GW284543

Product Name: GW284543
CAS No.: 790186-68-4
Chemical Name: GW284543
Synonyms: GW284543;UNC10225170;GW284543 HCl;GW284543 (UNC10225170);GW284543, 10 mM in DMSO;6,7-Dimethoxy-N-(3-phenoxyphenyl)quinolin-4-amine;4-Quinolinamine, 6,7-dimethoxy-N-(3-phenoxyphenyl)-;Inhibitor,inhibit,GW 284543,GW284543,UNC 10225170,MIA PaCa-2,GW-284543,Mitogen-activated protein kinase kinase,MEK,MAPKK,UNC-10225170,MAP2K
CBNumber: CB55419749
Molecular Formula: C23H20N2O3
Formula Weight: 372.42
MOL File: 790186-68-4.mol

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GW284543 Property

storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMSO:67.0(Max Conc. mg/mL);179.9(Max Conc. mM)
form: Solid
color: Off-white to gray

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0078813
Product name: GW284543
Purity: 99.86%
Packaging: 5mg
Price: $90
Updated: 2021/12/16

ChemScene

Product number: CS-0078813
Product name: GW284543
Purity: 99.86%
Packaging: 10mg
Price: $140
Updated: 2021/12/16

ChemScene

Product number: CS-0078813
Product name: GW284543
Purity: 99.86%
Packaging: 50mg
Price: $450
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: KIN0008623
Product name: GW-284543
Purity: 95.00%
Packaging: 5MG
Price: $457.32
Updated: 2021/12/16

ChemScene

Product number: CS-0078813
Product name: GW284543
Purity: 99.86%
Packaging: 100mg
Price: $750
Updated: 2021/12/16

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GW284543 Chemical Properties,Usage,Production

Uses

GW284543 (UNC10225170) is a selective MEK5 inhibitor. GW284543 reduces pERK5, and decreases endogenous MYC protein[1].

IC 50

MEK5

References

[1] Vaseva AV, et al. KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism. Cancer Cell. 2018 Nov 12;34(5):807-822.e7. DOI:10.1016/j.ccell.2018.10.001

GW284543 Preparation Products And Raw materials

Raw materials

Preparation Products

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GW284543 Suppliers

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790186-68-4, GW284543Related Search:

GW 284543 hydrochloride - UNC 10225170 hydrochloride 5-[3-Methoxy-4-(4-methoxy-benzyloxy)-benzyl]-pyrimidine-2,4-diamine GW9508 2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]- GW788388 GW9662 GW441756 GW5074

GW284543

GW284543 (UNC10225170)

UNC10225170

4-Quinolinamine, 6,7-dimethoxy-N-(3-phenoxyphenyl)-

6,7-Dimethoxy-N-(3-phenoxyphenyl)quinolin-4-amine

Inhibitor,inhibit,GW 284543,GW284543,UNC 10225170,MIA PaCa-2,GW-284543,Mitogen-activated protein kinase kinase,MEK,MAPKK,UNC-10225170,MAP2K

GW284543 HCl

GW284543, 10 mM in DMSO

790186-68-4