ChemicalBook > CAS DataBase List > Cytochalasin H

Cytochalasin H

Product Name
Cytochalasin H
CAS No.
53760-19-3
Chemical Name
Cytochalasin H
Synonyms
paspalin;Nsc305222;paspalinpi;Aids031241;Paspalin P1;Aids-031241;CYTOCHALASIN H;19-triene-1-one;kodocytochalasin-1;Cytochalasin H(CytH)
CBNumber
CB5672741
Molecular Formula
C30H39NO5
Formula Weight
493.63
MOL File
53760-19-3.mol
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Cytochalasin H Property

Melting point:
252-258 °C
Boiling point:
587°C (rough estimate)
Density 
1.1369 (rough estimate)
refractive index 
1.6310 (estimate)
storage temp. 
2-8°C
solubility 
chloroform: 10 mg/mL, clear, colorless
pka
13.88±0.70(Predicted)
form 
A lyophilisate
color 
Long needles from CHCl3/Et2O
BRN 
1632647
InChIKey
NAEWXXDGBKTIMN-QHDZSFFESA-N
LogP
4.758 (est)
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Safety

Hazard Codes 
T+
Risk Statements 
26/27/28-63
Safety Statements 
28-36/37-45
RIDADR 
UN 3462 6.1/PG 2
WGK Germany 
3
RTECS 
HA5306000
F 
10
HazardClass 
6.1(a)
PackingGroup 
I
Toxicity
cyt-hmn:lym 50 mg/L IJEBA6 16,430,78
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C0889
Product name
Cytochalasin H from Phomopsis sp.
Packaging
5mg
Price
$1090
Updated
2023/01/07
Cayman Chemical
Product number
18434
Product name
Cytochalasin H
Purity
≥95%
Packaging
1mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
18434
Product name
Cytochalasin H
Purity
≥95%
Packaging
5mg
Price
$430
Updated
2024/03/01
TRC
Product number
C998715
Product name
CytochalasinH(>90%)
Packaging
1mg
Price
$110
Updated
2021/12/16
Usbiological
Product number
C9093-50H
Product name
Cytochalasin H
Packaging
1mg
Price
$368
Updated
2021/12/16
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Cytochalasin H Chemical Properties,Usage,Production

Uses

Cytochalasin H is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, resulting in pronounced morphogenic changes in animals and plants. In vitro, cytochalasin H exhibits antibacterial, antifungal, nematocidal and antitumour activity.

Safety Profile

Poison by intravenous and intraperitoneal routes. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

in vivo

Cytochalasin H (2.5 mg/kg; i.p.) can delay the growth of A549 xenograft tumors in Balb/cnu/nu mice[2].

Animal Model:male Balb/cnu/nu mice with A549 xenograft[2]
Dosage:2.5 mg/kg
Administration:intraperitoneal injection; 3 injections/week,for 80 days
Result:Attenuated tumor growth in vivo.

storage

+4°C

Cytochalasin H Preparation Products And Raw materials

Raw materials

Preparation Products

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Cytochalasin H Suppliers

China 71 Germany 2 India 1 Switzerland 1 United Kingdom 4 United States 9 USA 1 Global 89
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
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China
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
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Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
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China
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4729
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58
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 1316706386
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
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Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
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AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
Country
China
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2990
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Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
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China
ProdList
4601
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Guangzhou Zhiya Chemdrugs Co.,Ltd
Tel
18122150900
Fax
QQ:2869377561
Email
sculk28@163.com
Country
China
ProdList
646
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Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
17687
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Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
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58

53760-19-3, Cytochalasin HRelated Search:

NONANAMIDE 3-METHYL-1-PENTEN-3-OL DECANAMIDE 2,3-DIMETHYLCYCLOHEXANOL Formetorex 3-AMINO-2,2-DIMETHYL-1-PROPANOL (R)-(-)-PENTEN-2-OL 2-Nonanamine 2-Pyrrolidinone,4-methyl- (S)-2-Aminooctane (2R,5R)-2,5-HEXANEDIOL 5-PHENYL-1-PENTANOL trans-2-Nonen-1-ol N-TERT-BUTYLACETAMIDE 1,3-DIMETHYLBUTYL ACETATE Cytochalasin H CYTOCHALASIN J,cytochalasin J from phomopsis sp. CYTOCHALASIN B, DIHYDRO

  • PASPALIN P1; KODOCYTOCHALASIN 1; CYTOCHALASIN O; NSC305222; 17-DEOXO-21-ACETYLZYGOSPORIN D
  • (11)cytochalasa-6(12),13,19-trien-1-one,21-(acetyloxy)-7,18-dihydroxy-16,18-di
  • (7s,13e,16s,18s,19e,21r)-methyl-10-phenyl
  • 19-triene-1-one
  • 21-acetoxy-7,18-dihydroxy-16,18-dimethyl-10-phenyl-(11)cytochalasa-6(12),13,
  • cytochalasinhfromphomopsissp.
  • kodocytochalasin-1
  • paspalin
  • paspalinpi
  • CYTOCHALASIN H
  • cytochalasin H from A phomopsis species
  • Kodocytochalasin 1, Paspalin P1, 17-Deoxo-21-acetylzygosporin D
  • (7S,13E,16S,18R,19E,21R)-21-Acetyloxy-7,18-dihydroxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6(12),13,19-trien-1-one
  • Paspalin P1
  • Acetic acid 16-benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylene-18-oxo-17-aza-tricyclo[9.7.0.01,15]octadeca-3,9-dien-2-yl ester
  • Aids031241
  • Aids-031241
  • Nsc305222
  • 17-Deoxo-21-acetylzygosporin D
  • Cytochalasin H(CytH)
  • 1H-Cycloundec[d]isoindol-1-one, 15-(acetyloxy)-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-, (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-
  • Cytochalasin H USP/EP/BP
  • Cytochalasin H (>90%)
  • (16-Benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylidene-18-oxo-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-2-yl) acetate
  • Cytochalasin H, 10 mM in DMSO
  • 53760-19-3
  • C30H39NO5
  • Actin Inhibitors and Probes
  • BioChemical
  • Biochemicals and Reagents
  • Cell Biology
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  • Cytoskeleton and Extracellular Matrix
  • Enzyme Inhibitors
  • Enzyme Inhibitors by Type
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  • Other
  • Enzyme Inhibitors
  • Enzyme Inhibitors by Type
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  • Actin Inhibitors and ProbesCell Signaling and Neuroscience
  • Cell Signaling and Neuroscience
  • Cytoskeleton and Extracellular Matrix
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