ChemicalBook > CAS DataBase List > Hydroxylamine-O-sulfonic acid

Hydroxylamine-O-sulfonic acid

Product Name
Hydroxylamine-O-sulfonic acid
CAS No.
2950-43-8
Chemical Name
Hydroxylamine-O-sulfonic acid
Synonyms
HOSA;HYDROXYLAMINE-O-SULPHONIC ACID;HOS;amino hydrogen sulfate;HydroxylaMine-0-sulfonic acid;haos;Amino hydrogen sulphate;HYDROXYLAMINESULFONIC ACID;o-hydroxylammoniumsulfonate;TBX5
CBNumber
CB5702901
Molecular Formula
H3NO4S
Formula Weight
113.09
MOL File
2950-43-8.mol
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Hydroxylamine-O-sulfonic acid Property

Melting point:
210 °C (dec.)(lit.)
Boiling point:
39 °C(Press: 0.4 Torr)
Density 
2.2 g/cm3 (20℃)
vapor pressure 
0-53.329Pa at 25-39℃
storage temp. 
2-8°C
solubility 
675g/l (slow decomposition)
pka
-6.47±0.18(Predicted)
form 
Crystalline Powder
color 
White
PH
0.8 (100g/l, H2O, 20℃)
Water Solubility 
soluble
Sensitive 
Hygroscopic
BRN 
956566
InChIKey
DQPBABKTKYNPMH-UHFFFAOYSA-N
CAS DataBase Reference
2950-43-8(CAS DataBase Reference)
EPA Substance Registry System
Hydroxylamine-O-sulfonic acid (2950-43-8)
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Safety

Hazard Codes 
C,N
Risk Statements 
34-50-43-40-22
Safety Statements 
26-36/37/39-45-61-28A-27-22
RIDADR 
UN 3260 8/PG 3
WGK Germany 
3
RTECS 
NC5427000
F 
10-21
Hazard Note 
Irritant
TSCA 
Y
HazardClass 
8
PackingGroup 
III
HS Code 
28111980
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
HPA072204
Product name
Anti-FBXW11 antibody produced in rabbit
Purity
Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody
Packaging
100μL
Price
$580
Updated
2024/03/01
Sigma-Aldrich
Product number
HPA062578
Product name
Anti-FBXW11 antibody produced in rabbit
Purity
Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody
Packaging
100μL
Price
$580
Updated
2024/03/01
Sigma-Aldrich
Product number
213136
Product name
Hydroxylamine-O-sulfonic acid
Purity
97%
Packaging
25g
Price
$147
Updated
2024/03/01
Sigma-Aldrich
Product number
HPA072204
Product name
Anti-FBXW11 antibody produced in rabbit
Purity
Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody
Packaging
25μL
Price
$282
Updated
2023/06/20
TCI Chemical
Product number
H0530
Product name
Hydroxylamine-O-sulfonic Acid
Purity
>90.0%(T)
Packaging
25g
Price
$93
Updated
2024/03/01
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Hydroxylamine-O-sulfonic acid Chemical Properties,Usage,Production

Chemical Properties

white to slightly beige crystalline powder

Uses

Hydroxylamine-O-sulfonic acid is used in the synthesis of quinolones for the benzodiazepine site of GABAA receptors. It is also used as a polymerization catalyst and an amination reagent. It is involved in the preparation of diazene by reacting with an alkali. It is also used in the inhibition of polychlorinated dibenzo-p-dioxins (PCDD) as well as (polychlorinated biphenyl) PCB formation in co-combustion.

Uses

Hydroxylamine-O-sulfonic acid (HOSA) may be used to synthesize (Z)-1H-purin-6(7H)-ylideneaminooxysulfonic acid.
HOSA may be used as an aminating reagent in the synthesis of:

  • 1-aminotetrazoles and 2-aminotetrazoles
  • N-aminopiperidine (NAPP)
  • 1H,1′ H-2,2′-biimidazole-1,1′-diamine

General Description

Hydroxylamine-O-sulfonic acid is a versatile synthetic reagent. It is widely employed as a nucleophile and as an electrophile in various organic syntheses. It can be synthesized by reacting hydroxylamine sulfate with 30% fuming H2SO4.

