Ald-PEG3-Azide
- Product Name
- Ald-PEG3-Azide
- CAS No.
- 1002342-83-7
- Chemical Name
- Ald-PEG3-Azide
- Synonyms
- Ald-PEG3-Azide;N3-PEG3-CH2CHO;CHO-PEG3-azide;Ald-CH2-PEG3-N3;ALD-CH2-PEG3-AZIDE
- CBNumber
- CB93062297
- Molecular Formula
- C8H15N3O4
- Formula Weight
- 217.23
- MOL File
- 1002342-83-7.mol
Ald-PEG3-Azide Property
- solubility
- Soluble in Water, DMSO, DMF, DCM
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A576133
- Product name
- Ald-PEG3-azide
- Packaging
- 10mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- BP-21715
- Product name
- Ald-CH2-PEG3-azide
- Purity
- 98%
- Packaging
- 100mg
- Price
- $280
- Updated
- 2021/12/16
- Product number
- BIPG1011
- Product name
- Ald-PEG3-Azide
- Packaging
- 100mg
- Price
- $546
- Updated
- 2021/12/16
Ald-PEG3-Azide Chemical Properties,Usage,Production
Description
Ald-CH2-PEG3-azide is a click chemistry PEG linker. Aldehyde groups are likely to undergo nucleophile substitution, reduction and oxidation reactions. The azideN3 enable Click Chemistry reactions with alkynes, DBCO and BCN to form triazole groups. PEG3 spacer increases the water solubility of the compound.
Biological Activity
Ald-CH2-PEG3-azide is a cleavable 3-unit PEG-containing ADC linker that can be used to synthesize antibody drug conjugates (ADCs),it is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
target
| Cleavable
| PEGs
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