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Tauro-α-muricholic acid sodium salt

Product Name
Tauro-α-muricholic acid sodium salt
CAS No.
2260905-08-4
Chemical Name
Tauro-α-muricholic acid sodium salt
Synonyms
Tauro-α-Muricholic Acid-[d5] Sodium Salt;2-[[(3α,5β,6β,7α)-3,6,7-trihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonicacid,monosodiumsalt
CBNumber
CB55985161
Molecular Formula
C26H46NNaO7S
Formula Weight
539.7
MOL File
2260905-08-4.mol
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Tauro-α-muricholic acid sodium salt Property

storage temp. 
Store at -20°C
solubility 
DMF: 10 mg/mL; DMSO: 10 mg/mL; DMSO:PBS(pH 7.2) (1:4): 0.2 mg/mL; Ethanol: 1 mg/mL
form 
A crystalline solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20288
Product name
Tauro-α-muricholic Acid (sodium salt)
Packaging
1mg
Price
$158
Updated
2024/03/01
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Tauro-α-muricholic acid sodium salt Chemical Properties,Usage,Production

Description

Tauro-α-muricholic acid (TαMCA) is an antagonist of the farnesoid X receptor (FXR; IC50 = 28 μM) and a taurine-conjugated form of the murine-specific primary bile acid α-muricholic acid .1 TαMCA is common in rodents but has also been found in small amounts in human serum.2

References

1. Sayin, S.I., Wahlstr?m, A., Felin, J., et al. Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist Cell Metab. 17(2),225-235(2013).
2. García-Ca?averas, J.C., Donato, M.T., Castell, J.V., et al. Targeted profiling of circulating and hepatic bile acids in human, mouse, and rat using a UPLC-MRM-MS-validated method J. Lipid Res. 53(10),2231-2241(2012).

Tauro-α-muricholic acid sodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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Tauro-α-muricholic acid sodium salt Suppliers

China 7 India 1 United States 2 Global 10
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16314854226
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info@bocsci.com
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United States
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Cayman Chemical Company
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cayman@caymanchem.com
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2260905-08-4, Tauro-α-muricholic acid sodium saltRelated Search:


  • 2-[[(3α,5β,6β,7α)-3,6,7-trihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonicacid,monosodiumsalt
  • Tauro-α-Muricholic Acid-[d5] Sodium Salt
  • 2260905-08-4