6-CHLORO-4-HYDROXYQUINOLINE

Product Name: 6-CHLORO-4-HYDROXYQUINOLINE
CAS No.: 23432-43-1
Chemical Name: 6-CHLORO-4-HYDROXYQUINOLINE
Synonyms: 6-CHLORO-4-QUINOLINOL;6-CHLOROQUINOLIN-4-OL;4-Quinolinol, 6-chloro-;6-CHLOROQUINOLIN-4(1H)-ONE;6-CHLORO-4-HYDROXYQUINOLINE;4-HYDROXY-6-CHLOROQUINOLINE
CBNumber: CB5711644
Molecular Formula: C9H6ClNO
Formula Weight: 179.6
MOL File: 23432-43-1.mol

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6-CHLORO-4-HYDROXYQUINOLINE Property

Melting point:: 269°C(lit.)
Boiling point:: 348.5±22.0 °C(Predicted)
Density: 1.412±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
form: powder to crystal
pka: 3.89±0.40(Predicted)
color: White to Light gray to Light yellow
InChIKey: XXGUQCVVGPZTPF-UHFFFAOYSA-N

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Safety

Hazard Codes: E,Xn
Risk Statements: 22
HS Code: 2933499090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: OTV000284
Product name: 6-Chloro-4-quinolinol
Purity: AldrichCPR
Packaging: 1G
Price: $216
Updated: 2025/07/31

TCI Chemical

Product number: C3312
Product name: 6-Chloro-4-quinolinol
Purity: >98.0%(GC)
Packaging: 1g
Price: $37
Updated: 2025/07/31

TCI Chemical

Product number: C3312
Product name: 6-Chloro-4-quinolinol
Purity: >98.0%(GC)
Packaging: 5g
Price: $113
Updated: 2025/07/31

TRC

Product number: B419428
Product name: 6-Chloroquinolin-4-ol
Packaging: 100mg
Price: $60
Updated: 2021/12/16

Chem-Impex

Product number: 44898
Product name: 6-Chloro-4-quinolinol,≥98%(GC)
Purity: ≥98%(GC)
Packaging: 1G
Price: $51.39
Updated: 2021/12/16

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6-CHLORO-4-HYDROXYQUINOLINE Chemical Properties,Usage,Production

Chemical Properties

off White powder

Synthesis

21617-20-9

23432-43-1

General procedure for the synthesis of 4-hydroxy-6-chloroquinoline from 6-chloro-4-oxo-2,3-dihydroquinoline: 6-chloro-4-oxo-2,3-dihydroquinoline (0.01 mol) was placed in a 25 mL reaction flask, and 15 mL of acetonitrile and acetic acid (0.01 mol) were added and stirred for 20 min. Subsequently, hydrogen peroxide (0.03 mol) was added slowly and the reaction was stirred at 65 °C. The progress of the reaction was monitored by thin layer chromatography (TLC) and the reaction was terminated after 7 hours. After the reaction solution was cooled to room temperature, it was poured into 50 mL of water, stirred and filtered to obtain the crude product of 4-hydroxy-6-chloroquinoline. The crude product was purified by silica gel column chromatography (silica gel 100-200 mesh, eluent was petroleum ether:ethyl acetate=1:4), and the target component was collected and concentrated to obtain the pure product. The product yield was 88% and purity was 96%.

References

[1] Patent: CN108794396, 2018, A. Location in patent: Paragraph 0017
[2] Journal of the American Chemical Society, 1949, vol. 71, p. 1906,1910

6-CHLORO-4-HYDROXYQUINOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-CHLORO-4-HYDROXYQUINOLINE Suppliers

Americas 1 Canada 1 China 99 Europe 3 Germany 2 India 2 Japan 2 United Kingdom 4 United States 16 Global 130

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
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Energy Chemical

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Wuhan Chemwish Technology Co., Ltd

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Beijing Ouhe Technology Co., Ltd

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Shanghai Longsheng chemical Co.,Ltd.

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Chengdu Forest Science and Technology Development Co., Ltd.

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TOKYO CHEMICAL INDUSTRY CO., LTD.

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View Lastest Price from 6-CHLORO-4-HYDROXYQUINOLINE manufacturers

Career Henan Chemical Co

Product: 6-CHLORO-4-HYDROXYQUINOLINE 23432-43-1
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 10000KGS
Release date: 2020-01-11

23432-43-1, 6-CHLORO-4-HYDROXYQUINOLINERelated Search:

6-CHLORO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID 6-CHLORO-4-HYDROXY-2-METHYLQUINOLINE 6-CHLORO-4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINE 6,8-DICHLORO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL 4-HYDROXY-6,8-DICHLOROQUINOLINE 6-CHLORO-4-HYDROXYQUINOLINE 6-CHLORO-4-HYDROXY-8-METHYLQUINOLINE-3-CARBOXYLIC ETHYL ESTER 4-HYDROXY-6,7-DICHLOROQUINOLINE ETHYL 6-CHLORO-8-FLUORO-4-HYDROXY-3-QUINOLINECARBOXYLATE 6-CHLORO-4-HYDROXY-8-METHYLQUINOLINE-3-CARBOXYLIC ACID 6,8-DICHLORO-4-HYDROXYQUINOINE-3-CARBOXYLIC ACID ETHYL ESTER 6-CHLORO-4-HYDROXY-8-METHYLQUINOLINE ETHYL 6-CHLORO-4-HYDROXYQUINOLINE-3-CARBOXYLATE 3-Quinolinecarboxylic acid, 6-chloro-4-hydroxy-2-phenyl-, ethyl ester ETHYL 8-BENZOYL-6-CHLORO-4-HYDROXY-3-QUINOLINECARBOXYLATE 2,6-DICHLORO-8-METHYL-3-PHENYLQUINOLIN-4-OL BUTTPARK 19\09-86 6-CHLORO-2,8-DIMETHYL-4-QUINOLINOL

4-HYDROXY-6-CHLOROQUINOLINE

6-CHLORO-4-HYDROXYQUINOLINE

6-CHLOROQUINOLIN-4(1H)-ONE

6-CHLOROQUINOLIN-4-OL

6-CHLORO-4-QUINOLINOL

4-Quinolinol, 6-chloro-

23432-43-1