(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID

Product Name: (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
CAS No.: 100828-16-8
Chemical Name: (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
Synonyms: cppp;DL-CPP;3-2-Cpp;(RS)-CPP;(+/-)-CPP;(RS) CPP,(RS)CPP;(R,S)-CPP, NMDA antagonist;(+/-)-CPP POTENT AND SELECTIVE;4-(3-Phosphonopropyl)-2-piperazinecarboxylic acid;4-(3-phosphonopropyl)piperazine-2-carboxylic acid
CBNumber: CB5677423
Molecular Formula: C8H17N2O5P
Formula Weight: 252.2
MOL File: 100828-16-8.mol

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(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID Property

Boiling point:: 546.7±60.0 °C(Predicted)
Density: 1.408±0.06 g/cm3(Predicted)
storage temp.: Desiccate at RT
solubility: H₂O: 99.2 mg/mL
form: solid
pka: 1.89±0.20(Predicted)
color: white
Water Solubility: Soluble to 100 mM in water

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C104
Product name: (±)-CPP
Purity: solid
Packaging: 5mg
Price: $221
Updated: 2024/03/01

Sigma-Aldrich

Product number: C104
Product name: (±)-CPP
Purity: solid
Packaging: 25mg
Price: $757
Updated: 2024/03/01

Sigma-Aldrich

Product number: C104
Product name: (±)-CPP
Purity: solid
Packaging: 100mg
Price: $2560
Updated: 2024/03/01

Tocris

Product number: 0173
Product name: (RS)-CPP
Packaging: 50
Price: $818
Updated: 2021/12/16

Tocris

Product number: 0173
Product name: (RS)-CPP
Packaging: 10
Price: $195
Updated: 2021/12/16

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(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID Chemical Properties,Usage,Production

Uses

(+)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphoric Acid is a compound with NMDA antagonistic activity.

Synthesis Reference(s)

Tetrahedron Letters, 30, p. 5193, 1989 DOI: 10.1016/S0040-4039(01)93739-6

Biological Activity

Potent NMDA antagonist. See separate isomer (3-((R)-2-Carboxypiperazin-4-yl)-propyl-1-phosphonicacid ).

Biochem/physiol Actions

Potent and selective NMDA glutamate receptor antagonist; anticonvulsant.

storage

Room temperature (desiccate)

(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID Suppliers

China 20 Germany 2 India 1 Japan 1 South Korea 1 Switzerland 1 Ukraine 1 United Kingdom 2 United States 8 Global 37

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100828-16-8, (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACIDRelated Search:

2-Piperazinemethanol 4-METHYLPIPERAZINE-2-CARBOXYLIC ACID 3-((R)-2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID,R(-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID 3-Aminopropylphosphonic acid (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID 2,3-Diaminopropionic acid 2-Methylpiperazine PIPERAZINE-2-CARBOXYLIC ACID 2-Piperazinecarboxaldehyde (+/-)-3-(2-CARBOXY-PIPERAZIN-4-YL) PROPYL-1-PHOSPHONIC ACID-[PROPYL-1,2-3H]- azaleucine

(RS)-CPP

(RS)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID

(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID

DL-CPP

(+/-)-CPP

(+/-)-CPP POTENT AND SELECTIVE

2-Piperazinecarboxylic acid, 4-(3-phosphonopropyl)-

2-Piperazinecarboxylic acid, 4-(3-phosphonopropyl)-, (+-)-

3-2-Cpp

4-(3-Phosphonopropyl)-2-piperazinecarboxylic acid

Dl-3-(2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid

4-(3-phosphonopropyl)piperazine-2-carboxylic acid

(+)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphoric Acid

cppp

(+)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphoricAcid

(RS) CPP,(RS)CPP

(+/-)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid

(R,S)-CPP, NMDA antagonist

100828-16-8

Cell Signaling and Neuroscience

Cell Biology

BioChemical

Ligand-Gated Ion Channels

Ion Channels

Ionotropic Glutamate Receptor Modulators

Glutamate receptor

pharmaceutical intermediates