ChemicalBook > CAS DataBase List > 3 5-DIFLUOROSALICYLALDEHYDE 97

3 5-DIFLUOROSALICYLALDEHYDE 97

Product Name: 3 5-DIFLUOROSALICYLALDEHYDE 97
CAS No.: 63954-77-8
Chemical Name: 3 5-DIFLUOROSALICYLALDEHYDE 97
Synonyms: 3,5-Difluoro-2-hydrox;3,5-Difluorosalicaldehyde;3 5-Difluorosalicyaldehyde;3,5-Difluorosalicylaldehyde 97%;3 5-DIFLUOROSALICYLALDEHYDE 97;3,5-difluoro-2-hydroxybenzaldehde;Benzaldehyde, 3,5-difluoro-2-hydroxy-;3,5-Difluoro-2-hydroxybenzaldehyde98%;3,5-Difluoro-2-hydroxybenzaldehyde 98%;3,5-Difluorosalicylaldehyde, 2,4-Difluoro-6-formylphenol
CBNumber: CB5504260
Molecular Formula: C7H4F2O2
Formula Weight: 158.1
MOL File: 63954-77-8.mol

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3 5-DIFLUOROSALICYLALDEHYDE 97 Property

Melting point:: 87-91 °C (lit.)
Boiling point:: 181.9±35.0 °C(Predicted)
Density: 1.464±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: solid
pka: 6.94±0.23(Predicted)
color: White to off-white
InChI: InChI=1S/C7H4F2O2/c8-5-1-4(3-10)7(11)6(9)2-5/h1-3,11H
InChIKey: QGSAZWCEHUYVMW-UHFFFAOYSA-N
SMILES: C(=O)C1=CC(F)=CC(F)=C1O

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 2912490090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: D445913
Product name: 3,5-Difluoro-2-hydroxybenzaldehyde
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: PC1112
Product name: 3,5-Difluoro-2-hydroxybenzaldehyde
Purity: 98%
Packaging: 1g
Price: $73
Updated: 2021/12/16

AK Scientific

Product number: 9799AB
Product name: 3,5-Difluoro-2-hydroxybenzaldehyde
Packaging: 1g
Price: $79
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2615-3-31
Product name: 3,5-Difluoro-2-hydroxybenzaldehyde
Purity: 98%
Packaging: 1g
Price: $80
Updated: 2021/12/16

Apolloscientific

Product number: PC1112
Product name: 3,5-Difluoro-2-hydroxybenzaldehyde
Purity: 98%
Packaging: 5g
Price: $247
Updated: 2021/12/16

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3 5-DIFLUOROSALICYLALDEHYDE 97 Chemical Properties,Usage,Production

Uses

3,5-Difluorosalicylaldehyde may be used in the synthesis of Ni[CpFe(η⁵-C₅H₄)-C(O)CH=C(CH₃)N-o-C₆H₄N=CH-(2-O,3,5-F₂-C₆H₂)] (Cp = cyclopentyl) and Zn(salphenazine) complex.

General Description

3,5-Difluorosalicylaldehyde has been synthesized by employing 2,4-difluorophenol as a starting reagent.

Synthesis

367-27-1

68-12-2

63954-77-8

Phosphoryl chloride (12 g, 77 mmol) was slowly added dropwise to anhydrous N,N-dimethylformamide (8.4 g, 0.12 mol) at 0 °C and under nitrogen protection while maintaining stirring. After the dropwise addition, the reaction mixture was continued to be stirred at this temperature for 30 min. Subsequently, a solution of N,N-dimethylformamide (50 mL) of 2,4-difluorophenol (5.0 g, 39 mmol) was slowly added dropwise to the above mixture. After completion of the dropwise addition, the reaction mixture was transferred to room temperature conditions with continuous stirring for 5 hours. Upon completion of the reaction, the reaction was carefully quenched with water and extracted with ethyl acetate (3 x 150 mL). The organic phases were combined, washed sequentially with water and saturated brine, dried over anhydrous sodium sulfate, and finally concentrated under reduced pressure to afford the target product 3,5-difluoro-2-hydroxybenzaldehyde (5.5 g, 90% yield) as a yellow oil.

References

[1] Patent: WO2015/66371, 2015, A1. Location in patent: Paragraph 00326-00327

3 5-DIFLUOROSALICYLALDEHYDE 97 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3 5-DIFLUOROSALICYLALDEHYDE 97 manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 3,5-Difluorosalicylaldehyde 63954-77-8
Price: US $0.10-10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200TONS
Release date: 2025-08-18

Career Henan Chemical Co

Product: 3 5-DIFLUOROSALICYLALDEHYDE 97 63954-77-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg,5kg,100kg
Release date: 2019-07-04

63954-77-8, 3 5-DIFLUOROSALICYLALDEHYDE 97Related Search:

3,5-DIFLUORO-2-METHOXYBENZALDEHYDE 3',5'-DIFLUORO-2'-HYDROXYACETOPHENONE 3,5-DIFLUORO-2-METHOXYBENZOIC ACID 5,7-DIFLUORO-BENZOFURAN-3-ONE 3,5-DIFLUORO-2-METHOXYBENZAMIDE 3,5-DIFLUORO-2-METHOXYBENZOYL CHLORIDE 2-ETHOXY-3,5-DIFLUOROBENZOIC ACID 2-ETHOXY-3,5-DIFLUOROBENZALDEHYDE 3,4,5,6-TETRAFLUORO-2-HYDROXYBENZOIC ACID 2-ETHOXY-3,5-DIFLUOROBENZOYL CHLORIDE 3 5-DIFLUOROSALICYLALDEHYDE 97 3,5-DIFLUORO-2-HYDROXY-BENZOIC ACID 2-ETHOXY-3,5-DIFLUOROBENZAMIDE BUTTPARK 35\07-35 methyl 3,5-difluoro-2-methoxybenzoate RARECHEM AL BI 1422 5,6,7,8-TETRAFLUORO-2-METHYL-4-OXO-4H-CHROMENE-3-CARBOXYLIC ACID ETHYL ESTER 3,5-DIFLUORO-2-HYDROXY-BENZOIC ACID METHYL ESTER

3,5-Difluoro-2-hydrox

3 5-DIFLUOROSALICYLALDEHYDE 97

3,5-Difluoro-2-hydroxybenzaldehyde 98%

3,5-difluoro-2-hydroxybenzaldehde

3,5-Difluorosalicaldehyde

3,5-Difluorosalicylaldehyde, 2,4-Difluoro-6-formylphenol

3,5-Difluorosalicylaldehyde 97%

3,5-Difluoro-2-hydroxybenzaldehyde98%

Benzaldehyde, 3,5-difluoro-2-hydroxy-

3 5-Difluorosalicyaldehyde

63954-77-8

F2C6H2OHCHO

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