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ChemicalBook > CAS DataBase List > 4-BROMO-5-FLUORO-2-METHYLANILINE

4-BROMO-5-FLUORO-2-METHYLANILINE

Application
Product Name
4-BROMO-5-FLUORO-2-METHYLANILINE
CAS No.
52723-82-7
Chemical Name
4-BROMO-5-FLUORO-2-METHYLANILINE
Synonyms
4-Bromo-5-fluoro-o-toluidine;Methyl-4-bromo-5-fluoroaniline;2-Amino-4-fluoro-5-bromotoluene;2-AMINO-5-BROMO4-FLUORO TOLUENE;4-BROMO-5-FLUORO-2-METHYLANILINE;2-Methyl-4-bromo-5-fluoroaniline;4-bromo-5-fluoro-2-methylbenzenamine;Benzenamine, 4-bromo-5-fluoro-2-methyl-
CBNumber
CB5679856
Molecular Formula
C7H7BrFN
Formula Weight
204.04
MOL File
52723-82-7.mol
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4-BROMO-5-FLUORO-2-METHYLANILINE Property

Melting point:
77-80°C
Boiling point:
245℃
Density 
1.589
Flash point:
102℃
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
powder
pka
2.73±0.10(Predicted)
color 
Creamy beige
InChI
InChI=1S/C7H7BrFN/c1-4-2-5(8)6(9)3-7(4)10/h2-3H,10H2,1H3
InChIKey
BRAZFTXACIZDRP-UHFFFAOYSA-N
SMILES
C1(N)=CC(F)=C(Br)C=C1C
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Safety

HS Code 
2921410090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
B686448
Product name
4-Bromo-5-fluoro-2-methylaniline
Packaging
100mg
Price
$75
Updated
2021/12/16
Oakwood
Product number
013781
Product name
4-Bromo-5-fluoro-2-methylaniline
Purity
96%
Packaging
1g
Price
$15
Updated
2021/12/16
SynQuest Laboratories
Product number
3730-B-01
Product name
4-Bromo-5-fluoro-2-methylaniline?
Packaging
5G
Price
$42
Updated
2021/12/16
ChemScene
Product number
CS-W003221
Product name
4-Bromo-5-fluoro-2-methylaniline
Purity
99.47%
Packaging
10g
Price
$43
Updated
2021/12/16
Oakwood
Product number
013781
Product name
4-Bromo-5-fluoro-2-methylaniline
Purity
96%
Packaging
5g
Price
$45
Updated
2021/12/16
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4-BROMO-5-FLUORO-2-METHYLANILINE Chemical Properties,Usage,Production

Application

Polymers of aniline and aniline derivatives (such as 4-bromo-5-fluoro-2-methylaniline) can be used to manufacture thermoelectric materials. These materials are energy conversion materials that rely on temperature difference to drive the movement of charge carriers inside the material to achieve direct conversion of thermal energy and electrical energy. They are characterized by easy synthesis, tunable structure, electrical conductivity, good solubility, and low thermal conductivity.

Chemical Properties

Type of white solid

Synthesis

367-29-3

52723-82-7

General procedure for the synthesis of 4-bromo-5-fluoro-2-methylaniline from 5-fluoro-2-methylaniline: In a dry reaction flask, N-bromosuccinimide (NBS, 14.22 g, 80 mmol), 5-fluoro-2-methylaniline (10 g, 80 mmol), and N,N-dimethylformamide (DMF, 200 mL) were added in sequence. The reaction mixture was stirred at 25°C for 12 hours. Upon completion of the reaction, the mixture was slowly poured into ice water and a solid was precipitated. The solid was collected by filtration and washed with cold water to afford 4-bromo-5-fluoro-2-methylaniline (13 g, 71% yield) as a yellow solid. Product mass spectral data: LC-MS m/z 204 ([M + H]+), retention time 1.68 min.

References

[1] Patent: WO2016/203401, 2016, A1. Location in patent: Page/Page column 72
[2] Patent: WO2018/104766, 2018, A1. Location in patent: Page/Page column 72

4-BROMO-5-FLUORO-2-METHYLANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-BROMO-5-FLUORO-2-METHYLANILINE Suppliers

Carbosynth
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United Kingdom
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Fluorochem Ltd
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Fluorochem Ltd.
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View Lastest Price from 4-BROMO-5-FLUORO-2-METHYLANILINE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
4-BROMO-5-FLUORO-2-METHYLANILINE 52723-82-7
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-07
Henan Bao Enluo International TradeCo.,LTD
Product
4-BROMO-5-FLUORO-2-METHYLANILINE 52723-82-7
Price
US $50.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
10000MT
Release date
2023-08-15
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-BROMO-5-FLUORO-2-METHYLANILINE 52723-82-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10