THIOPHENE-2-THIOCARBOXAMIDE

Product Name: THIOPHENE-2-THIOCARBOXAMIDE
CAS No.: 20300-02-1
Chemical Name: THIOPHENE-2-THIOCARBOXAMIDE
Synonyms: THIOPHENE-2-CARBOTHIOAMIDE;THIOPHENE-2-THIOAMIDE;OTAVA-BB BB7020331311;2-Thiocarbamoylthiophene;2-Thienylthiocarboxamide;2-Thiophenecarbothioamide;Thiophen-2-carbothioamide;Thiophen-2-thiocarboxamid;2-Thiophenethiocarboxamide;THIOPHENE-2-THIOCARBOXAMIDE
CBNumber: CB5697863
Molecular Formula: C5H5NS2
Formula Weight: 143.23
MOL File: 20300-02-1.mol

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THIOPHENE-2-THIOCARBOXAMIDE Property

Melting point:: 106 °C
Boiling point:: 260℃
Density: 1.357
Flash point:: 111℃
storage temp.: 2-8°C(protect from light)
form: powder to crystal
pka: 12.56±0.29(Predicted)
color: White to Yellow to Green
Water Solubility: Insoluble in water.
BRN: 110159
CAS DataBase Reference: 20300-02-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 25-43
Safety Statements: 22-36/37/39-45-36/37
RIDADR: 2811
Hazard Note: Irritant
HazardClass: 6.1
PackingGroup: III
HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P309IF exposed or if you feel unwell:

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS014286
Product name: Thiophene-2-carbothioamide
Purity: Aldrich<SUP>CPR</SUP>
Packaging: 250 mg
Price: $73.1
Updated: 2025/07/31

TCI Chemical

Product number: T3604
Product name: Thiophene-2-carbothioamide
Purity: >98.0%(HPLC)
Packaging: 5g
Price: $407
Updated: 2025/07/31

TCI Chemical

Product number: T3604
Product name: Thiophene-2-carbothioamide
Purity: >98.0%(HPLC)
Packaging: 25g
Price: $1286
Updated: 2025/07/31

TRC

Product number: T430110
Product name: Thiophene-2-thiocarboxamide
Packaging: 10mg
Price: $45
Updated: 2021/12/16

TRC

Product number: T430110
Product name: Thiophene-2-thiocarboxamide
Packaging: 50mg
Price: $60
Updated: 2021/12/16

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THIOPHENE-2-THIOCARBOXAMIDE Chemical Properties,Usage,Production

Uses

Thiophene-2-thiocarboxamide is used as a pharmaceutical intermediate.

Synthesis

5813-89-8

20300-02-1

General procedure for the synthesis of thiophene-2-thioformamide from 2-thiophenecarboxamide: 2-thiophenecarboxamide (1 g, 7.86 mmol) was dissolved in dry 1,2-dimethoxyethane (30 mL). Lawesson's reagent (1.6 g, 3.9 mmol) was added and the reaction was protected under nitrogen. The reaction mixture was stirred at room temperature for 12 hours and then filtered. Subsequently, the solvent was removed by distillation under reduced pressure and the residue was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate = 10:1 to 2:1) to afford thiophene-2-thiocarboxamide (1.0 g, 88.8% yield, white solid). Thiophene-2-carbothioamide can be used directly in the subsequent reaction without further purification.

References

[1] Patent: EP2708534, 2014, A1. Location in patent: Paragraph 0055
[2] ACS Medicinal Chemistry Letters, 2013, vol. 4, # 10, p. 904 - 908
[3] Journal of Medicinal Chemistry, 2017, vol. 60, # 17, p. 7512 - 7523
[4] Chemistry - A European Journal, 2013, vol. 19, # 29, p. 9655 - 9662
[5] Journal of Chemical Research, 2010, # 3, p. 151 - 153

THIOPHENE-2-THIOCARBOXAMIDE Preparation Products And Raw materials

Raw materials

N-Methyl-2-pyrrolidone 2-Thiophenecarboxaldehyde N,N-Dimethylformamide Hydroxylamine hydrochloride Sodium hydrosulfide Magnesium chloride hexahydrate

Preparation Products

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THIOPHENE-2-THIOCARBOXAMIDE Suppliers

Belgium 1 China 100 France 1 Germany 3 India 6 Japan 1 Switzerland 1 Ukraine 2 United Kingdom 7 United States 17 Global 139

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
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Alfa Aesar

Tel: 400-6106006
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Email: saleschina@alfa-asia.com
Country: China
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Energy Chemical

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Email: sales8178@energy-chemical.com
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Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
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Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

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Syntechem Co.,Ltd

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Hangzhou Yuhao Chemical Technology Co., Ltd

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T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
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Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

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View Lastest Price from THIOPHENE-2-THIOCARBOXAMIDE manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: THIOPHENE-2-THIOCARBOXAMIDE 20300-02-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-29

Shaanxi Dideu Medichem Co. Ltd

Product: Thiophene-2-carbothioic acid amide 20300-02-1
Price: US $0.01-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 tons
Release date: 2020-04-22

Shanghai Rlavie Technology Co ltd

Product: Thiophene-2-thiocarboxamide 20300-02-1
Price: US $0.00/KG
Min. Order: 1g
Purity: 98%minHPLC
Supply Ability: 50kgs/month
Release date: 2021-11-16

20300-02-1, THIOPHENE-2-THIOCARBOXAMIDERelated Search:

THIOPHENE-3-THIOCARBOXAMIDE THIFLUZAMIDE 3-Thiopheneboronic acid 3-THIOPHENECARBOXYLIC ACID HYDRAZIDE 5,5-Dimethyl-2-(thiophen-2-yl)-1,3,2-dioxaborinane Thiophene-2,3-dicarboxylicacid Dimethyl thiophene-2,3-dicarboxylate Thiazolyl Blue Pseudothiohydantoin 2,5-Bis-Thiopheneboronic acid pinacol ester Thiophene-2,3-dicarboxylic acid THIENO[3,2-B]PYRIDINE Ethylthiophene-2-carboximidoatehydrochloride ETHYL THIOPHENE-2-GLYOXYLATE 2(5 H)-THIOPHENONE 2-Thiophenesulfonic acid (2-methylphenyl)(thien-2-yl)methanone 3-AMinothiophene Oxalate

OTAVA-BB BB7020331311

THIOPHENE-2-THIOAMIDE

THIOPHENE-2-THIOCARBOXAMIDE

THIOPHENE-2-CARBOTHIOAMIDE

THIOPHENE-2-CARBOTHIOIC ACID AMIDE

Thiophene-2-carbothioamide, 95+%

Thiophene-2-carbothioic acid amide, 2-Carbamothioylthiophene

2-(Aminothiocarbonyl)thiophene

2-Thienylthiocarboxamide

2-Thiocarbamoylthiophene

2-Thiophenecarbothioamide

2-Thiophenethiocarboxamide

Thiophen-2-carbothioamide

thiohypofluorous acid (4-oxo-3,4-dihydro-2H-1-benzopyran-6-yl) ester

Thiophen-2-thiocarboxamid

Thiophene-2-thiocarboxamide-97%

20300-02-1