ChemicalBook > CAS DataBase List > 4-Benzylpyridine

4-Benzylpyridine

Product Name
4-Benzylpyridine
CAS No.
2116-65-6
Chemical Name
4-Benzylpyridine
Synonyms
ba33216;Ba 33216;-BenzylPyridine;g-Benzylpyridine;4-benzyl-pyridin;4-BENZYLPYRIDINE;Pyridine, 4-benzyl-;4-Benzylpyridine,97%;gamma-Benzylpyridine;4-Benzylpyridine >
CBNumber
CB5682416
Molecular Formula
C12H11N
Formula Weight
169.22
MOL File
2116-65-6.mol
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4-Benzylpyridine Property

Melting point:
9-11 °C
Boiling point:
287 °C (lit.)
Density 
1.061 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.582(lit.)
Flash point:
239 °F
storage temp. 
Indoors
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Liquid
pka
5.75±0.10(Predicted)
color 
yellow
PH
8 (H2O, 20℃)
Water Solubility 
Soluble in ethanol, ethyl ether. Insoluble in water.
BRN 
115831
LogP
2.620
CAS DataBase Reference
2116-65-6(CAS DataBase Reference)
NIST Chemistry Reference
Pyridine, 4-(phenylmethyl)-(2116-65-6)
EPA Substance Registry System
Pyridine, 4-(phenylmethyl)- (2116-65-6)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
US2625000
TSCA 
Yes
HS Code 
29333999
Toxicity
LD50 ivn-mus: 25 mg/kg CSLNX* NX#12240orl-bwd LD50:18 mg/kg TXAPA9 21,315,72
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B30405
Product name
4-Benzylpyridine
Purity
98%
Packaging
5g
Price
$37.5
Updated
2025/07/31
TCI Chemical
Product number
B0437
Product name
4-Benzylpyridine
Purity
>98.0%(GC)
Packaging
25mL
Price
$18
Updated
2025/07/31
TRC
Product number
B289005
Product name
4-Benzylpyridine
Packaging
10g
Price
$80
Updated
2021/12/16
TRC
Product number
B289005
Product name
4-Benzylpyridine
Packaging
100g
Price
$225
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB45781
Product name
4-Benzylpyridine
Packaging
250g
Price
$50
Updated
2021/12/16
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4-Benzylpyridine Chemical Properties,Usage,Production

Chemical Properties

colorless or clear slightly yellow liquid. Boiling point 284-287°C, 180-181°C (4.13kPa). Relative density 1.062, refractive index 1.5785. soluble in ethanol, ether, insoluble in water.

Uses

4-Benzylpyridine is an important raw material and intermediate used in organic synthesis, pharmaceuticals, dyes and agrochemicals.It is the key raw material for the synthesis of Ifenprodil hemitartrate.

Preparation

4-Benzylpyridine is synthesized from benzyl chloride and pyridine.

Synthesis Reference(s)

The Journal of Organic Chemistry, 27, p. 1889, 1962 DOI: 10.1021/jo01052a509

Safety Profile

Poison by ingestion andintravenous routes. A flammable material. Incompatible with oxidizers. When heated to decomposition it emitstoxic fumes of NOx.

Purification Methods

Dry it with NaOH for several days, then distil it from CaO under reduced pressure, and redistil the middle fraction. [Beilstein 20/7 V 561.]

4-Benzylpyridine Preparation Products And Raw materials

Raw materials

Benzyl chloride

Preparation Products

4-(4-Nitrobenzyl)pyridine
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4-Benzylpyridine Suppliers

Americas 1 Belgium 3 China 64 Czech Republic 1 Europe 3 Germany 6 India 22 Italy 1 Japan 7 Russia 1 Slovakia 1 South Korea 1 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 11 United States 18 Global 144
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View Lastest Price from 4-Benzylpyridine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
4-Benzylpyridine 2116-65-6
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-04-30
Career Henan Chemical Co
Product
4-Benzylpyridine 2116-65-6
Price
US $1.00/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2019-12-25

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