Sophoricoside

Product Name: Sophoricoside
CAS No.: 152-95-4
Chemical Name: Sophoricoside
Synonyms: Sophomoric;ISOGENISTIN;SOPHORICOSIDE;Sophoricoside(P);Sophoricoside-RM;Sophoricoside >SOLSTITIALIN A(SH);Sophoricoside ,98%;Sophora glycosides;GENISTEIN-4'-GLUCOSIDE
CBNumber: CB7446261
Molecular Formula: C21H20O10
Formula Weight: 432.38
MOL File: 152-95-4.mol

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Sophoricoside Property

Melting point:: 298°
alpha: D20 -47° (pyridine); D20 -32° (10% aq pyridine)
Boiling point:: 466.08°C (rough estimate)
Density: 1.3597 (rough estimate)
refractive index: 1.5376 (estimate)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: Aqueous Base (Slightly), DMSO (Slightly, Heated), Pyridine (Slightly, Sonicated)
pka: 6.45±0.20(Predicted)
form: Solid
color: White to Light Brown
λmax: 271nm(MeOH)(lit.)
InChIKey: ISQRJFLLIDGZEP-JNAFRSBINA-N
SMILES: C12C(O)=CC(O)=CC=1OC=C(C1C=CC(O[C@H]3[C@H](O)[C@H]([C@H](O)[C@@H](CO)O3)O)=CC=1)C2=O |&1:16,17,19,20,22,r|
CAS DataBase Reference: 152-95-4(CAS DataBase Reference)

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Safety

Safety Statements: 22-24/25
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SMB00438
Product name: Sophoricoside
Purity: ≥98% (HPLC)
Packaging: 5 mg
Price: $161
Updated: 2025/07/31

Sigma-Aldrich

Product number: SMB00438
Product name: Sophoricoside
Purity: ≥98% (HPLC)
Packaging: 25 mg
Price: $476
Updated: 2025/07/31

TCI Chemical

Product number: S0835
Product name: Sophoricoside
Purity: >98.0%(HPLC)
Packaging: 100mg
Price: $230
Updated: 2025/07/31

Usbiological

Product number: 300997
Product name: Sophoricoside
Packaging: 20mg
Price: $276
Updated: 2021/12/16

Usbiological

Product number: 294604
Product name: Sophoricoside
Packaging: 100mg
Price: $333
Updated: 2021/12/16

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Sophoricoside Chemical Properties,Usage,Production

Chemical Properties

Light yellow solid

Uses

Genistein 4''-β-D-glucopyranoside is a metabolite of Genistein (G350000), which exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation.

Definition

ChEBI: Sophoricoside is an isoflavonoid and an acrovestone.

Biological Activity

Sophoricoside (SOP) improves lipopolysaccharides (LPS)-induced acute lung injury (ALI) in mice by activating the adenosine monophosphate-activated protein kinase (AMPK)/nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway. It also improves contact dermatitis by inhibiting the nuclear factor-kappa B (NF-KB) pathway in B cells in mice model.', 'Sophoricoside elicits anti-cancer, immunosuppressive, and anti-inflammatory activities. It inhibits proinflammatory cytokine production in human mast cells and has the potential to tre at allergic inflammation diseases.

in vivo

When the Sophoricoside is orally administered 1 h before compound 48/80 injections, the scratching behaviors is reduced. The inhibition rate of Sophoricoside (2 mg/kg) is approximately 41.21%. Orally administered Sophoricoside inhibits the scratching behaviors by 47.31%. When mice are treated for 2 weeks with Sophoricoside, the atopic dermatitis is recovered to a significant extent^[1].

Sophoricoside Preparation Products And Raw materials

Raw materials

Preparation Products

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Sophoricoside Suppliers

China 268 Germany 2 India 2 Japan 1 United Kingdom 6 United States 28 Global 307

Shanxi Yuning Biotechnology Co., Ltd.

Tel: 13623677056
Email: 1639455302@qq.com
Country: China
ProdList: 303
Advantage: 58

Nanjing bingcheng Biotechnology Co., Ltd.

Tel: 18805194892
Email: 2727751293@qq.com
Country: China
ProdList: 170
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Aktin Chemicals, Inc.

Tel: 86-28-85159085
Fax: 86-28-85152372
Email: info@aktinchem.com
Country: China
ProdList: 297
Advantage: 62

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View Lastest Price from Sophoricoside manufacturers

BINBO BIOLOGICAL CO.,LTD

Product: Sophoricoside 152-95-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 10% 20% 98%
Supply Ability: 1000 kg
Release date: 2025-06-09

Shaanxi Xianhe Biotech Co., Ltd

Product: Sophoricoside 152-95-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 1000kg
Release date: 2025-04-29

Changsha Staherb Natural Ingredients Co., Ltd.

Product: Sophoricoside 152-95-4
Price: US $80.00-750.00/kg
Min. Order: 1kg
Purity: 5%-98% HPLC
Supply Ability: 10000KG
Release date: 2022-09-19

152-95-4, SophoricosideRelated Search:

SOPHORIDINE Sophoridine Tea polyphenol Naringin Ginkgo biloba extract Polydatin Evodiamine PINOCEMBRIN CALYCOSIN Quercetin dihydrate Rotundine Tris(hydroxymethyl)nitromethane Solvent Red 43 Tangeretin Genistein 5,7-DIHYDROXYISOFLAVONE 5,4'-DIHYDROXY-7-METHOXYISOFLAVONE-4'-O-GLUCOSIDE Sophoricoside

5,7-dihydroxy-3-[4-[[3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]phenyl]-1-benzopyran-4-one

SOPHORICOSIDE

ISOGENISTIN

GENISTEIN-4'-GLUCOSIDE

GENISTEIN-4'-O-GLUCOSIDE

4H-1-Benzopyran-4-one,3-[4-(β-

D-glucopyranosyloxy)phenyl]-5,7-dihydroxy-

Sophoricoside ,98%

3-[4-(β-D-Glucopyranosyloxy)phenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one

SOLSTITIALIN A(SH)

Genistein 4'-Glucoside 4'-(beta-D-Glucopyranosyloxy)-5,7-dihydroxyisoflavone

5,7-dihydroxy-3-[4-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]chromen-4-one

4'-beta-D-glucopyranosyloxy-5,7-dihydroxyisoflavone

Sophora glycosides

Sophoricoside 5,7-Dihydroxy-3-[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]chromen-4-one

Sophoricoside, 98%, from Sophora japonica Linn.

Sophoricoside &gt

Genistein 4'-β-D-glucopyranoside

Genistein sophoricoside

4H-1-Benzopyran-4-one, 3-[4-(β-D-glucopyranosyloxy)phenyl]-5,7-dihydroxy-

Sophoricoside USP/EP/BP

5,7-Dihydroxy-3-(4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-4H-chromen-4-one

Sophomoric

4H-1-Benzopyran-4-one,3-[4-(b-D-glucopyranosyloxy)phenyl]-5,7-dihydroxy-

SOPHORICOSIDE(GENISTEIN-4'-GLUCOSIDE)

Sophoricoside(P)

Sophoricoside-RM

Sophoricoside, 10 mM in DMSO

Genistein 4'-beta-D-glucopyranoside

152-95-4

152-94-5

Miscellaneous Natural Products

Natural Plant Extract