Purification Methods

Stir the solid vigorously with anhydrous Et2O and filter it off using large volumes of dry Et2O. Drain dry at the pump for 5minutes and then for 12-14hours in a vacuum. Store it in a vacuum desiccator over conc H2SO4. Determine the purity by oxidation of iodide to I2. It must be stored in a dry atmosphere at 0-4o. It decomposes slowly in H2O at 25o and more rapidly above this temperature. [Matsuguma & Andrieth Inorg Synth V 122 1957.]

Hydroxylamine-O-sulfonic acid Preparation Products And Raw materials

Raw materials

Preparation Products

3-(3-Nitrophenyl)propionic acid 1-ISOPROPYL-5-HYDROXYPYRAZOL Dimethylglyoxime Pyrazolo[1,5-a]pyridine-3-carboxylic acid
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View Lastest Price from Hydroxylamine-O-sulfonic acid manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Product
Hydroxylamine-O-sulfonic acid 2950-43-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-09-06
Zibo Hangyu Biotechnology Development Co., Ltd
Product
Hydroxylamine-O-sulfonic acid 2950-43-8
Price
US $70.00-700.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-01
Shanghai Bojing Chemical Co.,Ltd.
Product
Hydroxylamine-O-sulfonic acid 2950-43-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5MT
Release date
2023-12-14

2950-43-8, Hydroxylamine-O-sulfonic acidRelated Search:

4-Nitrotoluene-2-sulfonic Acid Aniline-2-sulfonic acid 4-NITRO-2-SULFOANILINE 2,7-Naphthalenedisulfonic acid disodium salt Ethyl 2-(Chlorosulfonyl)acetate N-Phenylhydroxylamine Folic acid Glycine N,N-Diethylhydroxylamine METARAMINOL Hydroxylamine sulfate Hydroxylamine hydrochloride HYDROXYLAMINE Heptafluorobutyric acid HYDROXYLAMINE NITRATE SINIGRIN SINIGRIN MONOHYDRATE sodium benzaldehyde-o-sulfonate

  • amidoperoxymonosulfuricacid
  • amidosulfonicperacid
  • aminomonopersulfuricacid
  • haos
  • o-hydroxylammoniumsulfonate
  • permonosulfamicacid
  • sulfoperamidicacid
  • HOS
  • HOSA
  • amino hydrogen sulfate
  • HYDROXYLAMINE-D-SULFONIC ACID
  • (Sulfooxy)amine
  • O-Sulfohydroxylamine
  • Amino hydrogen sulphate
  • (Aminooxy)(hydroxy)sulphane dioxide
  • Hydroxylamine-O-sulfonic acid,90%
  • Hydroxylamine-O-sulfonic acid,97%
  • Hydroxylamine-O-sulf
  • HYDROXYLAMINE-O-SULFONIC ACID, 99.999%
  • HYDROXYLAMINE-O-SULFONIC ACID, TECH., 90 %
  • Hydrozylamine-0-Sulfonic Acid
  • Hydraxylamine-O-SulphonicAcid96-97%
  • amine-O-suL
  • HYDROXYLAMINE-O-SULFONIC ACID
  • HYDROXYLAMINE-O-SULPHONIC ACID
  • HYDROXYLAMINESULFONIC ACID
  • HYDROXYLAMMONIUM-O-SULFONIC ACID
  • Anti-tbx5a antibody produced in rabbit
  • tbx5.1
  • tbx5a
  • zTbx5
  • Anti-FBXW11 antibody produced in rabbit
  • Fbw11
  • FBW1B
  • FBXW1B
  • Monoclonal Anti-TBX5 antibody produced in mouse
  • TBX5
  • Hydroxylamine-O-sulfonic acid 97%
  • HydroxylaMine-0-sulfonic acid
  • Sulfuricacid, Monoazanyl ester
  • HydroxylaMine-O-sulfonic acid (HOSA)
  • Hydroxylamine-O-sulfonicAcid&gt
  • Hydroxylamine-O-sulfonic acid (6CI, 7CI, 8CI, 9CI)
  • hyroxyl amine -o-sulfonic acid
  • 2950-43-8
  • H2NOSO3H
  • NH2OSO3H
  • H3NSO4
  • H3NO4S
  • Hydroxylamines (O-Substituted)
  • Amination
  • Hydroxylamines
  • Building Blocks
  • Organic Building Blocks
  • Sulfonic/Sulfinic Acids
  • Sulfur Compounds
  • Building Blocks
  • Chemical Synthesis