ChemicalBook > CAS DataBase List > Schisandrin A

Schisandrin A

Product Name
Schisandrin A
CAS No.
61281-38-7
Chemical Name
Schisandrin A
Synonyms
WUWEIZISU A;SCHIZANDRIN A;SCHISANDRIN A;Doxyschizandrin;DEOXYSCHISANDRIN;DEOXYSCHIZANDRIN;DiMethylgoMisin J;R(+) SCHISANDRIN A;R(+) SCHIZANDRIN A;(+)-Deoxyschisandrin
CBNumber
CB5670585
Molecular Formula
C24H32O6
Formula Weight
416.51
MOL File
61281-38-7.mol
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Schisandrin A Property

Melting point:
116-117 °C
Boiling point:
544.2±50.0 °C(Predicted)
Density 
1.080±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
powder
color 
White to Off-White
LogP
5.870 (est)
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Safety

Safety Statements 
24/25
WGK Germany 
3
RTECS 
HP1595000
HS Code 
29093090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SMB00368
Product name
Schisandrin A
Purity
≥98% (HPLC)
Packaging
10mg
Price
$109
Updated
2023/06/20
Sigma-Aldrich
Product number
90139
Product name
Schisandrin A
Purity
analytical standard
Packaging
50mg
Price
$390
Updated
2022/05/15
TCI Chemical
Product number
C3501
Product name
Schisandrin A
Packaging
25MG
Price
$163
Updated
2023/06/20
TCI Chemical
Product number
C3501
Product name
Schisandrin A
Packaging
100MG
Price
$447
Updated
2023/06/20
Cayman Chemical
Product number
19849
Product name
Schisandrin A
Purity
≥98%
Packaging
5mg
Price
$43
Updated
2023/06/20
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Schisandrin A Chemical Properties,Usage,Production

Description

Schisandrin A is a lignan that has been found in Schisandra and has diverse biological activities. It binds to adiponectin receptor 2 (IC50 = 3.2 μM). Schisandrin A (10, 20, and 50 μM) reduces LPS-induced production of nitric oxide (NO), IL-6, and TNF-α and apoptosis in primary mouse microglial cells. It reverses P-glycoprotein-mediated doxorubicin resistance in MCF-7/dox cells when used at a concentration of 20 μM. Schisandrin A (4, 12, and 36 mg/kg) reverses short-term and spatial memory deficits, as well as decreases in cerebral superoxide dismutase (SOD) and glutathione peroxidase (GPX) activities induced by amyloid β (1-42) (Aβ42; ) in a mouse model of Alzheimer’s disease.

Chemical Properties

White powder

Uses

Schizandrin A is an extract from Schisandra chinesis. a dibenzocyclooctadiene lignan with antiinflammatory activity.

Schisandrin A Preparation Products And Raw materials

Raw materials

Preparation Products

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61281-38-7, Schisandrin ARelated Search:


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  • DEOXYSCHIZANDRIN SCHISANDRIN A
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  • Deoxyschizandrin, 98%, from Schisandra chinensis (Turcz.) Baill.
  • Dibenzo[a,c]cyclooctene, 5,6,7,8-tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-, (6R,7S,12aR)-
  • (6R,7S,12aR)-5,6,7,8-Tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyldibenzo[a,c]cyclooctene
  • Inhibitor,Schisandrin A,Cytochrome P450,Schizandrin-A,Autophagy,Deoxyschizandrin,Virus Protease,inhibit,Wuweizisu-A,Schizandrin A,CYPs
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