ChemicalBook > CAS DataBase List > Sennoside A

Sennoside A

Product Name
Sennoside A
CAS No.
81-27-6
Chemical Name
Sennoside A
Synonyms
Pursenni;SENNOSIDA;Glysennid;SENNOSIDE;PURSENNID;Nsc 112929;GLYSENNIDE;PURSENNIDE;SENNOSIDE A;Sennoside A1
CBNumber
CB5663235
Molecular Formula
C42H38O20
Formula Weight
862.74
MOL File
81-27-6.mol
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Sennoside A Property

Melting point:
>191oC (dec.)
alpha 
D20 -164° (c = 0.1 in 60% acetone); D20 -147° (c = 0.1 in 70% acetone); D20 -24° (c = 0.2 in 70% dioxane)
Boiling point:
1144.8±65.0 °C(Predicted)
Density 
1.743±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Aqueous Base (Slightly, Heated), DMSO (Slightly, Heated)
form 
Solid
pka
3.31±0.40(Predicted)
color 
Yellow to Dark Yellow
BRN 
5723746
Stability:
Hygroscopic
InChIKey
IPQVTOJGNYVQEO-KGFNBKMBSA-N
LogP
1.880 (est)
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Safety

Risk Statements 
22
Safety Statements 
22-45
WGK Germany 
3
F 
3-10
HS Code 
29173990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
68909
Product name
Sennoside A
Purity
analytical standard
Packaging
5mg
Price
$144
Updated
2024/03/01
Sigma-Aldrich
Product number
PHL89276
Product name
Sennoside A
Purity
phyproof? Reference Substance
Packaging
20MG
Price
$454
Updated
2024/03/01
Sigma-Aldrich
Product number
68909
Product name
Sennoside A
Purity
analytical standard
Packaging
25mg
Price
$544
Updated
2024/03/01
Sigma-Aldrich
Product number
1612018
Product name
Sennoside A
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
20mg
Price
$577
Updated
2024/03/01
Sigma-Aldrich
Product number
01870575
Product name
Sennoside A
Purity
primary reference standard
Packaging
25MG
Price
$606
Updated
2023/06/20
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Sennoside A Chemical Properties,Usage,Production

Chemical Properties

Light yellow powder

Uses

a natural anthroquinonone glucoside calcium complex with laxative properties

Uses

Sennoside A is used as a laxative in the treatment of constipation. In addition. it is hypothesized to induce cell proliferation and may be a potential carcinogenic agent.

Definition

ChEBI: Sennoside A is a member of the class of sennosides that is rel-(9R,9'R)-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid which is substituted by hydroxy groups at positions 4 and 4', by beta-D-glucopyranosyloxy groups at positions 5 and 5', and by oxo groups at positions 10 and 10'. The exact stereochemisty at positions 9 and 9' is not known - it may be R,R (as shown) or S,S. It is a member of sennosides and an oxo dicarboxylic acid.

Purification Methods

Sennoside A (bianthraquinonyl-bis-glucoside R,R-enantiomer) [81-27-6] M 862.7, m 220 -2 4 0o(dec), [ ] D -164o (c 0.1, Me2CO/H2O 6:4), [ ] D -24o (c 0.2, 70% aqueous dioxane). Sennoside A forms yellow crystals from aqueous acetone, 2-ethoxyethanol or large volumes of H2O. [Stoll et al. Helv Chim Acta 32 1896 1900, Beilstein 17 III/IV 3403.]

