TBCA antibody
Applications Immunogen Background- Product Name
- TBCA antibody
- Chemical Name
- TBCA antibody
- Synonyms
- TBCA antibody
- CBNumber
- CB56228212
- Formula Weight
- 0
- MOL File
- Mol file
TBCA antibody Chemical Properties,Usage,Production
Applications
TBCA antibody has been tested by ELISA, Western blot, ICC/IF and FACS analysis to assure specificity and reactivity.
Immunogen
Anti-human TBCA mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TBCA amino acids 1-108 purified from E. coli.
Background
TBCA is a tubulin-folding protein which is involved in the early step of the tubulin folding pathway. TBCA is one of four proteins (cofactors A, D, E, and C) implicated in the pathway directing to properly folded beta-tubulin from folding intermediates. Cofactors A and D are thought to be a factor in capturing and stabilizing beta-tubulin in a quasi-native confirmation. TBCA is crucial for cell viability, if reduced it causes a decrease in the amount of soluble tubulin, alterations in microtubules and G1 cell cycle arrest. Cofactor E attaches to the cofactor D-tubulin complex, afterward, interaction with cofactor C triggers the release of tubulin polypeptides that are committed to the native state.
TBCA antibody Preparation Products And Raw materials
Raw materials
Preparation Products
TBCA antibody Suppliers
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