ChemicalBook > CAS DataBase List > 4,6-DIHYDROXY-2-METHOXYPYRIMIDINE

4,6-DIHYDROXY-2-METHOXYPYRIMIDINE

Product Name
4,6-DIHYDROXY-2-METHOXYPYRIMIDINE
CAS No.
1758-98-1
Chemical Name
4,6-DIHYDROXY-2-METHOXYPYRIMIDINE
Synonyms
2-MethoxypyriMidine-4,6-diol;4,6-Dihydroxy-2-MethoxypyiMidine;2-Methoxy-4,6-dihydroxypyriMidine;4,6-DIHYDROXY-2-METHOXYPYRIMIDINE;4(3H)-Pyrimidinone, 6-hydroxy-2-methoxy-;4(1H)-PyriMidinone, 6-hydroxy-2-Methoxy-;4(1H)-Pyrimidinone, 6-hydroxy-2-methoxy- (9CI);4,6-DIHYDROXY-2-METHOXYPYRIMIDINE ISO 9001：2015 REACH
CBNumber
CB5673874
Molecular Formula
C5H6N2O3
Formula Weight
142.11
MOL File
1758-98-1.mol
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4,6-DIHYDROXY-2-METHOXYPYRIMIDINE Property

Melting point:
193-195℃
Density 
1.51±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
pka
4.39±0.10(Predicted)
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Safety

HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M332993
Product name
2-Methoxypyrimidine-4,6-diol
Packaging
50mg
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
075969
Product name
2-Methoxypyrimidine-4,6-diol
Purity
95+%
Packaging
1g
Price
$185
Updated
2021/12/16
AK Scientific
Product number
W3853
Product name
2-Methoxypyrimidine-4,6-diol
Packaging
5g
Price
$239
Updated
2021/12/16
Matrix Scientific
Product number
075969
Product name
2-Methoxypyrimidine-4,6-diol
Purity
95+%
Packaging
5g
Price
$479
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0388358
Product name
2-METHOXYPYRIMIDINE-4,6-DIOL
Purity
95.00%
Packaging
5MG
Price
$500.15
Updated
2021/12/16
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4,6-DIHYDROXY-2-METHOXYPYRIMIDINE Chemical Properties,Usage,Production

Synthesis

5329-33-9

108-59-8

1758-98-1

General procedure for the synthesis of 4,6-dihydroxy-2-methoxypyrimidines from O-methylisourea hydrochloride and dimethyl malonate: Step 1: Synthesis of 2-methoxy-pyrimidine-4,6-diols In a sealed tube, O-methylisourea hydrochloride (3.0 g, 27 mmol) and dimethyl malonate (3.1 mL, 27 mmol) were dissolved in a 30% w/v sodium methanol solution in methanol. The reaction mixture was heated to reflux for 4 h, followed by cooling to room temperature and allowed to stand overnight. The resulting white precipitate was collected by filtration and dried under vacuum to give 4.2 g (quantitative yield) of 4,6-dihydroxy-2-methoxypyrimidine. 1H NMR (DMSO-d6, 400 MHz) δ: 10.21 (br s, 1H), 4.09 (s, 1H), 3.65 (s, 3H).

References

[1] Patent: WO2007/65940, 2007, A1. Location in patent: Page/Page column 49
[2] Patent: US2012/88755, 2012, A1. Location in patent: Page/Page column 66-67

4,6-DIHYDROXY-2-METHOXYPYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4,6-DIHYDROXY-2-METHOXYPYRIMIDINE Suppliers

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View Lastest Price from 4,6-DIHYDROXY-2-METHOXYPYRIMIDINE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2-MethoxypyriMidine-4,6-diol 1758-98-1
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-13

1758-98-1, 4,6-DIHYDROXY-2-METHOXYPYRIMIDINERelated Search:

4,6-DIHYDROXY-2-METHOXYPYRIMIDINE 4,6-DIHYDROXY-5-METHOXYPYRIMIDINE 5-METHOXYURACIL/2,4-DIHYDROXY-5-METHOXYPYRIMIDINE,2,4-DIHYDROXY-5-METHOXYPYRIMIDINE 2-[(4,6-DIMETHOXYPYRIMIDIN-2-YL)OXY]BENZOIC ACID METHYL 3-FORMYLINDOLE-6-CARBOXYLATE 3-[(4,6-DIMETHOXYPYRIMIDIN-2-YL)OXY]PYRIDINE-2-CARBOXYLIC ACID 4,6-DIHYDROXY-5-METHOXYPYRIMIDINE DISODIUM SALT 3-[(4,6-DIMETHOXYPYRIMIDIN-2-YL)OXY]-N-METHYL-N-PHENYL-2-PYRIDINEMETHANAMINE A-[(4,6-DIMETHOXYPYRIMIDIN-2-YL)OXY]-2,3-DIHYDRO-5-BENZOFURANACETIC ACID, ETHYL ESTER 3-[(4,6-DIMETHOXYPYRIMIDIN-2-YL)OXY]-N-(4-METHOXYPHENYL)-N-METHYL-2-PYRIDINEMETHANAMINE 2-[(4,6-DIMETHOXYPYRIMIDIN-2-YL)OXY]-3-METHYLBUTANOIC ACID 2-[(4,6-DIMETHOXYPYRIMIDIN-2-YL)OXY]-6-METHOXYBENZOIC ACID 2-METHYL-4-[2-[(4,6-DIMETHOXYPYRIMIDIN-2-YL)OXY]PHENYL]PYRIMIDINE 4,6-DIMETHOXY-2-[2-(PYRIMIDIN-4-YL)-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHOXY]PYRIMIDINE 2-[2-(1,3,4-OXADIAZO-2-YL)PHENYLOXY]-4,6-DIMETHOXYPYRIMIDINE 2-[2-(N-METHYLPYRAZOL-3-YL)PHENYLOXY]-4,6-DIMETHOXYPYRIMIDINE METHYL 2-[(4,6-DIMETHOXYPYRIMIDIN-2-YL)OXY]-6-CHLOROBENZOATE 2-[2-(5-METHYL-1,2,4-OXADIAZOLO-3-YL)PHENYLOXY]-4,6-DIMETHOXYPYRIMIDINE

  • 4,6-DIHYDROXY-2-METHOXYPYRIMIDINE
  • 4(1H)-Pyrimidinone, 6-hydroxy-2-methoxy- (9CI)
  • 4,6-Dihydroxy-2-MethoxypyiMidine
  • 2-Methoxy-4,6-dihydroxypyriMidine
  • 2-MethoxypyriMidine-4,6-diol
  • 4(1H)-PyriMidinone, 6-hydroxy-2-Methoxy-
  • 4(3H)-Pyrimidinone, 6-hydroxy-2-methoxy-
  • 4,6-DIHYDROXY-2-METHOXYPYRIMIDINE ISO 9001：2015 REACH
  • 1758-98-1
  • PYRIMIDINE
  • Heterocycle-Pyrimidine series