Asiaticoside

Product Name: Asiaticoside
CAS No.: 16830-15-2
Chemical Name: Asiaticoside
Synonyms: Asiaticosides;asiaticosid;MADECASSOL;dermatologico;blastoestimulina;2-alpha,3-beta,23-trihydroxy-urs-12-en-28-oicacio-6-deoxy-alpha-l-mannopy;Ba-2742;CENTELASE;MADECASOL;Meal snow
CBNumber: CB7109339
Molecular Formula: C48H78O19
Formula Weight: 959.12
MOL File: 16830-15-2.mol

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Asiaticoside Property

Melting point:: 235-238°C
alpha: D20 -14° (alc)
Boiling point:: 1017.5±65.0 °C(Predicted)
Density: 1.44±0.1 g/cm3(Predicted)
vapor pressure: 0.001Pa at 160℃
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: DMSO (Slightly), Ethanol (Slightly, Heated, Sonicated), Methanol (Slightly)
pka: 12.50±0.70(Predicted)
form: Solid
color: Crystals
Water Solubility: 99mg/L
InChIKey: WYQVAPGDARQUBT-KRQXBQLUNA-N
LogP: 0.44 at 22℃
CAS DataBase Reference: 16830-15-2(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3
RTECS: YU9625000
F: 1-10
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0001206
Product name: Asiaticoside
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 40 mg
Price: $164
Updated: 2025/07/31

Sigma-Aldrich

Product number: 43191
Product name: Asiaticoside
Purity: analytical standard
Packaging: 5mg
Price: $170
Updated: 2025/07/31

Sigma-Aldrich

Product number: 1043331
Product name: Asiaticoside
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 30mg
Price: $448
Updated: 2025/07/31

Sigma-Aldrich

Product number: 04560590
Product name: Asiaticoside
Purity: primary pharmaceutical reference standard
Packaging: 10mg
Price: $510
Updated: 2025/07/31

Sigma-Aldrich

Product number: 43191
Product name: Asiaticoside
Purity: analytical standard
Packaging: 1mg
Price: $33.7
Updated: 2022/05/15

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Asiaticoside Chemical Properties,Usage,Production

Description

Asiaticoside is the main saponin constituent of C. asiatica, a plant long used in the Ayurvedic system of medicine to treat a variety of ailments including dermatitis, diabetes, cough, cataract, hypertension, as well as for wound healing and improving memory. In various wound healing models, topical application (0.2-0.4%), injection (1 mg), or ingestion (1 mg/kg) of asiaticoside has been shown to increase hydroxyproline content, improve tensile strength, increase collagen synthesis and remodeling of the collagen matrix, promote epithelialization, stimulate glycosaminoglycan synthesis, and elevate antioxidant levels.

Chemical Properties

White powder

Uses

wound healing, anxiolytic

Uses

Asiatic Acid is a terpenoid saponin component isolated from Centella asiatica with antioxidant and anti-inflammatory activities. Asiaticoside has been shown to possess strong wound-healing properties and reduces scar formation.

Definition

ChEBI: Asiaticoside is a triterpenoid saponin.

Flammability and Explosibility

Not classified

Biological Activity

Asiaticoside, a triterpenoid compound from Centella asiatica, has been shown to have anti-inflammatory, anti-renal fibrosis and tissue repair promoting effects. Asiaticoside has been shown through ex vivo and in vivo studies to reduce blood urea nitrogen (BUN) and serum creatinine (Scr) levels in a renal ischemia-reperfusion injury (IRI) model^[1]. Meanwhile, Asiaticoside decreased the secretion of IL-6, IL-1β, and TNF-α, but increased the secretion of IL-10 using a dose-dependent manner. Treatment of Raw264.7 cells with lipopolysaccharide (LPS) induced an inflammatory response, but the LPS-induced effect was attenuated by the administration of asiaticoside. In addition, asiaticoside significantly inhibits LPS-induced expression of inducible nitric oxide synthase (iNOS) and promotes expression of the polarisation marker protein arginase 1. It is also a potential candidate for use as a dental wound healing agent with a maximum tolerated concentration of 0.25 mg/ml, and its mechanism of action may be related to increased Col1A1 gene expression ^[2].

Safety Profile

Questionable carcinogen withexperimental tumorigenic data. When heated todecomposition it emits acrid smoke and fumes. Promoteshealing of wounds.

storage

+4°C

References

[1] XINGYING ZHAO, JINGWEN ZHOU*; Elucidation of the Biosynthesis of Asiaticoside and Its Reconstitution in Yeast[J]. ACS Sustainable Chemistry & Engineering, 2024, 12 10: 4028-4040. DOI:10.1021/acssuschemeng.3c07046.
[2] W. H. SURIYAH. In Vitro Wound Healing Effect of Asiaticoside Extracted from Centella asiatica (‘Pegaga’) on Human Gingival Fibroblast Cell Line[J]. Materials Science Forum, 2021, 72 1: 224-229. DOI:10.4028/www.scientific.net/MSF.1025.224.

Asiaticoside Preparation Products And Raw materials

Raw materials

PETROLEUM ETHER

Preparation Products

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Asiaticoside Suppliers

Belgium 1 Brazil 1 Canada 1 China 500 Czech Republic 1 Egypt 1 Europe 2 France 2 Germany 5 India 9 Italy 1 Japan 1 Poland 1 Switzerland 2 United Kingdom 7 United States 45 Global 580

Shaanxi Haochen Biological Technology Co., Ltd.