Sennoside A Preparation Products And Raw materials

Raw materials

Preparation Products

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Sennoside A Suppliers

China 256 France 2 Germany 4 India 5 Japan 2 Switzerland 1 United Kingdom 10 United States 32 USA 1 Global 313
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View Lastest Price from Sennoside A manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.
Product
Sennoside A; Senna leaf extract 81-27-6
Price
US $0.00/KG
Min. Order
1KG
Purity
95%-99% HPLC
Supply Ability
1000KG
Release date
2022-09-19
Wuhan Haorong Biotechnology Co.,Ltd
Product
Sennoside A 81-27-6
Price
US $0.00-0.00/kg
Min. Order
20kg
Purity
99%
Supply Ability
200000
Release date
2023-08-15
BINBO BIOLOGICAL CO.,LTD
Product
Sennoside A 81-27-6
Price
US $0.00/kg
Min. Order
1kg
Purity
99.8%
Supply Ability
1000 kg
Release date
2024-04-12

81-27-6, Sennoside ARelated Search:

Sennoside C,Sennoside C Sennoside D,Sennoside D Sennoside B SENNIDINE A 2,2'-DIHYDROXYBENZOPHENONE 4-FORMYL-3-HYDROXYBENZOIC ACID 4-Acetylbenzoic acid 5-ISOPROPYL-3-METHYLPHENOL 4-BROMOBENZHYDROL BIANTHRONYL 4-ETHYL-3-HYDROXYBENZOIC ACID 1,1,2,2-TETRAPHENYLETHANE SENNOSIDE,SENNOSIDE A AND B,SENNOSIDE A AND B,SENNOSIDE 3-Hydroxy-4-methylbenzoic acid HELICIN SENNOSIDES 3-HYDROXY-5-METHYL-BENZOIC ACID 3-ISOBUTYL-BENZOIC ACID

  • Sennoside A std.
  • SENNOSIDEA60%
  • SENNOSIDE A(P)
  • SENNOSIDE A(SH)
  • SENNOSIDA
  • CALCIUM SENNOSIDE 5%, 10%, 20%, 60%
  • [9,9'-Bianthracene]-2,2'-dicarboxylicacid,5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-,(9R,9'R)-
  • Sennoside A1
  • Einecs 201-339-9
  • Nsc 112929
  • SENNIDINE A(RG)
  • Sennoside A ,98%
  • Gentle Nature
  • Glysennid
  • Sennoside A (20 mg)
  • SENNOSIDE A hplc
  • SENNOSIDE A WITH HPLC
  • 11,12-Epoxy-(5Z,8Z,14Z)-eicosatrienoic acid,11,12-EET
  • Pursenni
  • Sennoside A (20 mg) ((9R,9'R)-5,5'-Bis(beta-d-glucopyranosyloxy)-4,4'-dihydroxy-10,10'-dioxo-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid)
  • Sennoside USP
  • GLYSENNIDE
  • SENNOSIDE
  • SENNOSIDE A
  • PURSENNID
  • PURSENNIDE
  • Tomato juice
  • 4,4',10,10'-Tetrahydroxy-5,5'-bis(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-[9,9'-bianthracene]-2,2'-dicarboxylic acid
  • Sennoside A RS
  • 4,4'-dihydroxy-10,10'-dioxo-5,5'-bis((3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-9,9',10,10'-tetrahydro-[9,9'-bianthracene]-2,2'-dicarboxylic acid
  • 81-27-6 Sennoside A
  • Sennoside A ((9R,9''R)-5,5''-Bis(beta-d-glucopyranosyloxy)-4,4''-dihydroxy-10,10''-dioxo-9,9'',10,10''-te (1612018)
  • (9R,9'R)-4,4'-Dihydroxy-10,10'-dioxo-5,5'-bis(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-9,9',10,10'-tetrahydro-[9,9'-bianthracene]-2,2'-dicarboxylic acid
  • Sennoside A (6CI, 7CI, 8CI)
  • (9R,9'R)-4,4'-Dihydroxy-10,10'-dioxo-5,5'-bis(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-9,9',10,10'-tetrahydro-[9,9'-bianthracene]-2,2'-dicarboxylic acid
  • Sennoside A(AS)
  • 81-27-6
  • SA - SM
  • Analytical Standards
  • Alphabetic
  • Analytical Chromatography Product Catalog
  • The group of Sennosides
  • Anthraquinones, Hydroquinones and Quinones
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Inhibitors