ChemicalBook > CAS DataBase List > AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OH
AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OH
- Product Name
- AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OH
- CAS No.
- 125441-00-1
- Chemical Name
- AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OH
- Synonyms
- AC-HIRUDIN (54-65) (SULFATED);ACETYL-HIRUDIN (54-65) (SULFATED);acetyl-[tyr(so3h)63]-hirudin fragment 54-65;Hirudin (54-65), acetylated, sulfated - 1 mg;N-acetyl-(tyr(so3H)63)-hirudin *fragment 54-65;N-ACETYL-HIRUDIN AC-[TYR(SO3H)63]-FRAGMENT 54-65;AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN;AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OH;ACETYL-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR[SO3H]-LEU-GLN;Acetyl-Hirudin (54-65) (sulfated) Ac-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln-OH
- CBNumber
- CB5689460
- Molecular Formula
- C68H95N13O29S
- Formula Weight
- 1590.62
- MOL File
- 125441-00-1.mol
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AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OH Property
- Density
- 1.416±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- pka
- -4.17±0.18(Predicted)
- Sequence
- Ac-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-{Try(SO3H)}-Leu-Gln
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Biosynth Carbosynth
- Product number
- FA110094
- Product name
- Acetyl-Hirudin (54-65) (sulfated) Ac-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln-OH
- Packaging
- 50ug
- Price
- $99
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FA110094
- Product name
- Acetyl-Hirudin (54-65) (sulfated) Ac-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln-OH
- Packaging
- 100ug
- Price
- $172
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FA110094
- Product name
- Acetyl-Hirudin (54-65) (sulfated) Ac-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln-OH
- Packaging
- 250ug
- Price
- $342.5
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FA110094
- Product name
- Acetyl-Hirudin (54-65) (sulfated) Ac-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln-OH
- Packaging
- 500ug
- Price
- $595
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- PEP0004021
- Product name
- ACETYL-[TYR(SO3H)63]-HIRUDIN FRAGMENT 54-65
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $970.2
- Updated
- 2021/12/16
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AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OH Chemical Properties,Usage,Production
Uses
Acetyl-Hirudin (54-65) (sulfated) is a acetyl-fragment of Hirudin which binds directly to thrombin-rHCII(L444R) and disrupts interactions between the N-terminal acidic domain of rHCII and anion-binding exosite I of thrombin that serves to stabilize the complex[1].
References
[1] J H Han, et al. Heparin facilitates dissociation of complexes between thrombin and a reactive site mutant (L444R) of heparin cofactor II. J Biol Chem. 1997 Mar 28;272(13):8243-9. DOI:10.1074/jbc.272.13.8243
AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OH Preparation Products And Raw materials
Raw materials
Preparation Products
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125441-00-1, AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OHRelated Search:
HIRUDIN (54-65) (DESULFATED)
D-AMPHETAMINE SULFATE
Glycyl-L-glutamine monohydrate
GLYCYL-L-GLUTAMINE MONOHYDRATE
L-LEUCYL-L-ALANINE
(S)-Propane-1,2-diamine sulfate
L-Alanyl-L-Glutamine
HIRUDIN
AC-ALA-GLN-OH
H-ALA-ALA-ALA-TYR-ALA-ALA-OH
HIRUDIN (54-65) (SULFATED)
H-TYR-GLY-GLY-OH H2O
HIRUDIN (55-65) (SULFATED)
SULFURIC ACID:TRIETHYLAMINE 2M:2M
N-ACETYL-L-GLYCYL-L-GLUTAMINE
H-ALA-ALA-TYR-ALA-ALA-OH
AC-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR(SO3H)-LEU-GLN-OH
ACETYL-HIRUDIN (55-65) (SULFATED)