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Hangzhou Linran Biotechnology Co. LTD

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Nanjing bingcheng Biotechnology Co., Ltd.

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Shaanxi xintianyu Biotechnology Co., Ltd.

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Xi'an Hongtaiyuan Biotechnology Co., Ltd

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Xi'an Tianlangyuan Biotechnology Co., Ltd.

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Xi`an Tian Guangyuan Biotech Co., Ltd.

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J & K SCIENTIFIC LTD.

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Chembest Research Laboratories Limited

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Beijing HwrkChemical Technology Co., Ltd

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View Lastest Price from Asiaticoside manufacturers

Lianyungang Kaiyu Environmental Tech Co., Ltd.

Product: Asiaticoside 16830-15-2
Price: US $1200.00-1100.00/ton
Min. Order: 1ton
Purity: 99%
Supply Ability: 1000T/M
Release date: 2025-10-14

Hebei Chuanghai Biotechnology Co., Ltd

Product: Asiaticoside 16830-15-2
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2025-06-26

Anhuyan (Hainan) Biotechnology Co., LTD

Product: Asiaticoside 16830-15-2
Price: US $0.00-0.00/g
Min. Order: 0.001g
Purity: 99.99%
Supply Ability: 2000000t
Release date: 2025-06-11

16830-15-2, AsiaticosideRelated Search:

METSULFURON METHYL Asiaticoside Kresoxim-methyl Methyl acetate Bensulfuron methyl Methyl salicylate Methylparaben Rotundine Sophoricoside Ursolic acid Asiaticoside B Centella asiatica extract Thiophanate-methyl Methyl Centella asiatica whole plant GLYCEROL MONOISOSTEARATE Methyl bromide Hydroxy asiaticoside Madecassol

2-alpha,3-beta,23-trihydroxy-urs-12-en-28-oicacio-6-deoxy-alpha-l-mannopy

asiaticosid

blastoestimulina

dermatologico

ranosyl-(1-4)-o-beta-d-glucopyranosyl-(1-6)-o-beta-d-glucopyranosylester

CENTELASE

ASIATICOSIDE

MADECASOL

MADECASSOL

[6-[[3,4-Dihydroxy-6-(hydroxymethyl)-5-(3,4,5-trihydroxy-6-methyl-oxan-2-yl)oxy-oxan-2-yl]oxymethyl]-3,4,5-trihydroxy-oxan-2-yl] (1S,2R,4aS,6aS,6bR,9S,10R,11R,12aS,14bR)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate

Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, O-6-deoxy-.alpha.-L-mannopyranosyl-(1?4)-O-.beta.-D-glucopyranosyl-(1?6)-.beta.-D-glucopyranosyl ester, (2.alpha.,3.beta.,4.alpha.)-

ASIATICOSIDE(P)

Gotu Kola (Centella Asiatica) (40%Asiatisides)

Urs-12-en-28-oic acid,2,3,23-trihydroxy-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranos

yl-(1→6)- β-D-glucopyranosyl ester, (2α,3β,4α)-

O-6-Deoxy-a-L-mannopyranosyl-(1->4)-O-b-D-glucopyranosyl-(1->6)-b-D-glucopyranosyl (2a,3b,4a)-2,3,23-trihydroxyurs-12-en-28-oate

O-6-Deoxy-a-L-mannopyranosyl-(1->4)-O-b-D-glucopyranosyl-(1->6)-b-D-glucopyranosyl ester, (2a,3b,4a)-

(4R)-2α,3β,23-Trihydroxyurs-12-en-28-oic acid [6-O-[4-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]-β-D-glucopyranosyl] ester

2α,3β,23-Trihydroxyurs-12-en-28-oic acid 6-O-[4-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]-β-D-glucopyranosyl ester

Ba-2742

Asiaticosides

Centella Asiatica(40%Asiatisides)

ASIATICOSIDE hplc

ASIATICOSIDE WITH HPLC

Asiaticoside,Madecassol

Asiaticoside Gotu Kola Extract

(1S,2R,4aS,6aS,6bR,9S,10R,11R,12aS,14bR)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate

BlastostiMulina

EMdecassol

Marticassol

Asiaticoside (30 mg)

Asiaticoside, froM Centella asiatica

Asiaticoside 16830-15-2

Centella asiatica extractTriterpenoid saponins

Total Triterpenes of centella asiatica extract

Asiaticoside(Single)

(1S,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid [(2S,3R,4S

Centella asiatica Extract Asiaticoside powder

Meal snow

Asiaticoside, 98%, from Centella asiatica (L.) Urb.

Asiaticoside, >=98%

Asiaticosides 10%-80%

Asiaticoside CRS

BRN0078195

CCRIS8995

NSC166062

Asiaticoside,90%

Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, (2α,3β,4α)-

Asiaticoside USP/EP/BP

Centella asiatica powder

Asiaticoside/Centella asiatica

asiaticcoside

Asiaticoside (6CI)

(1S,2R,4aS,6aS,6bR,8aR,9R,10R,11R,12aR,12bR,14bS)-(2S,3R,4S,5S,6R)-6-((((2R,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl 10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate

Centella Total Glucosides, CTG

Asiaticoside-RM

O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl (2α,3β,4α)-2,3,23-trihydroxyurs-12-en-28-oate

Asiaticoside, 10 mM in DMSO