E2F1 antibody
Source Reactivity Background References- Product Name
- E2F1 antibody
- Chemical Name
- E2F1 antibody
- Synonyms
- E2F1 antibody;Mouse Monoclonal E2F1 Antibody
- CBNumber
- CB55623900
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb378736
- Product name
- E2F1 antibody
- Purity
- Tissue culture supernatant
- Packaging
- 100μL
- Price
- $399.5
- Updated
- 2021/12/16
- Product number
- orb500525
- Product name
- E2F1 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $421.6
- Updated
- 2021/12/16
- Product number
- orb10568
- Product name
- E2F1 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $421.6
- Updated
- 2021/12/16
- Product number
- orb500525
- Product name
- E2F1 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 200μg
- Price
- $673.2
- Updated
- 2021/12/16
- Product number
- orb10568
- Product name
- E2F1 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 200μg
- Price
- $673.2
- Updated
- 2021/12/16
E2F1 antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human
Background
The E2F transcription factors are essential for regulation of the cell cycle. Physiological E2F is a heterodimer composed of an E2F subunit together with a DP subunit. Six members of the E2F family have been identified, and each E2F subunit has a DNA binding and a dimerization domain. E2F-1 to -5 activate transcription. E2F-1 to -3 bind pRb, and E2F-4 and -5 bind p107 or p130, and these interactions are under cell cycle control. E2F-1 has oncogenic properties in vivo and in vitro. E2F-1 can induce apoptosis through p53-dependent and -independent mechanisms. E2F-1 is stress-responsive, and is regulated by a PI3-kinase-like kinase family such as the ATM/ATR kinases.
References
[1] Helin, K. (1998) Curr. Opin. Genet. Dev. 8, 28-35.
[2] Dyson, N. (1998) Genes Dev. 12, 2245-2262.
[3] Helin, K. et al. (1993) Genes Dev. 7, 1850-1861.
[4] Wu, C. et al. (1995) Mol. Cell. Biol. 15, 2536-2546.
[5] Takahashi, Y. et al. (2000) Genes Dev. 14, 804-816.
[6] Wu, L. et al. (2001) Nature 414, 457-462.
[7] Gaubatz, S. et al. (2000) Mol. Cell 6, 729-735.
[8] Hurford, R. K. et al. (1997) Genes Dev. 11, 1447-1463.
[9] Tsai, K. Y. et al. (1998) Mol. Cell 2, 293-304.
[10] Garcia, I. et al. (2000) Cell Growth Differ. 11, 91-98.
E2F1 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
E2F1 antibody Suppliers
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