2-HYDROXYCYCLOHEXANONE DIMER Property

Melting point:

100-107 °C(lit.)

Boiling point:

83-86 °C13 mm Hg(lit.)

Flash point:

175 °F

storage temp. 

2-8°C

form 

Powder

color 

Off-white

Water Solubility 

Partly miscible in water.

Safety

Hazard Codes 

F,Xi

Risk Statements 

11-36/37/38

Safety Statements 

16-26-36

RIDADR 

UN 1325 4.1/PG 3

WGK Germany 

3

F 

9-21

HazardClass 

4.1

PackingGroup 

III

HS Code 

29144090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H228Flammable solid

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

2-HYDROXYCYCLOHEXANONE DIMER Chemical Properties,Usage,Production

Chemical Properties

Off-white powder

Uses

Reactant involved in:• ;Synthesis of substrated for tin tetrachloride mediated fragmentation to produce ynones and ynoates1• ;Tandem oxidation coupling reactions with diamines2• ;Asymmetric allylic alkylation of enolates3• ;Formate reduction of allylic carbonates for polypropionate systems4

Uses

It is a reactant involved in the synthesis of substrates for tin tetrachloride mediated fragmentation to produce ynones and ynoates, tandem oxidation coupling reactions with diamines, asymmetric allylic alkylation of enolates and formate reduction of allylic carbonates for polypropionate systems.

Uses

Reactant involved in:

• Synthesis of substrated for tin tetrachloride mediated fragmentation to produce ynones and ynoates
• Tandem oxidation coupling reactions with diamines
• Asymmetric allylic alkylation of enolates
• Formate reduction of allylic carbonates for polypropionate systems

Definition

ChEBI: 2-hydroxycyclohexan-1-one is a secondary alpha-hydroxy ketone and a hydroxycyclohexanone.

Synthesis Reference(s)

The Journal of Organic Chemistry, 51, p. 130, 1986 DOI: 10.1021/jo00352a002
Synthetic Communications, 25, p. 3141, 1995 DOI: 10.1080/00397919508015463
Tetrahedron Letters, 36, p. 3031, 1995 DOI: 10.1016/0040-4039(95)00419-D