ChemicalBook > CAS DataBase List > 6-CHLORO-4-HYDROXYQUINOLINE

6-CHLORO-4-HYDROXYQUINOLINE

Product Name
6-CHLORO-4-HYDROXYQUINOLINE
CAS No.
23432-43-1
Chemical Name
6-CHLORO-4-HYDROXYQUINOLINE
Synonyms
6-CHLORO-4-QUINOLINOL;6-CHLOROQUINOLIN-4-OL;4-Quinolinol, 6-chloro-;6-CHLOROQUINOLIN-4(1H)-ONE;6-CHLORO-4-HYDROXYQUINOLINE;4-HYDROXY-6-CHLOROQUINOLINE
CBNumber
CB5711644
Molecular Formula
C9H6ClNO
Formula Weight
179.6
MOL File
23432-43-1.mol
More
Less

6-CHLORO-4-HYDROXYQUINOLINE Property

Melting point:
269°C(lit.)
Boiling point:
348.5±22.0 °C(Predicted)
Density 
1.412±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
form 
powder to crystal
pka
3.89±0.40(Predicted)
color 
White to Light gray to Light yellow
InChIKey
XXGUQCVVGPZTPF-UHFFFAOYSA-N
More
Less

Safety

Hazard Codes 
E,Xn
Risk Statements 
22
HS Code 
2933499090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
OTV000284
Product name
6-Chloro-4-quinolinol
Purity
AldrichCPR
Packaging
1G
Price
$216
Updated
2025/07/31
TCI Chemical
Product number
C3312
Product name
6-Chloro-4-quinolinol
Purity
>98.0%(GC)
Packaging
1g
Price
$37
Updated
2025/07/31
TCI Chemical
Product number
C3312
Product name
6-Chloro-4-quinolinol
Purity
>98.0%(GC)
Packaging
5g
Price
$113
Updated
2025/07/31
TRC
Product number
B419428
Product name
6-Chloroquinolin-4-ol
Packaging
100mg
Price
$60
Updated
2021/12/16
Chem-Impex
Product number
44898
Product name
6-Chloro-4-quinolinol,≥98%(GC)
Purity
≥98%(GC)
Packaging
1G
Price
$51.39
Updated
2021/12/16
More
Less

6-CHLORO-4-HYDROXYQUINOLINE Chemical Properties,Usage,Production

Chemical Properties

off White powder

Synthesis

21617-20-9

23432-43-1

General procedure for the synthesis of 4-hydroxy-6-chloroquinoline from 6-chloro-4-oxo-2,3-dihydroquinoline: 6-chloro-4-oxo-2,3-dihydroquinoline (0.01 mol) was placed in a 25 mL reaction flask, and 15 mL of acetonitrile and acetic acid (0.01 mol) were added and stirred for 20 min. Subsequently, hydrogen peroxide (0.03 mol) was added slowly and the reaction was stirred at 65 °C. The progress of the reaction was monitored by thin layer chromatography (TLC) and the reaction was terminated after 7 hours. After the reaction solution was cooled to room temperature, it was poured into 50 mL of water, stirred and filtered to obtain the crude product of 4-hydroxy-6-chloroquinoline. The crude product was purified by silica gel column chromatography (silica gel 100-200 mesh, eluent was petroleum ether:ethyl acetate=1:4), and the target component was collected and concentrated to obtain the pure product. The product yield was 88% and purity was 96%.

References

[1] Patent: CN108794396, 2018, A. Location in patent: Paragraph 0017
[2] Journal of the American Chemical Society, 1949, vol. 71, p. 1906,1910

