ChemicalBook > CAS DataBase List > METHYL 2-AMINO-6-FLUOROBENZOATE

METHYL 2-AMINO-6-FLUOROBENZOATE

Product Name
METHYL 2-AMINO-6-FLUOROBENZOATE
CAS No.
86505-94-4
Chemical Name
METHYL 2-AMINO-6-FLUOROBENZOATE
Synonyms
Methyl 2-amino-6-fluorobenzaote;METHYL 2-AMINO-6-FLUOROBENZOATE;Benzoic acid, 2-aMino-6-fluoro-, Methyl ester
CBNumber
CB5511565
Molecular Formula
C8H8FNO2
Formula Weight
169.15
MOL File
86505-94-4.mol
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METHYL 2-AMINO-6-FLUOROBENZOATE Property

Boiling point:
266.6±25.0 °C(Predicted)
Density 
1.264±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
1.18±0.10(Predicted)
Appearance
Off-white to light yellow Solid
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Safety

HS Code 
2916310090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M288480
Product name
methyl2-amino-6-fluorobenzoate
Packaging
100mg
Price
$90
Updated
2021/12/16
ChemScene
Product number
CS-0045066
Product name
Methyl2-amino-6-fluorobenzoate
Purity
99.07%
Packaging
250mg
Price
$18
Updated
2021/12/16
AK Scientific
Product number
J96474
Product name
Methyl2-amino-6-fluorobenzoate
Packaging
100mg
Price
$40
Updated
2021/12/16
AK Scientific
Product number
Z1757
Product name
Methyl2-amino-6-fluorobenzoate
Packaging
100mg
Price
$52
Updated
2021/12/16
AK Scientific
Product number
J96474
Product name
Methyl2-amino-6-fluorobenzoate
Packaging
250mg
Price
$80
Updated
2021/12/16
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METHYL 2-AMINO-6-FLUOROBENZOATE Chemical Properties,Usage,Production

Synthesis

434-76-4

18107-18-1

86505-94-4

Example 134 (±)-5-[Acetyl-(3,5-bis(trifluoromethyl)benzyl)amino]-6-fluoro-tetrahydrobenzo[b]azepine-1-carboxylic acid Synthesis Procedure 1. Methyl 2-amino-6-fluorobenzoate Preparation: 2-amino-6-fluorobenzoic acid (3.00 g, 19.3 mmol) was dissolved in a ethyl acetate (59 mL) and ethanol (59 mL) (59 mL) and ethanol (59 mL) in a mixed solvent. Trimethylsilylated diazomethane (19.3 mL, 38.68 mmol, 2M in hexane) was slowly added to this solution and the reaction mixture was stirred at room temperature for 1.5 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure to afford methyl 2-amino-6-fluorobenzoate (3.26 g, quantitative yield). Mass spectrum (electrospray positive ion mode): m/z 170 [M+H]+.

References

[1] Patent: WO2005/37796, 2005, A1. Location in patent: Page/Page column 131

METHYL 2-AMINO-6-FLUOROBENZOATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL 2-AMINO-6-FLUOROBENZOATE Suppliers

Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80