2-AMINO-5-BROMOPYRAZINE-3-CARBOXYLIC ACID, METHYL ESTER Property

Melting point:

164-166°C

storage temp. 

Refrigerator, Under Inert Atmosphere

solubility 

Chloroform, Ethyl Acetate, Methanol

form 

Solid

color 

Orange

Hazard and Precautionary Statements (GHS)

2-AMINO-5-BROMOPYRAZINE-3-CARBOXYLIC ACID, METHYL ESTER Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

2-Amino-5-bromopyrazine-3-carboxylic Acid Methyl Ester is used as the starting material in the preparation of pyrazine derivatives that are AxI and c-Met receptor enzyme inhibitors. These inhibitors are useful in the treatment of tumors. 2-Amino-5-bromopyrazine-3-carboxylic Acid Methyl Ester is also used in the preparation of potent and selective inhibitors of ataxia telangiectasia mutated and Rad3 related (ATR) protein kinase as potential anticancer agents.