USP28 antibody
Source Reactivity Background References- Product Name
- USP28 antibody
- Chemical Name
- USP28 antibody
- Synonyms
- USP28 antibody
- CBNumber
- CB55703983
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb100097
- Product name
- USP28 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 5μg(Trial Size)
- Price
- $66.3
- Updated
- 2021/12/16
- Product number
- orb100097
- Product name
- USP28 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 20μg(Trial Size)
- Price
- $141.1
- Updated
- 2021/12/16
- Product number
- orb100097
- Product name
- USP28 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $421.6
- Updated
- 2021/12/16
- Product number
- orb100097
- Product name
- USP28 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 200μg
- Price
- $673.2
- Updated
- 2021/12/16
USP28 antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human;Mouse
Background
Ubiquitinating enzymes catalyze protein ubiquitination, a reversible process countered by deubiquitinating enzymes action. There are five DUB subfamilies including the USP, UCH, OTU, MJD and JAMM enzymes. USP28 is an important member of the USP subfamily. USP28 can bind to and deubiquinate several target proteins in DNA-damage pathway, resulting in their stability, including p53BP1 and Chk2. USP28 also plays an important role in Myc related signaling by binding through FBW7α to Myc . It catalyzes the deubiquitinylation of Myc, thereby promoting its stabilization and contributing to tumor-cell growth.
References
[1] Nijman, S.M. et al. (2005) Cell 123, 773-86.
[2] Nalepa, G. et al. (2006) Nat Rev Drug Discov 5, 596-613.
[3] Valero, R. et al. (2001) Genome Biol 2, RESEARCH0043.
[4] Zhang, D. et al. (2006) Cell 126, 529-42.
[5] Popov, N. et al. (2007) Nat Cell Biol 9, 765-74.
USP28 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
USP28 antibody Suppliers
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- 400821347
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- China
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- 027-87196173
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- China
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- Enzo Biochem Inc. 13797054060
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- 18886812933
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