CHO-PEG8-azide

Product Name: CHO-PEG8-azide
CAS No.: 2353410-13-4
Chemical Name: CHO-PEG8-azide
Synonyms: CHO-PEG8-azide
CBNumber: CB56199514
Molecular Formula: C18H35N3O9
Formula Weight: 437.49
MOL File: 2353410-13-4.mol

More

Less

CHO-PEG8-azide Property

solubility: Soluble in Water, DMSO, DCM, DMF

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

BroadPharm

Product number: BP-24116
Product name: Ald-CH2-PEG8-azide
Purity: 98%
Packaging: 100mg
Price: $380
Updated: 2021/12/16

BroadPharm

Product number: BP-24116
Product name: Ald-CH2-PEG8-azide
Purity: 98%
Packaging: 250mg
Price: $750
Updated: 2021/12/16

BroadPharm

Product number: BP-24116
Product name: Ald-CH2-PEG8-azide
Purity: 98%
Packaging: 500mg
Price: $1120
Updated: 2021/12/16

More

Less

CHO-PEG8-azide Chemical Properties,Usage,Production

Description

Ald-CH2-PEG8-azide is a monodisperse PEG crosslinker containing an azide group and an aldehyde group. The azide group enables PEGylation via Click Chemistry. PEG8 spacer increases solubility in aqueous media. aldehyde can be used in PEGylation through its reaction with hydrazine or hydrazide forming a hydrolytic acyl hydrozone linkage.

Uses

Ald-CH2-PEG8-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Ald-CH2-PEG8-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

CHO-PEG8-azide Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

CHO-PEG8-azide Suppliers

China 7 United States 3 Global 10

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-0431-80514535 19917294565
Email: et@chemextension.com
Country: China
ProdList: 3935
Advantage: 55

Alfa Chemistry

Tel: +1-5166625404;
Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
Country: United States
ProdList: 20405
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Zhengzhou Akem Chemical Co., Ltd

Tel: 13303867194
Email: 3001317055@qq.com
Country: China
ProdList: 9679
Advantage: 58

Shanghai Easy CDMO Co.,Ltd

Tel: 021-61734564 13854185395;
Email: info@easycdmo.com
Country: China
ProdList: 10024
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29257
Advantage: 58

Henan Mengtai Pharmaceutical Technology Co., Ltd

Tel: 176345344 7 17634854698
Email: 1959525201@qq.com
Country: China
ProdList: 10000
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 52923
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: +undefined18143011203
Email: info@chemextension.com
Country: China
ProdList: 42056
Advantage: 58

2353410-13-4, CHO-PEG8-azideRelated Search:

Azide-PEG3-aldehyde Ald-PEG5-Azide Ald-PEG3-Azide

CHO-PEG8-azide

2353410-13-4