6-CHLORO-4-HYDROXYQUINOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

6-CHLORO-4-HYDROXYQUINOLINE Suppliers

Americas 1 Canada 1 China 98 Europe 3 Germany 2 India 2 Japan 2 United Kingdom 4 United States 16 Global 129
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2802
Advantage
65
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9309
Advantage
66
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9883
Advantage
59
Chengdu Forest Science and Technology Development Co., Ltd.
Tel
18030648795
Fax
028-61777050
Email
sales@cdforestchem.com
Country
China
ProdList
2000
Advantage
58
SuZhou ShiYa Biopharmaceuticals, Inc.
Tel
86(512)5235 8471 17715136450
Fax
86(512)5235 6881
Email
sales@shiyabiopharm.com
Country
China
ProdList
4169
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Suzhou Ryan Pharmachem Technology Co.,Ltd
Tel
0512-66585217 13962137180
Fax
0512-82177549
Email
sales@ryanchem.com
Country
China
ProdList
384
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9476
Advantage
58
ShangHai AmK Pharmaceutical Technology Co., Ltd.
Tel
微信 17321281695 18019252918
Fax
17321281695
Email
sale@amkchem.com
Country
China
ProdList
15136
Advantage
55
AN PharmaTech Co Ltd
Tel
86(21)68097365
Fax
86(21)33321566
Email
sales@anpharma.net
Country
China
ProdList
4891
Advantage
55
Xi'an NewProChem Co.,Ltd.
Tel
15332490153
Fax
QQ 2725398181
Email
newprochem@126.com
Country
China
ProdList
991
Advantage
55
Struchem Co., Ltd.
Tel
0512-63009836 18994340901
Fax
0512-63006936
Email
helen@struchem.com
Country
China
ProdList
3981
Advantage
60
NovoChemy Ltd.
Tel
86-(0)21-31261262 373522135
Fax
86-(0)21-33250524
Email
sales@novochemy.com
Country
China
ProdList
6498
Advantage
58
Wuhan Chemwish Technology Co.， Ltd
Tel
027-67849912
Fax
027-87531808
Email
sales@chemwish.com
Country
China
ProdList
9148
Advantage
60
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
3495
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20794
Advantage
60
Chengdu Huachun Technology Co., Ltd
Tel
400-1166-196 15982826727
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shanghai Aoyeah Chemical Technology Co., Ltd.
Tel
021-021-64367138 15900495324
Fax
QQ：2504753890
Email
sales@aoyeahchem.com
Country
China
ProdList
197
Advantage
55
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20）
Fax
0539-6362799（To 20）
Country
China
ProdList
10007
Advantage
58
Shanghai Zhen Li Biological Technology Co., Ltd
Tel
021-16621358918; 18516310516
Fax
13045646768
Email
zhenlipharma888@163.com
Country
China
ProdList
19035
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718; +8613336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29735
Advantage
60
Aikon International Limited
Tel
025-58859352 18068836627
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
16027
Advantage
58
Wuhan FengyaoTonghui Chemical Products Co., Ltd.
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17987
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
Changzhou Anchor Biological Technology Co., Ltd
Tel
0519-85519868 18915088878
Fax
0519-85512868
Email
sales@ankerbio.com
Country
China
ProdList
261
Advantage
58
Nanjing holy chemical co., LTD
Tel
19951936396
Email
1815156226@qq.com
Country
China
ProdList
2947
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Shanghai Medicil Biomedical Co., Ltd.
Tel
021-50822001
Email
marketing@medicilon.com.cn
Country
China
ProdList
1152
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2815688 13927872512
Fax
0751-8963795
Email
3007421951@qq.com
Country
China
ProdList
9939
Advantage
58
Chengdu Forest Science and Technology Development Co,. Ltd
Tel
028-87925786 18010564218
Fax
028-61777050
Email
vendi@cdforestchem.com
Country
China
ProdList
1992
Advantage
58
Henan Alpha Chemical Co., Ltd.
Tel
0371-55055611 18137792234
Fax
QQ：3002694073
Email
3002694073@qq.com
Country
China
ProdList
9987
Advantage
58
Xinyi Kaiwu Chemical Technology Co., Ltd.
Tel
0516-0516-88997009 18651776937
Email
4164357@qq.com
Country
China
ProdList
3204
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418671 +8618949823763
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34563
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
SIMAGCHEM CORP
Tel
+86-5922680277 +86-13806087780
Email
sale@simagchem.com
Country
China
ProdList
17346
Advantage
58
Wuhan Chemwish Technology Co., Ltd
Tel
027-67849912
Email
sales@chemwish.com
Country
CHINA
ProdList
10821
Advantage
58
Qi Qi hang Biotechnology Co., Ltd.
Tel
18151111370
Email
1046215251@qq.com
Country
China
ProdList
5999
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29798
Advantage
58
Hebei Fanbo Pharmaceutical Technology Co., Ltd.
Tel
0531-0531-88163906-805-805 15588346797
Email
fanbomedical@163.com
Country
China
ProdList
564
Advantage
58
Changzhou Kechem Bio-Scientific Co., LTD.
Tel
0519-68985668 13685222090
Fax
qq735434464
Email
sales@kechem.cn
Country
China
ProdList
26028
Advantage
58
More
Less

View Lastest Price from 6-CHLORO-4-HYDROXYQUINOLINE manufacturers

Career Henan Chemical Co
Product
6-CHLORO-4-HYDROXYQUINOLINE 23432-43-1
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
10000KGS
Release date
2020-01-11

23432-43-1, 6-CHLORO-4-HYDROXYQUINOLINERelated Search:

6-CHLORO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID 6-CHLORO-4-HYDROXY-2-METHYLQUINOLINE 6-CHLORO-4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINE 6,8-DICHLORO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL 4-HYDROXY-6,8-DICHLOROQUINOLINE 6-CHLORO-4-HYDROXYQUINOLINE 6-CHLORO-4-HYDROXY-8-METHYLQUINOLINE-3-CARBOXYLIC ETHYL ESTER 4-HYDROXY-6,7-DICHLOROQUINOLINE ETHYL 6-CHLORO-8-FLUORO-4-HYDROXY-3-QUINOLINECARBOXYLATE 6-CHLORO-4-HYDROXY-8-METHYLQUINOLINE-3-CARBOXYLIC ACID 6,8-DICHLORO-4-HYDROXYQUINOINE-3-CARBOXYLIC ACID ETHYL ESTER 6-CHLORO-4-HYDROXY-8-METHYLQUINOLINE ETHYL 6-CHLORO-4-HYDROXYQUINOLINE-3-CARBOXYLATE 3-Quinolinecarboxylic acid, 6-chloro-4-hydroxy-2-phenyl-, ethyl ester ETHYL 8-BENZOYL-6-CHLORO-4-HYDROXY-3-QUINOLINECARBOXYLATE 2,6-DICHLORO-8-METHYL-3-PHENYLQUINOLIN-4-OL BUTTPARK 19\09-86 6-CHLORO-2,8-DIMETHYL-4-QUINOLINOL

  • 4-HYDROXY-6-CHLOROQUINOLINE
  • 6-CHLORO-4-HYDROXYQUINOLINE
  • 6-CHLOROQUINOLIN-4(1H)-ONE
  • 6-CHLOROQUINOLIN-4-OL
  • 6-CHLORO-4-QUINOLINOL
  • 4-Quinolinol, 6-chloro-
  • 23432-43-1