ChemicalBook > CAS DataBase List > R(+)-Baclofen.Hydrochloride
R(+)-Baclofen.Hydrochloride
- Product Name
- R(+)-Baclofen.Hydrochloride
- CAS No.
- 63701-55-3
- Chemical Name
- R(+)-Baclofen.Hydrochloride
- Synonyms
- R(+)-BACLOFEN HCL;STX-209 HYDROCHLORIDE;d-baclofenhydrochloride;Arbaclofen hydrochloride;R(+)-BACLOFEN HYDROCHLORIDE;(+)-Baclofen (hydrochloride);(r)-baclofenmonohydrochloride;Arbaclofen hydrochloride salt;Baclofen (R)-(+)- hydrochloride;R(+)-BACLOFENHYDROCHLORIDE(FORR&DONLY)
- CBNumber
- CB5665769
- Molecular Formula
- C10H13Cl2NO2
- Formula Weight
- 250.12
- MOL File
- 63701-55-3.mol
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R(+)-Baclofen.Hydrochloride Property
- Melting point:
- 220~222℃
- storage temp.
- Store at -20°C
- solubility
- DMSO: >20 mg/mL
- form
- solid
- color
- white
- optical activity
- [α]28/D +3.8°, c = 0.9 in methanol(lit.)
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Safety
- Safety Statements
- 24/25
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- MW5084350
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- G013
- Product name
- R(+)-Baclofen hydrochloride
- Purity
- solid
- Packaging
- 25mg
- Price
- $214.7
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- G013
- Product name
- R(+)-Baclofen hydrochloride
- Purity
- solid
- Packaging
- 100mg
- Price
- $706
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- G013
- Product name
- R(+)-Baclofen hydrochloride
- Purity
- solid
- Packaging
- 500mg
- Price
- $2630
- Updated
- 2025/07/31
TRC
- Product number
- B108005
- Product name
- R(+)-Baclofen hydrochloride
- Packaging
- 10mg
- Price
- $40
- Updated
- 2021/12/16
TRC
- Product number
- B108005
- Product name
- R(+)-Baclofen hydrochloride
- Packaging
- 25mg
- Price
- $85
- Updated
- 2021/12/16
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R(+)-Baclofen.Hydrochloride Chemical Properties,Usage,Production
Uses
R(+)-Baclofen.Hydrochloride is a derivative of gamma-aminobutyric acid primarily used to treat spasticity.
Biochem/physiol Actions
R(+)-Baclofen is a GABAB receptor agonist; more active enantiomer; skeletal muscle relaxant.
in vivo
(R)-Baclofen hydrochloride (STX 209 hydrochloride) suppresses audiogenic seizures in the Fmr1-knockout mouse on the seizure-resistant C57BL/6 background with an effective dose of 1 mg/kg[3].
Acute intraperitoneal administration of (R)-Baclofen hydrochloride significantly reduces the percent of mice displaying seizures (seizure incidence), with a minimum effective dose (MED) of 1.5 mg/kg[3].
R(+)-Baclofen.Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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R(+)-Baclofen.Hydrochloride Suppliers
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