrahydrofolic Acid Calcium Salt Trihydrate (Also See: L375720)
  • N-[4-[[(2-AMino-3,4,5,6,7,8-hexahydro-5-Methyl-4-oxo-6-pteridinyl)Methyl]aMino]benzoyl]-L-glutaMic Acid CalciuM Trihydrate
  • N5-Methyl tetrahydrofolic acid
  • METHYL FOLATE(METAFOLIN)(P)
  • MethylFolate
  • 2-[4-[(2-amino-5-methyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]aminopentanedioic acid
  • n5-CH3-THF
  • 5-methyltetrahydrofolate
  • METHYLTETRAHYDROFOLICACID
  • 5-methyl-5,6,7,8-tetrahydrofolate
  • N-[4-[[(2-Amino-1,4-dihydro-4-oxopteridin)-6-ylmethyl]amino]benzoyl]-L-glutamic acid 5-methyl ester
  • L-Glutamic acid, N-[4-[[(2-amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-
  • Folic Acid Impurity 36
  • 5-Methyltetrahydrofolic acid-(glutamic acid-13C5) 99 atom % 13C, 95% (CP)
  • 5-Methyltetrahydrofolic acid-(glutamic acid-13C5)
  • 5-methyltetrahydrofolicaci
  • 5-Methyltetrahydrofolic acid 1mg/ml in water
  • 5-METHYLTETRAHYDROFOLIC ACID
  • L-methylfolate Methyl Folate
  • 5-Methylterahydrofolic acid
  • 5-Methyltetrahydrofolic acid in DMSO:H2O=1:1
  • 134-35-0
  • C20H29CaN7O9
  • C20H20N7O6
  • Bases & Related Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Nucleotides
  • Pharmaceuticals