20-HETE
- Product Name
- 20-HETE
- CAS No.
- 79551-86-3
- Chemical Name
- 20-HETE
- Synonyms
- 20-HETE;20-HYDROXYARACHIDONIC ACID;20-Hydroxyarachlidonic acid;omega-Hydroxyarachidonic acid;20-HETE Lipid Maps MS Standard;20-Hydroxyeicosatetraenoic acid;20-HETE, 20-Hydroxyarachidonic acid;20-hydroxy-5,8,11,14-eicosatetraenoic acid;20-Hydroxyeicosa-5Z,8Z,11Z,14Z-tetraenoic acid;20-HYDROXY-(5Z,8Z,11Z,14Z)-EICOSATETRAENOIC ACID
- CBNumber
- CB5710278
- Molecular Formula
- C20H32O3
- Formula Weight
- 320.47
- MOL File
- 79551-86-3.mol
20-HETE Property
- Boiling point:
- 482.0±33.0 °C(Predicted)
- Density
- 0.985±0.06 g/cm3(Predicted)
- Flash point:
- 14℃
- storage temp.
- -20°C
- solubility
- 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
- pka
- 4.75±0.10(Predicted)
- form
- Powder
Safety
- Hazard Codes
- F,Xi
- Risk Statements
- 11-36/37/38
- Safety Statements
- 16-26-36
- RIDADR
- UN 1170 3/PG 2
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- H3023
- Product name
- 20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid
- Purity
- ~100?μg/mL in ethanol, ≥90% (HPLC)
- Packaging
- 10μg
- Price
- $268
- Updated
- 2024/03/01
- Product number
- H3023
- Product name
- 20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid
- Purity
- ~100?μg/mL in ethanol, ≥90% (HPLC)
- Packaging
- 50μg
- Price
- $1060
- Updated
- 2024/03/01
- Product number
- 90030
- Product name
- 20-HETE
- Purity
- ≥98%
- Packaging
- 25μg
- Price
- $162
- Updated
- 2024/03/01
- Product number
- 10007269
- Product name
- 20-HETE MaxSpec? Standard
- Purity
- ≥95%
- Packaging
- 10μg
- Price
- $224
- Updated
- 2024/03/01
- Product number
- 90030
- Product name
- 20-HETE
- Purity
- ≥98%
- Packaging
- 50μg
- Price
- $306
- Updated
- 2024/03/01
20-HETE Chemical Properties,Usage,Production
Uses
20-HETE is a cytochrome P450 (CYP450) metabolite that may play an autacoid role in cerebral and renal vasculature.
Definition
ChEBI: A HETE that consists of arachidonic acid bearing a hydroxy substituent at position 20.
Biochem/physiol Actions
20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid (20-HETE) is an arachidonic acid metabolite via cytochrome P4504A, that is an activator of the Ras/MAP (microtubule-associated protein) pathway. 20-HETE acid is a predominant arachidonic acid present in the kidney. It is involved in the regulation of sodium, potassium and chloride transport in the renal tubules. 20-HETE is often excreted in urine in the form of glucuronide conjugate and sometimes as free acids. Increased urine 20-HETE is observed during pregnancy in rats.