ChemicalBook > CAS DataBase List > AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OH

AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OH

Product Name
AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OH
CAS No.
125441-00-1
Chemical Name
AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OH
Synonyms
AC-HIRUDIN (54-65) (SULFATED);ACETYL-HIRUDIN (54-65) (SULFATED);acetyl-[tyr(so3h)63]-hirudin fragment 54-65;Hirudin (54-65), acetylated, sulfated - 1 mg;N-acetyl-(tyr(so3H)63)-hirudin *fragment 54-65;N-ACETYL-HIRUDIN AC-[TYR(SO3H)63]-FRAGMENT 54-65;AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN;AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OH;ACETYL-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR[SO3H]-LEU-GLN;Acetyl-Hirudin (54-65) (sulfated) Ac-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln-OH
CBNumber
CB5689460
Molecular Formula
C68H95N13O29S
Formula Weight
1590.62
MOL File
125441-00-1.mol
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AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OH Property

Density 
1.416±0.06 g/cm3(Predicted)
storage temp. 
−20°C
pka
-4.17±0.18(Predicted)
Sequence
Ac-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-{Try(SO3H)}-Leu-Gln
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FA110094
Product name
Acetyl-Hirudin (54-65) (sulfated) Ac-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln-OH
Packaging
50ug
Price
$99
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA110094
Product name
Acetyl-Hirudin (54-65) (sulfated) Ac-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln-OH
Packaging
100ug
Price
$172
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA110094
Product name
Acetyl-Hirudin (54-65) (sulfated) Ac-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln-OH
Packaging
250ug
Price
$342.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA110094
Product name
Acetyl-Hirudin (54-65) (sulfated) Ac-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln-OH
Packaging
500ug
Price
$595
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0004021
Product name
ACETYL-[TYR(SO3H)63]-HIRUDIN FRAGMENT 54-65
Purity
95.00%
Packaging
1MG
Price
$970.2
Updated
2021/12/16
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AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OH Chemical Properties,Usage,Production

Uses

Acetyl-Hirudin (54-65) (sulfated) is a acetyl-fragment of Hirudin which binds directly to thrombin-rHCII(L444R) and disrupts interactions between the N-terminal acidic domain of rHCII and anion-binding exosite I of thrombin that serves to stabilize the complex[1].

References

[1] J H Han, et al. Heparin facilitates dissociation of complexes between thrombin and a reactive site mutant (L444R) of heparin cofactor II. J Biol Chem. 1997 Mar 28;272(13):8243-9. DOI:10.1074/jbc.272.13.8243

AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OH Suppliers

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125441-00-1, AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OHRelated Search:


  • AC-HIRUDIN (54-65) (SULFATED)
  • AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN
  • AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OH
  • N-acetyl-(tyr(so3H)63)-hirudin *fragment 54-65
  • acetyl-[tyr(so3h)63]-hirudin fragment 54-65
  • N-ACETYL-HIRUDIN AC-[TYR(SO3H)63]-FRAGMENT 54-65
  • ACETYL-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR[SO3H]-LEU-GLN
  • ACETYL-HIRUDIN (54-65) (SULFATED)
  • Acetyl-Hirudin (54-65) (sulfated) Ac-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln-OH
  • L-Glutamine,N2-[N-[N-[N-[N-[1-[N-[N-[N-[N-[N-(N-acetylglycyl)-L-α-aspartyl]-L-phenylalanyl]-L-α-glutamyl]-L-α-glutamyl]-L-isoleucyl]-L-prolyl]-L-α-glutamyl]-L-α-glutamyl]-O-sulfo-L-tyrosyl]-L-leucyl]-
  • L-Glutamine, N-acetylglycyl-L-α-aspartyl-L-phenylalanyl-L-α-glutamyl-L-α-glutamyl-L-isoleucyl-L-prolyl-L-α-glutamyl-L-α-glutamyl-O-sulfo-L-tyrosyl-L-leucyl- (9CI)
  • Hirudin (54-65), acetylated, sulfated - 1 mg
  • 125441-00-1
  • C68H95N13O29S
  • Biochemicals and Reagents
  • Amino Acids and Peptides
  • BioChemical
  • Miscellaneous Peptides
  • Hirudin Fragments
  • Peptides
  • Hirudin Fragments
  • Miscellaneous Peptides
  • Peptides for Cell Biology