PHENYLBIGUANIDE

Product Name: PHENYLBIGUANIDE
CAS No.: 102-02-3
Chemical Name: PHENYLBIGUANIDE
Synonyms: p1426;phenyl-biguanid;PHENYLBIGUANIDE;phenyldiguanide;1-PHENYLBIGUANIDE;1-phenyl-biguanid;N-Phenylbiguanide;Phenylbiguanide>n-phenyl-n’-guanylguanidine;2-(N2-Phenylamidino)guanidine
CBNumber: CB5676800
Molecular Formula: C8H11N5
Formula Weight: 177.21
MOL File: 102-02-3.mol

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PHENYLBIGUANIDE Property

Melting point:: 135-142 °C (lit.)
Boiling point:: 299.13°C (rough estimate)
Density: 1.2512 (rough estimate)
refractive index: 1.6900 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: alcohol: freely soluble
pka: 10.76, 2.13(at 25℃)
form: powder to crystal
color: White to Orange to Green
Merck: 14,7276
InChIKey: CUQCMXFWIMOWRP-UHFFFAOYSA-N
CAS DataBase Reference: 102-02-3(CAS DataBase Reference)

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Safety

WGK Germany: 3
RTECS: DU2450000
HS Code: 2925.29.6000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 164216
Product name: 1-Phenylbiguanide
Purity: 98%
Packaging: 25g
Price: $435
Updated: 2025/07/31

TCI Chemical

Product number: P1002
Product name: Phenylbiguanide
Purity: >98.0%(T)
Packaging: 5g
Price: $205
Updated: 2025/07/31

TCI Chemical

Product number: P1002
Product name: Phenylbiguanide
Purity: >98.0%(T)
Packaging: 10g
Price: $347
Updated: 2025/07/31

TRC

Product number: P319933
Product name: 1-Phenylbiguanide
Packaging: 50g
Price: $220
Updated: 2021/12/16

ChemScene

Product number: CS-0021169
Product name: Phenylbiguanide
Purity: >98.0%
Packaging: 100mg
Price: $50
Updated: 2021/12/16

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PHENYLBIGUANIDE Chemical Properties,Usage,Production

Uses

1-Phenylbiguanide is a 5-hydroxytryptamine receptor agonist.

Definition

ChEBI: A member of the class of biguanides that is biguanide in which one of the terminal nitrogen atoms is substituted by a phenyl group.

General Description

1-Phenylbiguanide is a 5-hydroxytryptamine receptor agonist and increases extracellular dopamine release in rat nucleus accumbens in vivo. It serves as building block for synthesis of heterocyclic compounds.

in vivo

In anaesthetised mice, Phenylbiguanide (PBG), a drug that is known to stimulate cardiopulmonary afferent C-fibres,is injected into the right atrium of the heart and mapped c-Fos expression within specific regions of the central nervous system. Intraatrial injection of PBG produces a reflex cardiorespiratory response including a pronounced bradycardia and a respiratory depression^[3].

IC 50

5-HT₃ Receptor: 3 μM (EC₅₀)

Purification Methods

Crystallise the biguanide from water or toluene. [Beilstein 12 H 370, 12 I 236, 12 III 807.]

PHENYLBIGUANIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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PHENYLBIGUANIDE Suppliers

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View Lastest Price from PHENYLBIGUANIDE manufacturers

Career Henan Chemical Co

Product: PHENYLBIGUANIDE 102-02-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2020-03-04

102-02-3, PHENYLBIGUANIDERelated Search:

1,3-Diphenyl-1,1,3,3-tetramethyldisiloxane N,N'-Diphenylurea 1-(4-FLUOROPHENYL)BIGUANIDE HYDROCHLORIDE Biguanide o-Tolyl biguanide N-(4-CHLOROPHENYL)-N'-(ISOPROPYL)-IMIDODICARBONIMIDIC DIAMIDE PHENYLBIGUANIDE 1-PHENYLBIGUANIDE MONOHYDROCHLORIDE,1-PHENYLBIGUANIDE HYDROCHLORIDE 1-(4-TRIFLUOROMETHYL)PHENYLBIGUANIDE HYDROCHLORIDE SALT 96% 4-(TRIFLUOROMETHYL)PHENYLBIGUANIDE HYDROCHLORIDE,1-(4-TRIFLUOROMETHYL)PHENYLBIGUANIDE, H&,1-(4-TRIFLUOROMETHYL)PHENYLBIGUANIDE HYDROCHLORIDE 1-Methyl-1-phenylbiguanide 1-phenylbiguanide, compound with benzothiazole-2(3H)-thione (1:1) PHENYLBIGUANIDE MBT SALT 1G [R] PHENYLBIGUANIDE MBT SALT 1-(A-BENZOYLBENZYLIDENE)-5-PHENYLBIGUANIDE 6,6-DIMETHYL-N2-PHENYL-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE SPECS AG-690/12767754 3-(4-(2-CHLOROBENZYLOXY)PHENYL)-N-PHENYL-5-(PIPERIDIN-1-YL)-2,3-DIHYDRO-[1,2,4]TRIAZOLO[4,3-A][1,3,5]TRIAZIN-7-AMINE

phenyldiguanide

1-PHENYLBIGUANIDE

N-PHENYLIMINODICARBONIMIDIC-DIAMIDE

PHENYLBIGUANIDE

2-(N2-Phenylamidino)guanidine

1-phenyl-biguanid

n-phenyl-n’-guanylguanidine

p1426

phenyl-biguanid

Phenylbiguanide (Synonyms: N-Phenylbiguanide

Phenylbiguanide (N-Phenylbiguanide

Phenylbiguanide&gt

N-Phenylbiguanide

Imidodicarbonimidic diamide, N-phenyl-

5-hydroxytryptamine Receptor,Phenylbiguanide,inhibit,Serotonin Receptor,Inhibitor,5-HT Receptor

1-Phenylbiguanide, 5-HT3 receptor agonist

Phenylbiguanide, 10 mM in DMSO

102-02-3

C8H11N5

C6H5NHCNHNHCNH

C6H5NHCNHNHCNHNH2

Building Blocks

Guanidines

Organic Building Blocks

Nitrogen Compounds

AgonistsOrganic Building Blocks

Guanidines

Neurotransmitters

Nitrogen Compounds

Serotonergics