beta-Cyclodextrin methyl ethers
- Product Name
- beta-Cyclodextrin methyl ethers
- CAS No.
- 128446-36-6
- Chemical Name
- beta-Cyclodextrin methyl ethers
- Synonyms
- Methyl-β-cyclodextrin;MBC;METHYL-BETA-CYCLODEXTRIN;Me-β-CD;Methyl-beta-cyclodextrine;MBCD;MEBCD;Me-β-CD;BETA-CYD;RM-β-CD-o
- CBNumber
- CB5696215
- Molecular Formula
- C54H94O35
- Formula Weight
- 1303.3
- MOL File
- 128446-36-6.mol
beta-Cyclodextrin methyl ethers Property
- Melting point:
- 180-182 °C(lit.)
- alpha
- +159°(25℃, c=1, H2O)
- Flash point:
- 187 °C
- storage temp.
- room temp
- solubility
- H2O: soluble50mg/mL
- form
- powder
- color
- White to off-white
- optical activity
- [α]25/D +159°, c = 1 in H2O
- Water Solubility
- Soluble in water
- InChIKey
- YZOUYRAONFXZSI-SBHWVFSVSA-N
- LogP
- -2.566 (est)
- EPA Substance Registry System
- .beta.-Cyclodextrin, methyl ethers (128446-36-6)
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- TSCA
- Yes
- HS Code
- 35051000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
H361Suspected of damaging fertility or the unborn child
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P272Contaminated work clothing should not be allowed out of the workplace.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P308+P313IF exposed or concerned: Get medical advice/attention.
P363Wash contaminated clothing before reuse.
P403Store in a well-ventilated place.
N-Bromosuccinimide Price
- Product number
- 332615
- Product name
- Methyl-β-cyclodextrin
- Purity
- average Mn 1310
- Packaging
- 5g
- Price
- $52.5
- Updated
- 2024/03/01
- Product number
- 332615
- Product name
- Methyl-β-cyclodextrin
- Purity
- average Mn 1310
- Packaging
- 25g
- Price
- $171
- Updated
- 2024/03/01
- Product number
- M1356
- Product name
- Methyl-β-cyclodextrin (mixture of several Methylated)
- Packaging
- 25g
- Price
- $109
- Updated
- 2024/03/01
- Product number
- M1356
- Product name
- Methyl-β-cyclodextrin (mixture of several Methylated)
- Packaging
- 250g
- Price
- $544
- Updated
- 2024/03/01
- Product number
- J66847
- Product name
- Methyl-beta-cyclodextrin
- Packaging
- 5g
- Price
- $47.5
- Updated
- 2024/03/01
beta-Cyclodextrin methyl ethers Chemical Properties,Usage,Production
Description
Methyl-β-cyclodextrin is a randomly methylated form of the cyclic oligosaccharide β-cyclodextrin . Methyl-β-cyclodextrin contains seven D-(+)-glucopyranose units that contain randomized hydrogen or methyl groups. Methyl-β-cyclodextrin has been used to improve the aqueous solubility of various compounds and to extract cholesterol from lipid membranes. Methyl-β-cyclodextrin (5 mM) reduces α-synuclein levels in the membrane and detergent-insoluble fractions from B103 neuroblastoma cells transfected with human α-synuclein. It also reduces α-synuclein levels in mouse brain in a transgenic model of α-synucleinopathy.
Chemical Properties
White powder
Uses
substrate for laminarinase and other glucanases
Uses
Cavity size is the major determinant as to which cyclodextrin is used in complexation. The cavity diameter of β-cyclodextrins or β-glucopyranose unit compounds is well-suited for use with molecules the size of hormones, vitamins and many compounds frequently used in tissue and cell culture applications. For this reason, β-cyclodextrin is most commonly used as a complexing agent. It is used to increase the solubility of non-polar substances such as fatty acids, lipids, vitamins and cholesterol for use in cell culture applications. Methyl-β-cyclodextrin is used to remove cholesterol from cultured cells and is employed to remove lipid rafts.
Uses
Methyl-β-cyclodextrin is a cholesterol-removing agent mainly used for lipid raft disruption. It may also be used for detergent removal from protein-lipid-detergent ternary mixture to produce 2D membrane protein crystals due to its high solubility and affinity for detergents generally used in membrane protein chemistry.
General Description
Methyl-β-cyclodextrin is a small cyclic heptasaccharide.
Biochem/physiol Actions
Methyl-β-cyclodextrin participates in increasing the permeability of cells. It also plays a role in depolymerizing the actin cytoskeleton in cells. Methyl-β-cyclodextrin is involved in attracting cholesterol from the plasma. It participates in activating extracellular receptor kinase in certain cells.
beta-Cyclodextrin methyl ethers Preparation Products And Raw materials
Raw materials
Preparation Products
beta-Cyclodextrin methyl ethers Suppliers
- Tel
- 44-20819178-90 02081917890
- Fax
- (0)2080432064
- info@novachemistry.com
- Country
- United Kingdom
- ProdList
- 4381
- Advantage
- 58
View Lastest Price from beta-Cyclodextrin methyl ethers manufacturers
- Product
- beta-Cyclodextrin methyl ethers 128446-36-6
- Price
- US $10.00-7.00/kg
- Min. Order
- 1kg
- Purity
- 99.99%
- Supply Ability
- 10 tons
- Release date
- 2024-06-14
- Product
- beta-Cyclodextrin methyl ethers 128446-36-6
- Price
- US $40.00-40.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-09-18
- Product
- beta-Cyclodextrin methyl ethers 128446-36-6
- Price
- US $10.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 99.5%
- Supply Ability
- 100 TON
- Release date
- 2020-11-20