ChemicalBook > CAS DataBase List > R(+)-Baclofen.Hydrochloride

R(+)-Baclofen.Hydrochloride

Product Name
R(+)-Baclofen.Hydrochloride
CAS No.
63701-55-3
Chemical Name
R(+)-Baclofen.Hydrochloride
Synonyms
R(+)-BACLOFEN HCL;STX-209 HYDROCHLORIDE;d-baclofenhydrochloride;Arbaclofen hydrochloride;R(+)-BACLOFEN HYDROCHLORIDE;(+)-Baclofen (hydrochloride);(r)-baclofenmonohydrochloride;Arbaclofen hydrochloride salt;Baclofen (R)-(+)- hydrochloride;R(+)-BACLOFENHYDROCHLORIDE(FORR&DONLY)
CBNumber
CB5665769
Molecular Formula
C10H13Cl2NO2
Formula Weight
250.12
MOL File
63701-55-3.mol
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R(+)-Baclofen.Hydrochloride Property

Melting point:
220~222℃
storage temp. 
Store at -20°C
solubility 
DMSO: >20 mg/mL
form 
solid
color 
white
optical activity
[α]28/D +3.8°, c = 0.9 in methanol(lit.)
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Safety

Safety Statements 
24/25
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
RTECS 
MW5084350
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
G013
Product name
R(+)-Baclofen hydrochloride
Purity
solid
Packaging
25mg
Price
$214.7
Updated
2025/07/31
Sigma-Aldrich
Product number
G013
Product name
R(+)-Baclofen hydrochloride
Purity
solid
Packaging
100mg
Price
$706
Updated
2025/07/31
Sigma-Aldrich
Product number
G013
Product name
R(+)-Baclofen hydrochloride
Purity
solid
Packaging
500mg
Price
$2630
Updated
2025/07/31
TRC
Product number
B108005
Product name
R(+)-Baclofen hydrochloride
Packaging
10mg
Price
$40
Updated
2021/12/16
TRC
Product number
B108005
Product name
R(+)-Baclofen hydrochloride
Packaging
25mg
Price
$85
Updated
2021/12/16
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R(+)-Baclofen.Hydrochloride Chemical Properties,Usage,Production

Uses

R(+)-Baclofen.Hydrochloride is a derivative of gamma-aminobutyric acid primarily used to treat spasticity.

Biochem/physiol Actions

R(+)-Baclofen is a GABAB receptor agonist; more active enantiomer; skeletal muscle relaxant.

in vivo

(R)-Baclofen hydrochloride (STX 209 hydrochloride) suppresses audiogenic seizures in the Fmr1-knockout mouse on the seizure-resistant C57BL/6 background with an effective dose of 1 mg/kg[3].
Acute intraperitoneal administration of (R)-Baclofen hydrochloride significantly reduces the percent of mice displaying seizures (seizure incidence), with a minimum effective dose (MED) of 1.5 mg/kg[3].

R(+)-Baclofen.Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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R(+)-Baclofen.Hydrochloride Suppliers

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